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  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
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We are analyzing https://www.nature.com/articles/s41423-018-0005-3.

Title:
Chemokine and chemotactic signals in dendritic cell migration | Cellular & Molecular Immunology
Description:
Dendritic cells (DCs) are professional antigen-presenting cells responsible for the activation of specific T-cell responses and for the development of immune tolerance. Immature DCs reside in peripheral tissues and specialize in antigen capture, whereas mature DCs reside mostly in the secondary lymphoid organs where they act as antigen-presenting cells. The correct localization of DCs is strictly regulated by a large variety of chemotactic and nonchemotactic signals that include bacterial products, DAMPs (danger-associated molecular patterns), complement proteins, lipids, and chemokines. These signals function both individually and in concert, generating a complex regulatory network. This network is regulated at multiple levels through different strategies, such as synergistic interactions, proteolytic processing, and the actions of atypical chemokine receptors. Understanding this complex scenario will help to clarify the role of DCs in different pathological conditions, such as autoimmune diseases and cancers and will uncover new molecular targets for therapeutic interventions.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Science
  • Telecommunications

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

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🌠 Phenomenal Traffic: 5M - 10M visitors per month


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Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$63,100 per month
Estimations show Nature.com's display ad online revenue falls between $42,042 and $115,616 per month.

Keywords {🔍}

pubmed, google, scholar, cas, dendritic, cells, cell, immunol, central, chemokine, migration, plasmacytoid, receptors, receptor, human, nature, ccr, sozzani, immunity, chemokines, blood, lymph, del, prete, med, recruitment, article, atypical, skin, biol, exp, responses, role, trafficking, ccl, expression, development, access, rev, function, dcs, nodes, content, molecular, activation, immune, nat, inflammatory, promotes, inflamed,

Topics {✒️}

nature portfolio permissions reprints research institute privacy policy advertising nature 392 nature 498 nature 449 nature social media monocyte-derived dendritic cells intracellular cell-related genes xcr1-expressing dendritic cells ccr9 + plasmacytoid dendritic cells cxcr2-dependent neutrophil recruitment xcr1-xcl1 chemokine axis ifn-producing cells respond chemokine-guided cell positioning cxcr5-expressing dendritic cells drive anti-tumor responses enable ccr7-dependent trafficking t-helper type-1 response specific t-cell responses francesca sozio & silvano sozzani human psoriatic lesions generating t-cell responses personal data superior antigen cross-presentation human monocyte-derived cxcr4-mediated signaling promote central tolerance mouse cd8 + dendritic cells antigen-presenting cell function author correspondence dendritic cell development springerlink instant access skin requires docking data protection naturally occurring cc-chemokines permissions dendritic cell biology monocyte-derived immature thymic dendritic cells bone marrow plasmacytoid dendritic cells chemokine receptor xcr1 annalisa del prete human dendritic cells cytokine growth factor haptotactic chemokine gradients

Schema {🗺️}

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         headline:Chemokine and chemotactic signals in dendritic cell migration
         description:Dendritic cells (DCs) are professional antigen-presenting cells responsible for the activation of specific T-cell responses and for the development of immune tolerance. Immature DCs reside in peripheral tissues and specialize in antigen capture, whereas mature DCs reside mostly in the secondary lymphoid organs where they act as antigen-presenting cells. The correct localization of DCs is strictly regulated by a large variety of chemotactic and nonchemotactic signals that include bacterial products, DAMPs (danger-associated molecular patterns), complement proteins, lipids, and chemokines. These signals function both individually and in concert, generating a complex regulatory network. This network is regulated at multiple levels through different strategies, such as synergistic interactions, proteolytic processing, and the actions of atypical chemokine receptors. Understanding this complex scenario will help to clarify the role of DCs in different pathological conditions, such as autoimmune diseases and cancers and will uncover new molecular targets for therapeutic interventions.
         datePublished:2018-03-21T00:00:00Z
         dateModified:2018-03-21T00:00:00Z
         pageStart:346
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      headline:Chemokine and chemotactic signals in dendritic cell migration
      description:Dendritic cells (DCs) are professional antigen-presenting cells responsible for the activation of specific T-cell responses and for the development of immune tolerance. Immature DCs reside in peripheral tissues and specialize in antigen capture, whereas mature DCs reside mostly in the secondary lymphoid organs where they act as antigen-presenting cells. The correct localization of DCs is strictly regulated by a large variety of chemotactic and nonchemotactic signals that include bacterial products, DAMPs (danger-associated molecular patterns), complement proteins, lipids, and chemokines. These signals function both individually and in concert, generating a complex regulatory network. This network is regulated at multiple levels through different strategies, such as synergistic interactions, proteolytic processing, and the actions of atypical chemokine receptors. Understanding this complex scenario will help to clarify the role of DCs in different pathological conditions, such as autoimmune diseases and cancers and will uncover new molecular targets for therapeutic interventions.
      datePublished:2018-03-21T00:00:00Z
      dateModified:2018-03-21T00:00:00Z
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         Biomedicine
         general
         Immunology
         Medical Microbiology
         Microbiology
         Antibodies
         Vaccine
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      name:Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy
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      name:Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy
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