
NATURE . COM {
}
Title:
Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death | Cell Death & Disease
Description:
Drug combinations have been increasingly applied in chemotherapy as a strategy to enhance the efficacy of anti-cancer treatment. The appropriate drug combinations may achieve synergistic effects beyond monotherapies alone. AC220 (Quizartinib), an FLT3 receptor tyrosine kinase inhibitor, developed for the treatment of AML, has been tested in phase II human clinical trials. However, AC220 as a monotherapy is not efficacious enough. In this study, we performed a small-molecule screening of 12 640 compounds in order to find a compound that increase the AC220 efficacy in chemotherapy. We identified that TAK-165, a HER2 inhibitor, even when used at low nanomolar doses in combination with AC220, was able to induce cell death in different cancer cells, but not in non-cancer cell lines. We showed that TAK-165 and AC220 act synergistically to downregulate key signaling pathways and potently induce cancer cell death. Furthermore, we demonstrated that TAK-165 inhibited autophagy in a HER2-independent manner. Finally, we showed that the combination of TAK-165 and AC220 induced cell death in cancer cells through the activation of chaperone-mediated autophagy. Overall, these findings support the strategy for using AC220 and an autophagy inhibitor such as TAK-165 in a combinatorial treatment to enhance the efficacy of cancer therapies.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {๐}
- Science
- Health & Fitness
- Telecommunications
Content Management System {๐}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of nature.com audience?
๐ Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {๐ธ}
Display Ads {๐ฏ}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {๐ฐ}
Display Ads {๐ฏ}
$63,100 per month
Our analysis indicates Nature.com generates between $42,042 and $115,616 monthly online from display ads.
Keywords {๐}
cell, cells, cancer, pubmed, tak, autophagy, article, google, scholar, combination, treatment, cas, fig, death, inhibitor, takac, viability, central, activation, treated, lines, flt, assay, cma, breast, sum, aml, chaperonemediated, leukemia, nature, inhibitors, signaling, conditions, effect, kinase, shown, data, performed, induce, inhibition, degradation, therapy, inhibit, combined, negative, levels, pathways, proliferation, resistance, concentrations,
Topics {โ๏ธ}
nature portfolio privacy policy clinical research nature advertising bioactive libraries tnf-a-induced neutrophil apoptosis thermo fisher scientific r-7-cl-o-nec-1โ10โฮผm transforming growth factor-beta reprints celltiter-gloยฎ luminescent assay japan epidermal-growth-factor receptors cell culture media override stromal-mediated chemoresistance hyperstar polymer-based nanoparticles cancer development triple-negative breast cancer acute myeloid leukemia small-cell lung cancer mitogen-activated protein kinase androgen-independent prostate cancer cancer-related flt3 mutations chemical library screening luminescence-based viability assay permissions small-cell lung cancers mda-7 enhances apoptosis-induction mimics glucose-free conditions high proliferative activity culture media activating phosphoinositol-3-kinase author correspondence original author ludwig cancerย center breast triple negative human clinical trials social media induce ligand-independent activation glucose-free conditions shows iii phosphoinositide 3-kinase strong combination index published maps chaperone-mediated autophagy activation promotes cell death mutant flt3-positive aml article ouchida junying yuan tak-165/ac220 combination induces
Questions {โ}
- PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?
Schema {๐บ๏ธ}
WebPage:
mainEntity:
headline:Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death
description:Drug combinations have been increasingly applied in chemotherapy as a strategy to enhance the efficacy of anti-cancer treatment. The appropriate drug combinations may achieve synergistic effects beyond monotherapies alone. AC220 (Quizartinib), an FLT3 receptor tyrosine kinase inhibitor, developed for the treatment of AML, has been tested in phase II human clinical trials. However, AC220 as a monotherapy is not efficacious enough. In this study, we performed a small-molecule screening of 12 640 compounds in order to find a compound that increase the AC220 efficacy in chemotherapy. We identified that TAK-165, a HER2 inhibitor, even when used at low nanomolar doses in combination with AC220, was able to induce cell death in different cancer cells, but not in non-cancer cell lines. We showed that TAK-165 and AC220 act synergistically to downregulate key signaling pathways and potently induce cancer cell death. Furthermore, we demonstrated that TAK-165 inhibited autophagy in a HER2-independent manner. Finally, we showed that the combination of TAK-165 and AC220 induced cell death in cancer cells through the activation of chaperone-mediated autophagy. Overall, these findings support the strategy for using AC220 and an autophagy inhibitor such as TAK-165 in a combinatorial treatment to enhance the efficacy of cancer therapies.
datePublished:2018-01-26T00:00:00Z
dateModified:2018-01-26T00:00:00Z
pageStart:1
pageEnd:14
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/s41419-017-0170-9
keywords:
Life Sciences
general
Biochemistry
Cell Biology
Immunology
Cell Culture
Antibodies
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig6_HTML.jpg
isPartOf:
name:Cell Death & Disease
issn:
2041-4889
volumeNumber:9
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Amanda Tomie Ouchida
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Yingbo Li
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Jiefei Geng
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Ayaz Najafov
url:http://orcid.org/0000-0002-1350-2056
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Dimitry Ofengeim
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Xiaoxiao Sun
affiliation:
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
type:Organization
type:Person
name:Qiang Yu
affiliation:
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
type:Organization
type:Person
name:Junying Yuan
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death
description:Drug combinations have been increasingly applied in chemotherapy as a strategy to enhance the efficacy of anti-cancer treatment. The appropriate drug combinations may achieve synergistic effects beyond monotherapies alone. AC220 (Quizartinib), an FLT3 receptor tyrosine kinase inhibitor, developed for the treatment of AML, has been tested in phase II human clinical trials. However, AC220 as a monotherapy is not efficacious enough. In this study, we performed a small-molecule screening of 12 640 compounds in order to find a compound that increase the AC220 efficacy in chemotherapy. We identified that TAK-165, a HER2 inhibitor, even when used at low nanomolar doses in combination with AC220, was able to induce cell death in different cancer cells, but not in non-cancer cell lines. We showed that TAK-165 and AC220 act synergistically to downregulate key signaling pathways and potently induce cancer cell death. Furthermore, we demonstrated that TAK-165 inhibited autophagy in a HER2-independent manner. Finally, we showed that the combination of TAK-165 and AC220 induced cell death in cancer cells through the activation of chaperone-mediated autophagy. Overall, these findings support the strategy for using AC220 and an autophagy inhibitor such as TAK-165 in a combinatorial treatment to enhance the efficacy of cancer therapies.
datePublished:2018-01-26T00:00:00Z
dateModified:2018-01-26T00:00:00Z
pageStart:1
pageEnd:14
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/s41419-017-0170-9
keywords:
Life Sciences
general
Biochemistry
Cell Biology
Immunology
Cell Culture
Antibodies
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_Fig6_HTML.jpg
isPartOf:
name:Cell Death & Disease
issn:
2041-4889
volumeNumber:9
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Amanda Tomie Ouchida
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Yingbo Li
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Jiefei Geng
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Ayaz Najafov
url:http://orcid.org/0000-0002-1350-2056
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Dimitry Ofengeim
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
type:Person
name:Xiaoxiao Sun
affiliation:
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
type:Organization
type:Person
name:Qiang Yu
affiliation:
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
type:Organization
type:Person
name:Junying Yuan
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Cell Death & Disease
issn:
2041-4889
volumeNumber:9
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Amanda Tomie Ouchida
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Yingbo Li
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Jiefei Geng
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Ayaz Najafov
url:http://orcid.org/0000-0002-1350-2056
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Dimitry Ofengeim
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Xiaoxiao Sun
affiliation:
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
type:Organization
name:Qiang Yu
affiliation:
name:Chinese Academy of Sciences
address:
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
type:PostalAddress
type:Organization
name:Junying Yuan
affiliation:
name:Harvard Medical School
address:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
name:Harvard Medical School
address:
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Department of Cell Biology, Harvard Medical School, Boston, USA
name:Department of Cell Biology, Harvard Medical School, Boston, USA
name:Department of Cell Biology, Harvard Medical School, Boston, USA
name:Department of Cell Biology, Harvard Medical School, Boston, USA
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
name:Department of Cell Biology, Harvard Medical School, Boston, USA
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
name:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
name:Department of Cell Biology, Harvard Medical School, Boston, USA
name:Ludwig Cancer Center, Harvard Medical School, Boston, USA
External Links {๐}(247)
- https://orcid.org/0000-0002-1350-2056 income
- What's the financial gain of https://link.springer.com/doi/10.1186/1756-8722-4-13?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21453545 generate?
- Check the income stats for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076284
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Downstream%20molecular%20pathways%20of%20FLT3%20in%20the%20pathogenesis%20of%20acute%20myeloid%20leukemia%3A%20biology%20and%20therapeutic%20implications&journal=J.%20Hematol.%20Oncol.&doi=10.1186%2F1756-8722-4-13&volume=4&publication_year=2011&author=Takahashi%2CS have monthly?
- How much money does https://doi.org/10.1038%2Fnrc1169 generate?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12951584 earn?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20FLT3%20in%20haematopoietic%20malignancies&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc1169&volume=3&pages=650-665&publication_year=2003&author=Stirewalt%2CDL&author=Radich%2CJP?
- How much income does https://doi.org/10.21037%2Fsci.2017.05.04 have?
- How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=28607922 have?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460107 earn?
- How much does http://scholar.google.com/scholar_lookup?&title=Tyrosine%20kinase%20inhibitors%20targeting%20FLT3%20in%20the%20treatment%20of%20acute%20myeloid%20leukemia&journal=Stem%20Cell%20Investig.&doi=10.21037%2Fsci.2017.05.04&volume=4&pages=48-48&publication_year=2017&author=Chen%2CY pull in monthly?
- What's the monthly money flow for https://doi.org/10.1038%2Fsj.leu.2403099?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12970773
- http://scholar.google.com/scholar_lookup?&title=FLT3%3A%20ITDoes%20matter%20in%20leukemia&journal=Leukemia&doi=10.1038%2Fsj.leu.2403099&volume=17&pages=1738-1752&publication_year=2003&author=Levis%2CM&author=Small%2CD's total income per month
- What's https://link.springer.com/doi/10.1186/1476-4598-12-19's gross income?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23497317 produce monthly?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637582?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Quizartinib%20%28AC220%29%20is%20a%20potent%20second%20generation%20class%20III%20tyrosine%20kinase%20inhibitor%20that%20displays%20a%20distinct%20inhibition%20profile%20against%20mutant-FLT3%2C%20-PDGFRA%20and%20-KIT%20isoforms&journal=Mol.%20Cancer&doi=10.1186%2F1476-4598-12-19&volume=12&publication_year=2013&author=Kampa-Schittenhelm%2CKM produce monthly?
- What's the financial outcome of https://doi.org/10.1182%2Fblood-2009-05-222034?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19654408
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756206 net monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=AC220%20is%20a%20uniquely%20potent%20and%20selective%20inhibitor%20of%20FLT3%20for%20the%20treatment%20of%20acute%20myeloid%20leukemia%20%28AML%29&journal=Blood&doi=10.1182%2Fblood-2009-05-222034&volume=114&pages=2984-2992&publication_year=2009&author=Zarrinkar%2CPP generate monthly?
- How much revenue does https://doi.org/10.1517%2F13543784.2013.842973 produce monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24070241 rake in every month?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20quizartinib%20in%20the%20treatment%20of%20acute%20myeloid%20leukemia&journal=Expert.%20Opin.%20Investig.%20Drugs&doi=10.1517%2F13543784.2013.842973&volume=22&pages=1659-1669&publication_year=2013&author=Ostronoff%2CF&author=Estey%2CE?
- http://scholar.google.com/scholar_lookup?&title=Phase%20IB%20study%20of%20the%20FLT3%20kinase%20inhibitor%20midostaurin%20with%20chemotherapy%20in%20younger%20newly%20diagnosed%20adult%20patients%20with%20acute%20myeloid%20leukemia&journal=Leukemia&volume=33&pages=1223-1229&publication_year=2009&author=Reedijk%2CM's revenue stream
- What's the profit of https://doi.org/10.1158%2F1078-0432.CCR-15-1998?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26920889 make?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=A%20Phase%20I%20study%20of%20quizartinib%20combined%20with%20chemotherapy%20in%20relapsed%20childhood%20leukemia%3A%20a%20therapeutic%20advances%20in%20childhood%20leukemia%20%26%20lymphoma%20%28TACL%29%20Study&journal=Clin.%20Cancer%20Res.&doi=10.1158%2F1078-0432.CCR-15-1998&volume=22&pages=4014-4022&publication_year=2016&author=Cooper%2CTM
- How much cash flow does https://doi.org/10.1038%2Fnrc1692 have monthly?
- What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16148885?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20autophagy%20in%20cancer%20development%20and%20response%20to%20therapy&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc1692&volume=5&pages=726-734&publication_year=2005&author=Kondo%2CY&author=Kanzawa%2CT&author=Sawaya%2CR&author=Kondo%2CS bring in each month?
- Profit of https://doi.org/10.1146%2Fannurev-biophys-060414-034248
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25747593
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Mechanisms%20of%20autophagy&journal=Annu%20Rev.%20Biophys.&doi=10.1146%2Fannurev-biophys-060414-034248&volume=44&pages=101-122&publication_year=2015&author=Noda%2CNN&author=Inagaki%2CF?
- Monthly income for https://doi.org/10.1016%2F0014-5793%2893%2980398-E
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8224160 earn?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Isolation%20and%20characterization%20of%20autophagy-defective%20mutants%20of%20Saccharomyces%20cerevisiae&journal=FEBS%20Lett.&doi=10.1016%2F0014-5793%2893%2980398-E&volume=333&pages=169-174&publication_year=1993&author=Tsukada%2CM&author=Ohsumi%2CY?
- Learn how profitable https://doi.org/10.5732%2Fcjc.011.10185 is on a monthly basis
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21959043 earn?
- How much revenue does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012266 produce monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Modulating%20autophagy%3A%20a%20strategy%20for%20cancer%20therapy&journal=Chin.%20J.%20Cancer&doi=10.5732%2Fcjc.011.10185&volume=30&pages=655-668&publication_year=2011&author=Li%2CJL&author=Han%2CSL&author=Fan%2CX earn?
- What's the income of https://doi.org/10.1124%2Fmol.114.091850?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24574520
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014668 income
- How much does http://scholar.google.com/scholar_lookup?&title=Autophagy%20and%20cancer%20therapy&journal=Mol.%20Pharmacol.&doi=10.1124%2Fmol.114.091850&volume=85&pages=830-838&publication_year=2014&author=Thorburn%2CA&author=Thamm%2CDH&author=Gustafson%2CDL make?
- How much profit does https://doi.org/10.1038%2Fcddis.2013.350 make?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24113172?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824660?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Autophagy%20and%20chemotherapy%20resistance%3A%20a%20promising%20therapeutic%20target%20for%20cancer%20treatment&journal=Cell%20Death%20Dis.&doi=10.1038%2Fcddis.2013.350&volume=4&publication_year=2013&author=Sui%2CX generate?
- How much does https://doi.org/10.1083%2Fjcb.201503044 net monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26323688 rake in every month?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555813?
- How much income does http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20HK2%20by%20chaperone-mediated%20autophagy%20promotes%20metabolic%20catastrophe%20and%20cell%20death&journal=J.%20Cell.%20Biol.&doi=10.1083%2Fjcb.201503044&volume=210&pages=705-716&publication_year=2015&author=Xia%2CHg have?
- What's the income of https://doi.org/10.1111%2Fj.1442-2042.2006.01342.x?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16771730 is on a monthly basis
- How much money does http://scholar.google.com/scholar_lookup?&title=Novel%20HER2%20selective%20tyrosine%20kinase%20inhibitor%2C%20TAK-165%2C%20inhibits%20bladder%2C%20kidney%20and%20androgen-independent%20prostate%20cancer%20in%20vitro%20and%20in%20vivo&journal=Int.%20J.%20Urol.&doi=10.1111%2Fj.1442-2042.2006.01342.x&volume=13&pages=587-592&publication_year=2006&author=Nagasawa%2CJ make?
- What's the monthly income of https://doi.org/10.1038%2Fnrclinonc.2016.66?
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27184417
- Income figures for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461122
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Triple-negative%20breast%20cancer%3A%20challenges%20and%20opportunities%20of%20a%20heterogeneous%20disease&journal=Nat.%20Rev.%20Clin.%20Oncol.&doi=10.1038%2Fnrclinonc.2016.66&volume=13&pages=674-690&publication_year=2016&author=Bianchini%2CG&author=Balko%2CJM&author=Mayer%2CIA&author=Sanders%2CME&author=Gianni%2CL?
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11504778 making per month?
- How much does http://scholar.google.com/scholar_lookup?&title=Drug%20synergism%3A%20its%20detection%20and%20applications&journal=J.%20Pharmacol.%20Exp.%20Ther.&volume=298&pages=865-872&publication_year=2001&author=Tallarida%2CRJ pull in monthly?
- What are the earnings of https://doi.org/10.1038%2Fnbt.1549?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Synergistic%20drug%20combinations%20improve%20therapeutic%20selectivity&journal=Nat.%20Biotechnol.&doi=10.1038%2Fnbt.1549&volume=27&pages=659-666&publication_year=2010&author=Leh%C3%A0r%2CJ?
- Earnings of https://doi.org/10.1177%2F1947601912440575
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22737266?
- What's the profit of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379564?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Quantitative%20methods%20for%20assessing%20drug%20synergism&journal=Genes%20Cancer&doi=10.1177%2F1947601912440575&volume=2&pages=1003-1008&publication_year=2011&author=Tallarida%2CRJ
- How much does https://doi.org/10.1038%2Fsj.onc.1210477 pull in monthly?
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17471238 each month?
- What's the income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021475?
- See how much http://scholar.google.com/scholar_lookup?&title=The%20oncogene%20HER2%3B%20its%20signaling%20ans%20transforming%20functions%20ant%20its%20role%20in%20human%20cancer%20pathogenesis&journal=Oncogene&doi=10.1038%2Fsj.onc.1210477&volume=26&pages=6469-6487&publication_year=2007&author=Moasser%2CMM makes per month
- How much income does https://link.springer.com/doi/10.1186/bcr1652 have?
- Revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868927
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=HER2%20therapy.%20Small%20molecule%20HER-2%20tyrosine%20kinase%20inhibitors&journal=Breast%20Cancer%20Res.&doi=10.1186%2Fbcr1652&volume=9&publication_year=2007&author=Spector%2CN&author=Xia%2CW&author=El-Hariry%2CI&author=Yarden%2CY&author=Bacus%2CS?
- How much does https://doi.org/10.1038%2Fsj.cr.7290105 pull in?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11942415 make?
- How much profit does http://scholar.google.com/scholar_lookup?&title=MAPK%20signal%20pathways%20in%20the%20regulation%20of%20cell%20proliferation%20in%20mammalian%20cells&journal=Cell.%20Res.&doi=10.1038%2Fsj.cr.7290105&volume=12&pages=9-18&publication_year=2002&author=Zhang%2CW&author=Liu%2CHT&author=Tu%2CLIUH generate?
- What are the earnings of https://link.springer.com/doi/10.1186/2162-3619-2-29?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24502434 make?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176492 gross monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Tumor%20dormancy%3A%20potential%20therapeutic%20target%20in%20tumor%20recurrence%20and%20metastasis%20prevention&journal=Exp.%20Hematol.%20Oncol.&doi=10.1186%2F2162-3619-2-29&volume=2&publication_year=2013&author=Wang%2CSH&author=Lin%2CSY generate monthly?
- How much profit does https://doi.org/10.1038%2Fcr.2013.153 make?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24281265 pull in monthly?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Chaperone-mediated%20autophagy%3A%20roles%20in%20disease%20and%20aging&journal=Cell.%20Res.&doi=10.1038%2Fcr.2013.153&volume=24&pages=92-104&publication_year=2014&author=Cuervo%2CAM&author=Wong%2CE produce monthly?
- How profitable is https://doi.org/10.1002%2Fjcp.24569?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24477641
- How much cash flow does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310550 have monthly?
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Phosphorylation-regulated%20degradation%20of%20the%20tumor-suppressor%20form%20of%20PED%20by%20chaperone-mediated%20autophagy%20in%20lung%20cancer%20cells&journal=J.%20Cell.%20Physiol.&doi=10.1002%2Fjcp.24569&volume=229&pages=1359-1368&publication_year=2014&author=Quintavalle%2CC?
- How much money does https://doi.org/10.1091%2Fmbc.9.8.1995 make?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9693362's financial summary
- How much profit is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC25451 making per month?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=IkappaB%20is%20a%20substrate%20for%20a%20selective%20pathway%20of%20lysosomal%20proteolysis&journal=Mol.%20Biol.%20Cell.&doi=10.1091%2Fmbc.9.8.1995&volume=9&pages=1995-2010&publication_year=1998&author=Cuervo%2CAM&author=Hu%2CW&author=Lim%2CB&author=Dice%2CJF
- What's the total monthly financial gain of https://doi.org/10.1146%2Fannurev.med.53.082901.103929?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11818492?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Mechanisms%20of%20cancer%20drug%20resistance&journal=Annu.%20Rev.%20Med.&doi=10.1146%2Fannurev.med.53.082901.103929&volume=53&pages=615-627&publication_year=2002&author=Gottesman%2CMM making per month?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Drug%20resistance%20in%20cancer%3A%20An%20overview&pages=1769-1792&publication_year=2014&author=Housman%2CG?
- Monthly income for https://doi.org/10.1002%2Fjcp.20472
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Combinatorial%20treatment%20of%20non-small-cell%20lung%20cancers%20with%20gefitinib%20and%20ad.mda-7%20enhances%20apoptosis-induction%20and%20reverses%20resistance%20to%20a%20single%20therapy&journal=J.%20Cell.%20Physiol.&doi=10.1002%2Fjcp.20472&volume=207&pages=12-22&publication_year=2006&author=Eriksson%2CM&author=Taskinen%2CM&author=Lepp%C3%A4%2CS generate?
- How much money does https://doi.org/10.1016%2Fj.molonc.2012.02.004 generate?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22440008
- How much income is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476506 earning monthly?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Discovery%20of%20small%20molecule%20cancer%20drugs%3A%20Successes%2C%20challenges%20and%20opportunities&journal=Mol.%20Oncol.&doi=10.1016%2Fj.molonc.2012.02.004&volume=6&pages=155-176&publication_year=2012&author=Hoelder%2CS&author=Clarke%2CPA&author=Workman%2CP
- What's the income generated by https://doi.org/10.1039%2FC5CC07709E each month?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26434941
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Combinatorial%20therapy%20for%20triple%20negative%20breast%20cancer%20using%20hyperstar%20polymer-based%20nanoparticles&journal=Chem.%20Commun.%20%28Camb.%29.&doi=10.1039%2FC5CC07709E&volume=51&pages=16710-16713&publication_year=2015&author=Misra%2CSK
- How much money does http://scholar.google.com/scholar_lookup?&title=HER%202%3A%20biology%2C%20detection%2C%20and%20clinical%20implications&journal=Arch.%20Pathol.&volume=135&pages=55-62&publication_year=2011&author=Gutierrez%2CC&author=Schiff%2CR make?
- How much profit does https://doi.org/10.1038%2Fnrc1609 make?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15864276?
- How much does http://scholar.google.com/scholar_lookup?&title=ERBB%20receptors%20and%20cancer%3A%20the%20complexity%20of%20targeted%20inhibitors&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc1609&volume=5&pages=341-354&publication_year=2005&author=Hynes%2CNE&author=Lane%2CHa make?
- How much profit is https://doi.org/10.1038%2Fsrep24589 making per month?
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27074819 each month?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830980 rake in every month?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=The%20HER2%20inhibitor%20TAK165%20sensitizes%20human%20acute%20myeloid%20leukemia%20cells%20to%20retinoic%20acid-induced%20myeloid%20differentiation%20by%20activating%20MEK%2FERK%20mediated%20RAR%CE%B1%2FSTAT1%20axis&journal=Sci.%20Rep.&doi=10.1038%2Fsrep24589&volume=6&publication_year=2016&author=Shao%2CX
- How much cash flow does https://doi.org/10.1016%2FS1470-2045%2803%2901137-9 have monthly?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12850190?
- How much does http://scholar.google.com/scholar_lookup?&title=Inhibitors%20of%20epidermal-growth-factor%20receptors%3A%20a%20review%20of%20clinical%20research%20with%20a%20focus%20on%20non-small-cell%20lung%20cancer&journal=Lancet%20Oncol.&doi=10.1016%2FS1470-2045%2803%2901137-9&volume=4&pages=397-406&publication_year=2003&author=Sridhar%2CSS&author=Seymour%2CL&author=Shepherd%2CFA pull in?
- How much does https://doi.org/10.1002%2Fijc.2910610621 net monthly?
- See how much http://scholar.google.com/scholar_lookup?&title=Circumvention%20od%20confluence-dependent%20resistance%20in%20a%20human%20multi-drug-resistant%20colon-cancer%20cell%20line&journal=Int.%20J.%20Cancer&doi=10.1002%2Fijc.2910610621&volume=879&pages=873-879&publication_year=1995&author=Garrido%2CC&author=Chauffert%2CB&author=Pinard%2CD&author=Tibaut%2CF&author=Genne%2CP makes per month
- What are the total earnings of https://doi.org/10.1016%2Fj.mrrev.2003.06.004?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14644317?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Effect%20of%20cell%20confluence%20on%20ultraviolet%20light%20apoptotic%20responses%20in%20DNA%20repair%20deficient%20cells&journal=Mutat.%20Res.&doi=10.1016%2Fj.mrrev.2003.06.004&volume=544&pages=159-166&publication_year=2003&author=Carvalho%2CH?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Confluence-dependent%20resistance%20to%20cisplatin%20in%20lung%20cancer%20cells%20is%20regulated%20by%20transforming%20growth%20factor-beta&journal=Exp.%20Lung.%20Res.&volume=2148&pages=1-8&publication_year=2016&author=Yokokura%2CS?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11686294?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=PKB%2FAkt%3A%20a%20key%20mediator%20of%20cell%20proliferation%2C%20survival%20and%20insulin%20responses%3F&journal=J.%20Cell.%20Sci.&volume=114&pages=2903-2910&publication_year=2001&author=Lawlor%2CMA&author=Alessi%2CDR
- How much cash flow does https://doi.org/10.1128%2FMCB.24.1.200-216.2004 have monthly?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14673156?
- How much income is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC303352 earning monthly?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=mTOR%20controls%20cell%20cycle%20progression%20through%20its%20cell%20growth%20effectors%20S6K1%20and%204E-BP1%20%2F%20eukaryotic%20translation%20initiation%20factor%204E%20mTOR%20controls%20cell%20cycle%20progression%20through%20its%20cell%20growth%20effectors%20S6K1%20and%204E-BP1%20%2F%20eukaryotic%20translation%20initiation&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.24.1.200-216.2004&volume=24&pages=200-216&publication_year=2004&author=Fingar%2CDC is on a monthly basis
- How much income is https://doi.org/10.1111%2Fj.1582-4934.2005.tb00337.x earning monthly?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15784165?
- http://scholar.google.com/scholar_lookup?&title=The%20activation%20of%20Akt%20%2F%20PKB%20signaling%20pathway%20and%20cell%20survival&journal=J.%20Cell.%20Mol.%20Med.&doi=10.1111%2Fj.1582-4934.2005.tb00337.x&volume=9&pages=59-71&publication_year=2005&author=Song%2CG&author=Ouyang%2CG&author=Bao%2CS's financial summary
- How much profit is https://doi.org/10.1038%2Fsj.onc.1209100 making per month?
- Income figures for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16288285
- How much does http://scholar.google.com/scholar_lookup?&title=AKT%20signaling%20in%20normal%20and%20malignant%20cells&journal=Oncogene&doi=10.1038%2Fsj.onc.1209100&volume=24&pages=7391-7393&publication_year=2005&author=Testa%2CJR&author=Tsichlis%2CPN rake in every month?
- How much profit does https://doi.org/10.1038%2Fnrc2254 generate?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17972889 rake in every month?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866167?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Role%20of%20autophagy%20in%20cancer&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc2254&volume=7&pages=961-967&publication_year=2007&author=Mathew%2CR&author=Karantza-Wadsworth%2CV&author=White%2CE generate?
- How much revenue does https://doi.org/10.4161%2Fauto.5233 produce monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18000393 earn?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Consideration%20about%20negative%20controls%20for%20LC3%20and%20expression%20vectors%20for%20four%20colored%20fluorescent%20protein-LC3%20negative%20controls&journal=Autophagy&doi=10.4161%2Fauto.5233&volume=4&pages=131-134&publication_year=2008&author=Tanida%2CI produce monthly?
- Check the income stats for https://doi.org/10.1002%2Fpath.2694
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20225337 generate?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989884?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Autophagy%3A%20assays%20and%20artifacts&journal=J.%20Pathol.&doi=10.1002%2Fpath.2694&volume=221&pages=117-124&publication_year=2010&author=Barth%2CS&author=Glick%2CD&author=Macleod%2CKF bring in?
- Explore the financials of https://doi.org/10.4161%2Fauto.2703
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16874105's total income per month
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Autophagy%2C%20bafilomycin%20and%20cell%20death&journal=Autophagy&doi=10.4161%2Fauto.2703&volume=2&pages=228-230&publication_year=2006&author=Shacka%2CJJ&author=Klocke%2CBJ&author=Roth%2CKA?
- How much does https://doi.org/10.1074%2Fjbc.M109.080796 earn?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20123989?
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856291's financial summary
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Dual%20role%20of%203-methyladenine%20in%20modulation%20of%20autophagy%20via%20different%20temporal%20patterns%20of%20inhibition%20on%20class%20I%20and%20III%20phosphoinositide%203-kinase&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M109.080796&volume=285&pages=10850-10861&publication_year=2010&author=Wu%2CYT
- Financial intake of https://link.springer.com/doi/10.1007/s10495-012-0738-x
- Get to know http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22638980's earnings
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Differential%20effects%20of%20the%20autophagy%20inhibitors%203-methyladenine%20and%20chloroquine%20on%20spontaneous%20and%20TNF-a-induced%20neutrophil%20apoptosis&journal=Apoptosis&doi=10.1007%2Fs10495-012-0738-x&volume=17&pages=1050-1065&publication_year=2012&author=Pliyev%2CBK&author=Menshikov%2CM?
- Explore the financials of https://doi.org/10.1016%2Fj.biocel.2014.06.007
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24953561's total income per month
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Wortmannin%20potentiates%20the%20combined%20effect%20of%20etoposide%20and%20cisplatin%20in%20human%20glioma%20cells&journal=Int.%20J.%20Biochem.%20Cell.%20Biol.&doi=10.1016%2Fj.biocel.2014.06.007&volume=53&pages=423-431&publication_year=2014&author=Pastwa%2CE
- What's the financial gain of https://doi.org/10.1146%2Fannurev-genet-102808-114910?
- Income figures for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19653858
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831538 pull in?
- http://scholar.google.com/scholar_lookup?&title=Regulation%20mechanisms%20and%20signaling%20pathways%20of%20autophagy&journal=Annu.%20Rev.%20Genet.&doi=10.1146%2Fannurev-genet-102808-114910&volume=43&pages=67-93&publication_year=2009&author=He%2CC&author=Klionsky%2CDJ's revenue stream
- What is the monthly revenue of https://doi.org/10.1016%2Fj.febslet.2010.01.017?
- Financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20083114
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846630 pull in?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=MTOR%20regulation%20of%20autophagy&journal=FEBS%20Lett.&doi=10.1016%2Fj.febslet.2010.01.017&volume=584&pages=1287-1295&publication_year=2010&author=Jung%2CCH&author=Ro%2CSH&author=Cao%2CJ&author=Otto%2CNM&author=Kim%20Do-Hyung%2CDH?
- What are the earnings of https://doi.org/10.1158%2F1535-7163.MCT-12-0129?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Breakdown%20of%20the%20FLT3-ITD%20%2F%20STAT5%20axis%20and%20synergistic%20apoptosis%20induction%20by%20the%20histone%20deacetylase%20inhibitor%20panobinostat%20and%20FLT3-specific%20inhibitors&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-12-0129&volume=412&pages=2373-2384&publication_year=2012&author=Pietschmann%2CK?
- How much does https://doi.org/10.1038%2Fleu.2012.96 pull in monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Using%20combination%20therapy%20to%20override%20stromal-mediated%20chemoresistance%20in%20mutant%20FLT3-positive%20AML%3A%20synergism%20between%20FLT3%20inhibitors%2C%20dasatinib%20%2F%20multi-targeted%20inhibitors%20and%20JAK%20inhibitors&journal=Leukemia&doi=10.1038%2Fleu.2012.96&volume=25&pages=2233-2244&publication_year=2012&author=Weisberg%2CE make?
- How much profit does https://doi.org/10.1038%2Fnbt.2284 make?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22781697?
- How much money does http://scholar.google.com/scholar_lookup?&title=Combinatorial%20drug%20therapy%20for%20cancer%20in%20the%20post-genomic%20era&journal=Nat.%20Biotechnol.&doi=10.1038%2Fnbt.2284&volume=30&pages=679-692&publication_year=2012&author=Al-Lazikani%2CB&author=Banerji%2CU&author=Workman%2CP make?
- Financial intake of https://doi.org/10.1158%2F1535-7163.MCT-14-0258
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=BET%20protein%20antagonist%20JQ1%20is%20synergistically%20lethal%20with%20FLT3%20tyrosine%20kinase%20inhibitor%20%28TKI%29%20and%20overcomes%20resistance%20to%20FLT3-TKI%20in%20AML%20cells%20expressing%20FLT-ITD&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-14-0258&volume=13&pages=2315-2327&publication_year=2014&author=Warren%2CF
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7929357 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=Selective%20binding%20and%20uptake%20of%20ribonuclease%20a%20and%20glyceraldehyde-3-phosphate%20dehydrogenase%20by%20isolated%20rat%20liver%20lysosomes&journal=J.%20Biol.%20Chem.&volume=269&pages=26374-26380&publication_year=1994&author=Cuervo%2CAM&author=Terlecky%2CSR&author=Dice%2CJF&author=Knecht%2CE pull in?
- How profitable is https://doi.org/10.1101%2Fgad.220897.113?
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23913924?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744729 pull in monthly?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Chaperone-mediated%20autophagy%20degrades%20mutant%20p53&journal=Genes%20Dev.&doi=10.1101%2Fgad.220897.113&volume=27&pages=1718-1730&publication_year=2013&author=Vakifahmetoglu-Norberg%2CH?
- How profitable is https://doi.org/10.1091%2Fmbc.E07-11-1155?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Constitutive%20activation%20of%20chaperone-mediated%20autophagy%20in%20cells%20with%20impaired%20macroautophagy&journal=Mol.%20Biol.%20Cell.&doi=10.1091%2Fmbc.E07-11-1155&volume=19&pages=308-317&publication_year=2008&author=Kaushik%2CS&author=Massey%2CAC&author=Mizushima%2CN&author=Cuervo%2CAM bring in?
- What's the financial intake of https://doi.org/10.1042%2FBST20130126?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24256241 is on a monthly basis
- What's http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000258's gross income?
- Get to know http://scholar.google.com/scholar_lookup?&title=Chaperone-mediated%20autophagy%3A%20dedicated%20saviour%20and%20unfortunate%20victim%20in%20the%20neurodegeneration%20arena&journal=Biochem.%20Soc.%20Trans.&doi=10.1042%2FBST20130126&volume=41&pages=1483-1488&publication_year=2013&author=Schneider%2CJL&author=Cuervo%2CAM's earnings
- How much does https://doi.org/10.1016%2Fj.febslet.2009.12.025 pull in monthly?
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20026330
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Chaperone-mediated%20autophagy%20in%20health%20and%20disease&journal=FEBS%20Lett.&doi=10.1016%2Fj.febslet.2009.12.025&volume=584&pages=1399-1404&publication_year=2010&author=Kon%2CM&author=Cuervo%2CAM is on a monthly basis
- Discover the revenue of https://doi.org/10.1073%2Fpnas.0507436103
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16585521
- What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458654?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Consequences%20of%20the%20selective%20blockage%20of%20chaperone-mediated%20autophagy&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0507436103&volume=103&pages=5805-5810&publication_year=2006&author=Massey%2CAC&author=Kaushik%2CS&author=Sovak%2CG&author=Kiffin%2CR&author=Cuervo%2CAM generate?
- How much money does https://doi.org/10.1080%2F15548627.2015.1106666 make?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26577179's revenue stream
- Profit of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835192
- How much does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20chaperone-mediated%20autophagy%20as%20a%20potential%20anticancer%20therapy&journal=Autophagy&doi=10.1080%2F15548627.2015.1106666&volume=11&pages=2370-2371&publication_year=2015&author=Galan-Acosta%2CL&author=Xia%2CH&author=Yuan%2CJ&author=Vakifahmetoglu-Norberg%2CH pull in?
- How much profit does https://doi.org/10.1080%2F15548627.2017.1293767 generate?
- Financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=28410006
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Chaperone-mediated%20autophagy%20prevents%20cellular%20transformation%20by%20regulating%20MYC%20proteasomal%20degradation&journal=Autophagy&doi=10.1080%2F15548627.2017.1293767&volume=13&pages=928-940&publication_year=2017&author=Gomes%2CLR&author=Menck%2CCFM&author=Cuervo%2CAM generate?
- How much does https://doi.org/10.1080%2F15548627.2015.1023982 rake in every month?
- Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25906440 earns monthly
- How much income does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502663 have?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Modification%20of%20BECN1%20by%20ISG15%20plays%20a%20crucial%20role%20in%20autophagy%20regulation%20by%20type%20I%20IFN%20%2F%20interferon%20Modi%20fi%20cation%20of%20BECN1%20by%20ISG15%20plays%20a%20crucial%20role%20in%20autophagy%20regulation%20by%20type%20I%20IFN%20%2F%20interferon&journal=Autophagy&doi=10.1080%2F15548627.2015.1023982&volume=11&pages=617-628&publication_year=2015&author=Xu%2CD?
- https://doi.org/10.1038%2Fnprot.2006.179's revenue stream
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17406391 generate?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Sulforhodamine%20B%20colorimetric%20assay%20for%20cytotoxicity%20screening&journal=Nat.%20Protoc.&doi=10.1038%2Fnprot.2006.179&volume=1&pages=1112-1116&publication_year=2006&author=Vichai%2CV&author=Kirtikara%2CK generate?
- https://link.springer.com/doi/10.1186/1423-0127-18-44's revenue stream
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21689407 rake in every month?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141632 gross monthly?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Specific%20microtubule-depolymerizing%20agents%20augment%20efficacy%20of%20dendritic%20cell-based%20cancer%20vaccines&journal=J.%20Biomed.%20Sci.&doi=10.1186%2F1423-0127-18-44&volume=18&publication_year=2011&author=Wen%2CCC bring in?
- What's the monthly income of https://citation-needed.springer.com/v2/references/10.1038/s41419-017-0170-9?format=refman&flavour=references?
- What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Amanda%20Tomie%20Ouchida?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Amanda%20Tomie%20Ouchida%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yingbo%20Li generate?
- What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yingbo%20Li%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- See how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jiefei%20Geng makes per month
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jiefei%20Geng%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ayaz%20Najafov each month?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ayaz%20Najafov%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Dimitry%20Ofengeim?
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Dimitry%20Ofengeim%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xiaoxiao%20Sun earning monthly?
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xiaoxiao%20Sun%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qiang%20Yu?
- How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qiang%20Yu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Junying%20Yuan generate?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Junying%20Yuan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
- Learn about the earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_MOESM1_ESM.pdf
- Learn about the earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fs41419-017-0170-9/MediaObjects/41419_2017_170_MOESM2_ESM.docx
- Explore the financials of http://creativecommons.org/licenses/by/4.0/
- What's the financial gain of https://s100.copyright.com/AppDispatchServlet?title=Synergistic%20effect%20of%20a%20novel%20autophagy%20inhibitor%20and%20Quizartinib%20enhances%20cancer%20cell%20death&author=Amanda%20Tomie%20Ouchida%20et%20al&contentID=10.1038%2Fs41419-017-0170-9©right=The%20Author%28s%29&publication=2041-4889&publicationDate=2018-01-26&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY?
- How much money does https://crossmark.crossref.org/dialog/?doi=10.1038/s41419-017-0170-9 make?
- What's the income generated by https://citation-needed.springer.com/v2/references/10.1038/s41419-017-0170-9?format=refman&flavour=citation each month?
- Discover the revenue of https://doi.org/10.1186/s40364-024-00600-1
- How much does https://doi.org/10.1038/s41420-024-01823-9 generate monthly?
- How much money does https://doi.org/10.1038/s41416-023-02148-7 generate?
- Get to know what's the income of https://doi.org/10.1186/s13045-022-01262-y
- Explore the financials of https://doi.org/10.1038/s41392-022-01110-y
- How much does https://www.protocols.io/ gross monthly?
- https://www.natureindex.com/'s revenue stream
- How much does http://www.naturechina.com rake in every month?
- Learn about the earnings of https://www.natureasia.com/ja-jp
Analytics and Tracking {๐}
- Google Tag Manager
Libraries {๐}
- Particles.js
- Prism.js
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {๐ฆ}
- Crossref