
PMC . NCBI . NLM . NIH . GOV {
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Title:
Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis - PMC
Description:
Rheumatoid arthritis (RA) is the most common inflammatory arthritis and exhibits genetic overlap with other autoimmune and inflammatory disorders. Although predominant associations with the HLA-DRB1 locus have been known for decades, recent data ...
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27 years and 9 months (reg. 1997-10-02).
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Keywords {🔍}
arthritis, doi, google, scholar, pubmed, rheumatoid, pmc, article, free, risk, alleles, acpa, genetic, disease, rheum, study, hla, cell, association, patients, drb, genet, studies, variants, susceptibility, reported, data, ptpn, van, loci, cells, gene, genes, effects, populations, smoking, heritability, citrullinated, associations, hladrb, gwas, ann, development, antibodies, dis, nat, genomewide, autoimmune, clinical, amino,
Topics {✒️}
krn/i-ag7 mouse model anti-citrullinated peptide/protein antibody anti-citrullinated protein antibody-positive anti-citrullinated protein/peptide antibodies anti-α-enolase cep1 antibodies large-scale single-nucleotide polymorphism anti-cyclic citrullinated peptide anti-tnf-α therapy induces multiple-ethnicity gwas meta-analysis anti-citrullinated protein antibodies anti-carbamylated protein antibodies b-cell alloantigen drw4 genome-wide study combined pmc beta search longer-term clinical outcomes cyclic citrullinated peptide de vries-bouwstra jk genome-wide association analysis genome-wide association study genome-wide association studies c57bl/6-lpr/lpr mice missense single-nucleotide polymorphism hla-dr4 subtype frequencies autoantibody-negative rheumatoid arthritis called broad-sense heritability nested case-control study cell type-specific mark cell-specific protein phenotypes genotype-selectable human bioresource autoantibody-positive rheumatoid arthritis sophisticated sequencing-based approaches called narrow-sense heritability dw4-dependent risk factor cell type-specific elements citrullinated α-enolase citrullinated vimentin antibody citrullinated fibrinogen antibody nationwide case-control study van der linden anticitrullinated protein antibodies strong gene-environment effect anti-tnf drug response acpa-negative ra consists common immune-mediated arthritis hibag—hla genotype imputation professional antigen-presenting cells cyclic citrullinated peptides van der woude van der heijde tumor necrosis factor
Questions {❓}
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