
PMC . NCBI . NLM . NIH . GOV {
}
Title:
αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin - PMC
Description:
Upon binding to the extracellular matrix protein, fibronectin, αV-class and α5β1 integrins trigger the recruitment of large protein assemblies and strengthen cell adhesion. Both integrin classes have been functionally specified, however their ...
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27 years and 9 months (reg. 1997-10-02).
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Custom-built
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🌠 Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {🔍}
integrins, adhesion, fibroblasts, αvclass, cell, pkoαvβ, integrin, doi, google, scholar, pubmed, fibroblast, binding, fig, fniii, pmc, supplementary, article, crosstalk, contact, free, force, biol, talin, min, scfs, cantilever, time, cantilevers, signalling, experiments, strengthen, data, kindlin, substrate, pkoβ, usa, fibronectin, early, attached, tirf, cona, bind, arp, compared, pkoαv, buffer, results, forces, single,
Topics {✒️}
ɛ=fpko-αv/β1+fpko−fpko-αv−fpko-β1 pko-αv/β1 lifeact-mcherry paxillin-gfp pko-β1 lifeact-mcherry paxillin-gfp6 pko-αv lifeact-mcherry paxillin-gfp vn-attached pko-αv/β1 fibroblasts cona-attached pko-αv/β1 fibroblasts vn-stimulated pko-αv/β1 fibroblasts lifeact-mcherry expressing pko-αvβ1 icap-1-dependent beta1-integrin affinity pko-αv/β1 fibroblasts6 demonstrate tailed mann–whitney u-tests fpko-αv/β1+fpko fpko-αv+fpko-β1 pko-αv/β1 fibroblasts seeded attached pko-αv/β1 fibroblasts pko-αv/β1 fibroblasts attached stimulate pko-αv/β1 fibroblasts stimulated pko-αv/β1 fibroblasts unperturbed pko-αv/β1 fibroblasts prevent pko-αv/β1 fibroblasts pko-αv/β1 fibroblasts induced pko-αv/β1 fibroblasts treated pko-αv/β1 fibroblasts adhering αv-class integrin-mediated outcompeting unperturbed pko-αv/β1 fibroblast stated pko-αv/β1 fibroblasts rac1/wave/arp2/3 pathway6 regulate vn-bound αv-class integrins20 rac1/wave/arp2/3 pathway6 affects tripeptide sequence arg-gly-asp [google scholar] friedrichs fn-engaged αv-class integrins stimulated pko-αv/β1 tailed mann–whitney tests rac1/wave/arp2/3 pathways pko-αv/β1 fibroblasts anti-β1 integrin antibody alpha2beta1 integrin-mediated adhesion �differential integrin-dependent adhesion' s-trity-l-cysteine s-trityl-l-cysteine cona-attached pko-αv pko-β1 fibroblasts established αv-class integrin signalling αv-class integrins contribute unoccupied αv-class integrins αv-class integrins separate affecting αv-class integrins activated αv-class integrins αv-class integrins engaged
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