PMC . NCBI . NLM . NIH . GOV {
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We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3882442/.
Title:
Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis - PMC
Description:
Recent studies indicate that metabolic oxidative stress, autophagy, and inflammation are hallmarks of nonalcoholic steatohepatitis (NASH) progression. However, the molecular mechanisms that link these important events in NASH remain unclear. In this ...
Website Age:
27 years and 9 months (reg. 1997-10-02).
Title:
Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis - PMC
Description:
Recent studies indicate that metabolic oxidative stress, autophagy, and inflammation are hallmarks of nonalcoholic steatohepatitis (NASH) progression. However, the molecular mechanisms that link these important events in NASH remain unclear. In this ...
Website Age:
27 years and 9 months (reg. 1997-10-02).
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Keywords {🔍}
mice, receptor, autophagy, nash, fig, group, liver, diet, protein, diobdcm, doi, oxidative, lampa, pubmed, google, scholar, stress, compared, dio, levels, mcd, pmc, metabolic, cype, lcb, free, inflammation, highfat, article, injury, lysosomal, toxin, bdcm, expression, decreased, increased, membrane, genedeleted, receptordeleted, steatohepatitic, study, gene, analysis, significant, nonalcoholic, proteins, groups, hsc, mrna, fed,
Topics {✒️}
5-dimethyl-1-pyrroline n-oxide-nitrone adducts 5-dimethyl-1-pyrroline n-oxide chaperone-mediated autophagy-related proteins mcd-diet-fed group compared mcd-diet-fed mice compared mcd-diet-fed groups compared olanzapine-induced metabolic toxicity mcd-diet-fed wild-type p2x7 gene-deleted mice p2x7 receptor-deleted group mcd-diet-treated mice compared p2x7 receptor-deleted mice quantitative real-time pcr gene-specific knockout mice mcd-diet-fed livers compared confocal microscopy based-immunolocalization carbon tetrachloride-mediated steatohepatitis pmc beta search cyp2e1-deleted mice fed custom diet-induced obesity c57bl/6j background fed induce chaperone-mediated autophagy picro-sirius red staining wild-type mice fed protein radical formation paraffin-embedded liver tissue 5-μm-thick tissue sections pmc copyright notice p2x7 receptor-mediated release late autophagy-related proteins mcd-diet-fed group wild-type mice treated p2x7-dependent inflammatory functions mcd-diet-fed mice diet-induced nash group mcd-treated group compared protein free radicals mcd-diet-fed groups mcs-diet fed group mcs-diet-fed group early autophagy-inducing genes p2x7 receptor modulates autophagy-related protein 2a mcs-diet-fed mice obesity-induced steatohepatitic injury high-fat diet+bdcm mcs-diet-fed groups ccl4-mediated nash model oxidative stress induced p2x7 receptor gene
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