
PMC . NCBI . NLM . NIH . GOV {
}
Title:
Surface-Based Protein Binding Pocket Similarity - PMC
Description:
Protein similarity comparisons may be made on a local or global basis and may consider sequence information or differing levels of structural information. We present a local 3D method that compares protein binding site surfaces in full atomic ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Matching Content Categories {π}
- Science
- Fitness & Wellness
- Books & Literature
Content Management System {π}
What CMS is pmc.ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Pmc.ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of pmc.ncbi.nlm.nih.gov audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Pmc.ncbi.nlm.nih.gov Make Money? {πΈ}
We're unsure if the website is profiting.
Not all websites focus on profit; some are designed to educate, connect people, or share useful tools. People create websites for numerous reasons. And this could be one such example. Pmc.ncbi.nlm.nih.gov might have a hidden revenue stream, but it's not something we can detect.
Keywords {π}
protein, similarity, proteins, binding, ligand, set, structures, pocket, doi, ligands, sequence, figure, psim, alignment, based, kinases, structure, site, approach, methods, sites, pubmed, google, scholar, local, comparison, sets, atp, comparisons, motifs, bound, structural, data, method, similar, similarities, surface, kahraman, kinase, pmc, related, motif, results, yielded, molecules, significant, molecular, function, small, differences,
Topics {βοΈ}
alignment-free ultra-high-throughput comparison pmc beta search negatively charged surface local gradient-based optimization gradient-based local optimization ligand-based structural hypotheses atom-cloud comparison method genome-based drug discovery full atomic detail integrated sequence-structure analysis nucleotide head free atp-binding data set dimensional structure-based method common binding mode blue represent similarities redesigned web site comprising multiple subsets binding site location surflex-psim approach yielded heuristic search approaches qualitatively complementary information yield quantitative information divergent human kinases green sticks correspond primary pdb files generally highly similar binding sites based dimensional protein folds protein binding sites local surface similarity greater variability exists unified statistical model trends biochem sci smallest binding sites phosphate tail region hinge-binding motifs16 binding site scope binding site comparisons license information pmcid include sidechain information surface epitope preservation local pocket similarity ligand binding preferences pseudo-kinase stradΞ± multiple chemotypes targeting protein binding pockets standard desktop hardware ligand binding data binding pockets proximal protein pocket similarity
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- ns-cloud-e1.googledomains.com
- ns-cloud-e2.googledomains.com
- ns-cloud-e3.googledomains.com
- ns-cloud-e4.googledomains.com
CDN Services {π¦}
- Ncbi