
PMC . NCBI . NLM . NIH . GOV {
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Title:
MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis - PMC
Description:
MicroRNAs (miRNAs) are critical regulators of transcriptional and post-transcriptional gene silencing, which are involved in multiple developmental processes in many organisms. Apart from miRNAs, mouse germ cells express another type of small RNA, ...
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Keywords {🔍}
doi, pgcs, cells, expression, dicercko, pubmed, google, scholar, figure, mirnas, dicer, cell, mirna, spermatogenesis, spermatogonia, germ, development, proliferation, analysis, cluster, levels, pmc, mouse, testis, pcr, article, neonatal, males, tif, male, retrotransposons, free, control, progeny, expressed, number, line, data, gene, role, realtime, silencing, microrna, small, ago, showed, allele, dev, mice, results,
Topics {✒️}
real-time pcr analyses pmc beta search oct4δpe-gfp reporter gene oct4-gfp transgenic mice dicer-mediated mirna machinery post-transcriptional gene silencing real-time pcr showed real-time pcr analysis mouse vasa-homologue protein stem-loop rt-pcr mouse piwi-related genes conditional dicer-knockout mice dicerf/+ tnap-cre males dicerf/+ tnap-cre fetuses cre-mediated dicer-excision cre-mediated dicer excision es cell-specific cluster retroposon-derived 24-26-nucleotide rnas conditional argonaute2-deficient mice locus encoding mir-141/200c mouse piwi-family proteins es cell-specific mirnas publisher site pdf dicer-deficient es cells dicer-mediated mirna biogenesis wild-type females showed oct-4/green fluorescent protein real-time pcr mirna-specific forward primers bisulfite sequencing profiles real-time quantification mirna-processing enzyme dicer stem-loop structure license information pmcid embryonic stem cells piwi-family proteins play express cre preferentially piwi-interacting rna cell cycle progression stem cell population cre-mediated recombination dicerf/+ tnap-cre intact floxed allele piwi-interacting rnas similar seed sequence human lung cancers discussion characteristic pattern cre transgenic mouse pten promotes proliferation tnap-cre mice
Questions {❓}
- Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
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