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Title:
DeepPicker: A deep learning approach for fully automated particle picking in cryo-EM - ScienceDirect
Description:
Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bott…
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Keywords {🔍}
particle, picking, cryoem, learning, data, automated, deep, micrographs, struct, biol, particles, selection, approaches, fully, singleparticle, training, electron, biology, approach, analysis, human, microscopy, structure, automatic, structural, volume, based, maps, process, machine, cryoelectron, journal, issue, deeppicker, step, pipeline, number, manual, cheng, complex, zhao, chen, model, detection, abstract, framework, scheme, determination, program, molecular,
Topics {✒️}
high-resolution cryo-em studies single-particle electron cryo-microscopy uk/pdbe/emdb/empiar/ yifan cheng cryoem-cloud-tools cheng single-particle cryo-em cryo-em structure determination global b-factor correction recently-published cryo-em data real cryo-em data automated cryo-em pipeline amit singer real-time manage cryo-em jobs cryo-electron microscopy proc n-ethylmaleimide sensitive factor sars-cov-2 rna polymerase large-scale data analysis k2 electron-counting camera single-particle electron cryomicroscopy large-scale training data single-particle data analysis perform automatic post-processing partially-automated particle selection single-particle selection system extracted cross-molecule features numerous automatic particle pickers support vector machine-based semi-automated particle selection semi-supervised machine learning cross-molecule training scheme low-contrast electron micrographs cross-molecule training strategy common abstract representation fully automated pipeline cryo-electron microscopy high-quality reference particles cross-correlation similarity measure cryo-em data cryo-em maps introduction recent advance section snippets previously-determined molecular structures nature methods deepre single-particle analysis protein structure modeling cross-molecule data automatic particle detection snare complex nature fully automated scheme molecular electron microscopy facilitate particle selection
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