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Title:
Standardized Sequence and Structure Analysis of Antibody Using IMGT® | SpringerLink
Description:
Standardized sequence and structure analysis of antibody using IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org), allows to bridge, for the first time, the gap between antibody sequences and three-dimensional (3D) structures....
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Keywords {🔍}
lefranc, google, scholar, imgt, article, pubmed, cas, giudicelli, analysis, antibody, immunoglobulin, cell, immunogenetics, information, receptor, kaas, standardized, sequence, system, engineering, protocol, duroux, international, nucl, acids, res, domains, structure, springer, protocols, nomenclature, unique, numbering, ginestoux, immunol, chaume, privacy, cookies, content, publish, ehrenmann, imgtontology, immunoinformatics, tools, chapter, dev, comp, gene, database, human,
Topics {✒️}
véronique giudicelli & marie-paule lefranc imgt/collier-de-perles tools month download article/chapter standardized sequence–structure representations de la recherche imgt/v-quest system mhc groove g-domain amino acid sequence marie-paule lefranc chronic lymphocytic leukemia integrated imgt/junctionanalysis software formal imgt-ontology paradigm colliers de perles privacy choices/manage cookies yousfi monod device instant download tr standardized v cell receptors report springer protocols handbooks chronic lymphocytic leukaemia région languedoc-roussillon rio de janeiro imgt standardized criteria imgt/v-quest 13th international congress gene-centered information cell receptor genes cell receptor repertoires wolters kluwer health 5th pcrdt quality author information authors editor information editors imgt® standardized analysis cell receptor factsbook immunogénétique moléculaire ligm journal finder publish immunogenetics sequence annotation imgt unique numbering conditions privacy policy vertebrate genome annotation imgt/gene-db imgt gene identification antibody engineering methods imgt/2dstructure-db imgt/3dstructure-db imgt/ligm-db european economic area tr cdna sequences standardized sequence mhc structural data
Questions {❓}
- Kaas Q, Ehrenmann F, Lefranc M-P (2007) IG, TR and IgSf, MHC and MhcSF: what do we learn from the IMGT Colliers de Perles?
Schema {🗺️}
ScholarlyArticle:
headline:Standardized Sequence and Structure Analysis of Antibody Using IMGT®
pageEnd:31
pageStart:11
image:https://media.springernature.com/w153/springer-static/cover/book/978-3-642-01147-4.jpg
genre:
Springer Protocols
isPartOf:
name:Antibody Engineering
isbn:
978-3-642-01147-4
978-3-642-01146-7
type:Book
publisher:
name:Springer Berlin Heidelberg
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:François Ehrenmann
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
type:Person
name:Patrice Duroux
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
type:Person
name:Véronique Giudicelli
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
type:Person
name:Marie-Paule Lefranc
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
email:[email protected]
type:Person
keywords:Versus Domain, Contact Analysis, Synthesis View, Result Display, International Nonproprietary Name
description:Standardized sequence and structure analysis of antibody using IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org), allows to bridge, for the first time, the gap between antibody sequences and three-dimensional (3D) structures. This is achieved through the IMGT Scientific chart rules, based on IMGT-ONTOLOGY. IMGT® is the international reference for immunogenetics and immunoinformatics, and its standards (IMGT nomenclature and labels and IMGT unique numbering) are particularly useful for antibody humanization and evaluation of immunogenicity. In IMGT®, the antibody analysis from nucleotide sequence to 2D structure is supported by the widely used IMGT/V-QUEST system and the integrated IMGT/JunctionAnalysis software. The IMGT® approach from amino acid sequence to 3D structure is supported by the IMGT/DomainDisplay, IMGT/DomainGapAlign and IMGT/Collier-de-Perles tools, by some important features of IMGT/2Dstructure-DB, for antibodies for which 3D structures are not yet available (INN entries) and IMGT/3Dstructure-DB and associated tools, for crystallized antibodies (Contact analysis, IMGT/StructuralQuery, IMGT/DomainSuperimpose).
datePublished:2010
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Book:
name:Antibody Engineering
isbn:
978-3-642-01147-4
978-3-642-01146-7
Organization:
name:Springer Berlin Heidelberg
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:François Ehrenmann
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
name:Patrice Duroux
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
name:Véronique Giudicelli
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
name:Marie-Paule Lefranc
affiliation:
name:Université Montpellier 2, Institut de Génétique Humaine
address:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
name:IMGT®, the international ImMunoGeneTics Information System®, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Université Montpellier 2, Institut de Génétique Humaine, Montpellier Cedex 5, France
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