We are analyzing https://link.springer.com/chapter/10.1007/978-3-642-59953-8_8.

Title:
Functions of Tie1 and Tie2 Receptor Tyrosine Kinases in Vascular Development | SpringerLink
Description:
Vascularization of the mouse embryo is accomplished via the collaboration of two major cellular processes. Differentiation of vascular endothelial cells de novo from their precursors, called the angioblasts, has been termed vasculogenesis (Risau 1997). Somewhat...
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Science
Technology & Computing

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 8,170,236 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

Not all websites are made for profit; some exist to inform or educate users. Or any other reason why people make websites. And this might be the case. Link.springer.com might be cashing in, but we can't detect the method they're using.

Keywords {🔍}

google, scholar, pubmed, cas, article, receptor, tyrosine, tie, kinase, endothelial, vascular, cell, cells, development, expression, alitalo, angiogenesis, growth, chapter, dumont, protein, partanen, nature, vasculogenesis, kinases, blood, oncogene, mouse, expressed, genes, rossant, breitman, risau, pardanaud, embryonic, sato, privacy, cookies, content, information, publish, embryo, mesoderm, download, korhonen, leukemia, human, factor, sci, usa,

Topics {✒️}

inositol polyphosphate-5-phosphatase activity month download article/chapter receptor tyrosine kinases receptor tyrosine kinase secretion-trap expression cloning c-etsl proto-oncogene vascular growth factors van der zee tie gene promoter dok-related docking protein transcription factor expressed privacy choices/manage cookies megakaryocyte-specific genes endothelial cell lineage vascular endothelial cells constitutively tyrosine-phosphorylated device instant download tie2 receptor expression angiogenic capillary growth growth factor distinct endothelial lineages promoter implicates gata protein module implicated vascular dysmorphogenesis caused endothelial cell survival endothelial cell precursors insulin receptor substrate-1 vascular system defects hematopoietic stem cells tyrosine kinase leukemia cell lines european economic area rat pulmonary microcirculation postnatal rat lung targeted null mutations continuous labelling studies epithelio-mesenchymal specificity mount sinai hospital distinct rat genes journal finder publish download preview pdf abnormal mesoderm patterning cells step backward growth factors mouse embryos mutant adult transgenic mice conditions privacy policy primitive vascular network directed migration multiple chromosomal translocations

Schema {🗺️}

ScholarlyArticle:
      headline:Functions of Tie1 and Tie2 Receptor Tyrosine Kinases in Vascular Development
      pageEnd:172
      pageStart:159
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-642-59953-8.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Vascular Growth Factors and Angiogenesis
         isbn:
            978-3-642-59953-8
            978-3-642-64195-4
         type:Book
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:J. Partanen
            affiliation:
                  name:Mount Sinai Hospital
                  address:
                     name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D. J. Dumont
            affiliation:
                  name:University of Toronto
                  address:
                     name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Receptor Tyrosine Kinase, Vascular Development, Endothelial Cell Lineage, Tie2 Receptor, Vascular Defect
      description:Vascularization of the mouse embryo is accomplished via the collaboration of two major cellular processes. Differentiation of vascular endothelial cells de novo from their precursors, called the angioblasts, has been termed vasculogenesis (Risau 1997). Somewhat confusingly, the term vasculogenesis has also been used in a broader sense, covering all aspects of vascular development (Dumont et al. 1994; Noden 1991; Sherer 1991; Wilting and Christ 1996). Subsequent expansion of the endothelium by remodelling, migration and proliferation is called angiogenesis. Vasculogenesis is known to occur intraembryonically within the splanchnopleural and paraxial mesoderm, as well as extraembryonically in the yolk sac mesoderm, and is responsible for laying down the primitive vascular network (Pardanaud et al. 1996; Wilting and Christ 1996). Vasculogenesis is characterized by angioblast differentiation and by either the immediate aggregation of angioblast cells to give rise to endothelium, or the directed migration of these cells through the embryo to segregate eventually into vascular cords. Interestingly, angioblasts appear to have different characteristics depending on their site of origin (Pardanaud et al. 1996). Vasculogenesis both in the yolk sac and in the splanchnic mesoderm appears closely linked to haemangioblast (Pardanaud et al. 1989; Shalaby et al. 1995, 1997).
      datePublished:1999
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
      context:https://schema.org
Book:
      name:Vascular Growth Factors and Angiogenesis
      isbn:
         978-3-642-59953-8
         978-3-642-64195-4
Organization:
      name:Springer Berlin Heidelberg
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Mount Sinai Hospital
      address:
         name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
         type:PostalAddress
      name:University of Toronto
      address:
         name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:J. Partanen
      affiliation:
            name:Mount Sinai Hospital
            address:
               name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
               type:PostalAddress
            type:Organization
      name:D. J. Dumont
      affiliation:
            name:University of Toronto
            address:
               name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
      name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(198)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js

CDN Services {📦}

Pbgrd

4.26s.

LINK . SPRINGER . COM {}