We are analyzing https://link.springer.com/chapter/10.1007/978-3-319-20819-0_7.

Title:
An Immune Effector System in the Protochordate Gut Sheds Light on Fundamental Aspects of Vertebrate Immunity | SpringerLink
Description:
A variety of germline and somatic immune mechanisms have evolved in vertebrate and invertebrate species to detect a wide array of pathogenic invaders. The gut is a particularly significant site in terms of distinguishing pathogens from potentially beneficial...
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Keywords {🔍}

pubmed, google, scholar, article, cas, litman, immune, central, chapter, gut, dishaw, immunol, cannon, usa, santis, pinto, variable, interactions, system, vertebrate, proteins, haire, privacy, cookies, content, information, publish, ciona, role, genome, receptor, nat, mueller, springer, research, search, somatic, adaptations, protochordate, immunity, liberti, rosaria, intestinalis, marine, regioncontaining, chitinbinding, vcbps, development, evolution, nature,

Topics {✒️}

month download article/chapter chapter pathogen-host interactions commensal host-bacterial relationships filter-feeding marine protochordate cell-independent iga synthesis immunoglobulin-type variable region pathogen-host interactions maria rosaria pinto host gut-bacteria interactions immune-related proteins expressed dishaw lj host-microbe interactions privacy choices/manage cookies immune-type receptor rosaria de santis medicine sponsored research innate immune receptors flores-torres ja device instant download invertebrate antigen receptor rich microbial communities european economic area human secretory immunoglobulin immunoglobulin heavy chains immune-directed support secreted immune effectors potentially beneficial microbes possesses variable region iga-producing immunocytes closest living relatives basal chordate model ascidian halocynthia roretzii ascidian tadpole larva marine viral assemblages south florida college editor information editors genome size distributions de jong pj de bruyn ka immune effector system vertebrate immune system adaptive immune regulation conditions privacy policy joining region genes gibson-brown jj adaptive immune system chitin-binding proteins south florida st invertebrate immune diversity accepting optional cookies

Questions {❓}

Lee YK, Mazmanian SK (2010) Has the microbiota played a critical role in the evolution of the adaptive immune system?
The Gut Microbiome and Its Marriage to the Immune System: Can We Change It All?

Schema {🗺️}

ScholarlyArticle:
      headline:An Immune Effector System in the Protochordate Gut Sheds Light on Fundamental Aspects of Vertebrate Immunity
      pageEnd:173
      pageStart:159
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-319-20819-0.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
         isbn:
            978-3-319-20819-0
            978-3-319-20818-3
         type:Book
      publisher:
         name:Springer International Publishing
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Assunta Liberti
            affiliation:
                  name:Stazione Zoologica Anton Dohrn
                  address:
                     name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Brittany Leigh
            affiliation:
                  name:University of South Florida St. Petersburg
                  address:
                     name:Department of Marine Sciences, University of South Florida St. Petersburg, St Petersburg, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rosaria De Santis
            affiliation:
                  name:Stazione Zoologica Anton Dohrn
                  address:
                     name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maria Rosaria Pinto
            affiliation:
                  name:Stazione Zoologica Anton Dohrn
                  address:
                     name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:John P. Cannon
            affiliation:
                  name:University of South Florida College of Medicine
                  address:
                     name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Larry J. Dishaw
            affiliation:
                  name:University of South Florida College of Medicine
                  address:
                     name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gary W. Litman
            affiliation:
                  name:University of South Florida College of Medicine
                  address:
                     name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Adaptive Immune System, Versus Domain, Beneficial Microbe, Stomach Lumen, Frequent Indels
      description:A variety of germline and somatic immune mechanisms have evolved in vertebrate and invertebrate species to detect a wide array of pathogenic invaders. The gut is a particularly significant site in terms of distinguishing pathogens from potentially beneficial microbes. Ciona intestinalis, a filter-feeding marine protochordate that is ancestral to the vertebrate form, possesses variable region-containing chitin-binding proteins (VCBPs), a family of innate immune receptors, which recognize bacteria through an immunoglobulin-type variable region. The manner in which VCBPs mediate immune recognition appears to be related to the development and bacterial colonization of the gut, and it is likely that these molecules are critical elements in achieving overall immune and physiological homeostasis.
      datePublished:2015
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Book:
      name:Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
      isbn:
         978-3-319-20819-0
         978-3-319-20818-3
Organization:
      name:Springer International Publishing
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Stazione Zoologica Anton Dohrn
      address:
         name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
         type:PostalAddress
      name:University of South Florida St. Petersburg
      address:
         name:Department of Marine Sciences, University of South Florida St. Petersburg, St Petersburg, USA
         type:PostalAddress
      name:Stazione Zoologica Anton Dohrn
      address:
         name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
         type:PostalAddress
      name:Stazione Zoologica Anton Dohrn
      address:
         name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
         type:PostalAddress
      name:University of South Florida College of Medicine
      address:
         name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
         type:PostalAddress
      name:University of South Florida College of Medicine
      address:
         name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
         type:PostalAddress
      name:University of South Florida College of Medicine
      address:
         name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Assunta Liberti
      affiliation:
            name:Stazione Zoologica Anton Dohrn
            address:
               name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
               type:PostalAddress
            type:Organization
      name:Brittany Leigh
      affiliation:
            name:University of South Florida St. Petersburg
            address:
               name:Department of Marine Sciences, University of South Florida St. Petersburg, St Petersburg, USA
               type:PostalAddress
            type:Organization
      name:Rosaria De Santis
      affiliation:
            name:Stazione Zoologica Anton Dohrn
            address:
               name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
               type:PostalAddress
            type:Organization
      name:Maria Rosaria Pinto
      affiliation:
            name:Stazione Zoologica Anton Dohrn
            address:
               name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
               type:PostalAddress
            type:Organization
      name:John P. Cannon
      affiliation:
            name:University of South Florida College of Medicine
            address:
               name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
               type:PostalAddress
            type:Organization
      name:Larry J. Dishaw
      affiliation:
            name:University of South Florida College of Medicine
            address:
               name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
               type:PostalAddress
            type:Organization
      name:Gary W. Litman
      affiliation:
            name:University of South Florida College of Medicine
            address:
               name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
      name:Department of Marine Sciences, University of South Florida St. Petersburg, St Petersburg, USA
      name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
      name:Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli, Italy
      name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
      name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
      name:Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, USA
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