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Title:
Norepinephrine Induced Growth and Expression of Virulence Associated Factors in Enterotoxigenic and Enterohemorrhagic Strains of Escherichia coli | SpringerLink
Description:
The small intestine is richly innervated by the sympathetic nervous system. High concentrations of monoamines, most notably norepinephrine, are found throughout the various intestinal layers. In order to determine whether norepinephrine is capable of influencing...
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google, scholar, cas, pubmed, article, norepinephrine, chapter, growth, coli, escherichia, lyte, content, francis, usa, privacy, cookies, information, publish, expression, virulence, factors, download, sci, state, springer, search, pathogenesis, diseases, book, bacterial, vivo, preview, brain, catecholamines, rat, university, south, dakota, usd, personal, data, log, journal, research, mechanisms, enteric, induced, enterotoxigenic, strains, arulanandam,
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month download article/chapter privacy choices/manage cookies mankato state university device instant download escherichia coli o157 sympathetic nervous system transmissible escherichia coli abundant adrenergic innervation beta adrenoreceptor mediation european economic area protein equivalent basis colostrum-fed calves gnotobiotic piglets infected vascular neuroeffector junctions naunyn-schmiedebergs arch intercellular messenger molecules gram-negative sepsis gram negative bacteria gram-negative bacteria previously called βkcoβ journal finder publish download preview pdf catecholamine induced growth catecholamine-induced growth k99 pilus adhesin norepinephrine induced growth lamb enteropathogenic strains conditions privacy policy accepting optional cookies etec strain b44 vitro results suggest estradiol-binding proteins saturable binding site infectious disease episodes rat frontal cortex intrasynaptic norepinephrine concentrations main content log influencing bacterial pathogenesis chapter lyte chapter cite escherichia coli chapter usdΒ 29 social media book series south dakota permissions reprints chapter mechanisms enteric diseases journal publish privacy policy
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ScholarlyArticle:
headline:Norepinephrine Induced Growth and Expression of Virulence Associated Factors in Enterotoxigenic and Enterohemorrhagic Strains of Escherichia coli
pageEnd:339
pageStart:331
image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4899-1828-4.jpg
genre:
Biomedical and Life Sciences
Biomedical and Life Sciences (R0)
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name:Mechanisms in the Pathogenesis of Enteric Diseases
isbn:
978-1-4899-1828-4
978-1-4899-1830-7
type:Book
publisher:
name:Springer US
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url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
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author:
name:M. Lyte
affiliation:
name:Mankato State University
address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
type:PostalAddress
type:Organization
type:Person
name:B. Arulanandam
affiliation:
name:Mankato State University
address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
type:PostalAddress
type:Organization
type:Person
name:K. Nguyen
affiliation:
name:Mankato State University
address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
type:PostalAddress
type:Organization
type:Person
name:C. Frank
affiliation:
name:Mankato State University
address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
type:PostalAddress
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type:Person
name:A. Erickson
affiliation:
name:South Dakota State University
address:
name:Department of Veterinary Science, South Dakota State University, Brookings, USA
type:PostalAddress
type:Organization
type:Person
name:D. Francis
affiliation:
name:South Dakota State University
address:
name:Department of Veterinary Science, South Dakota State University, Brookings, USA
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type:Organization
type:Person
keywords:Mandelic Acid, Monobasic Potassium Phosphate, ETEC Strain, Virulence Associate Factor, Meridian Diagnostics
description:The small intestine is richly innervated by the sympathetic nervous system. High concentrations of monoamines, most notably norepinephrine, are found throughout the various intestinal layers. In order to determine whether norepinephrine is capable of influencing bacterial pathogenesis, the growth and production of virulence factors in ETEC and EHEC were examined in a physiologically relevant medium utilizing very low initial bacterial inoculums to more closely mimic in vivo conditions. The growth of ETEC strain B44 and the production of the K99 pilus adhesin on a protein equivalent basis was greatly increased in the presence of norepinephrine. Growth of EHEC 0157:H7 was also increased in norepinephrine containing medium as well as production of SLT-I and SLT-II. The ability of norepinephrine to increase both bacterial growth and expression of virulence factors was shown to be non-nutritional in nature. Given the abundant adrenergic innervation in the small intestine, these in vitro results suggest that the neurohumoral environment of the host may play a role in bacterial growth and expression of virulence factors.
datePublished:1997
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name:Mankato State University
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name:South Dakota State University
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name:Department of Veterinary Science, South Dakota State University, Brookings, USA
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name:M. Lyte
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name:Mankato State University
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name:B. Arulanandam
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address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
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name:K. Nguyen
affiliation:
name:Mankato State University
address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
type:PostalAddress
type:Organization
name:C. Frank
affiliation:
name:Mankato State University
address:
name:Department of Biological Sciences, Mankato State University, Mankato, USA
type:PostalAddress
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name:A. Erickson
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name:South Dakota State University
address:
name:Department of Veterinary Science, South Dakota State University, Brookings, USA
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name:D. Francis
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address:
name:Department of Veterinary Science, South Dakota State University, Brookings, USA
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