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Title:
Human Tumor Xenograft Models in NCI Drug Development | SpringerLink
Description:
The preclinical discovery and development of anticancer drugs by the NCI consist of a series of test procedures, data review, and decision steps that have been summarized recently (1). Test procedures are designed to provide comparative quantitative data, which in...
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Keywords {🔍}

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Topics {✒️}

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Schema {🗺️}

ScholarlyArticle:
      headline:Human Tumor Xenograft Models in NCI Drug Development
      pageEnd:125
      pageStart:101
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4615-8152-9.jpg
      genre:
         Medicine
         Medicine (R0)
      isPartOf:
         name:Anticancer Drug Development Guide
         isbn:
            978-1-4615-8152-9
            978-1-4615-8154-3
         type:Book
      publisher:
         name:Humana Press
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Jacqueline Plowman
            affiliation:
            type:Person
            name:Donald J. Dykes
            affiliation:
            type:Person
            name:Melinda Hollingshead
            affiliation:
            type:Person
            name:Linda Simpson-Herren
            affiliation:
            type:Person
            name:Michael C. Alley
            affiliation:
            type:Person
      keywords:Hollow Fiber, Test Agent, Athymic Mouse, Human Tumor Xenograft, Human Tumor Xenograft Model
      description:The preclinical discovery and development of anticancer drugs by the NCI consist of a series of test procedures, data review, and decision steps that have been summarized recently (1). Test procedures are designed to provide comparative quantitative data, which in turn, permit selection of the best candidate agents from a given chemical or biological class. Periodic, comprehensive reviews by various NCI committees serve not only to identify and expedite the development of active lead compounds that may provide more efficacious treatments for human malignancy, but also to eliminate agents that are inactive and/or highly toxic from further consideration.
      datePublished:1997
      isAccessibleForFree:
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Book:
      name:Anticancer Drug Development Guide
      isbn:
         978-1-4615-8152-9
         978-1-4615-8154-3
Organization:
      name:Humana Press
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Jacqueline Plowman
      affiliation:
      name:Donald J. Dykes
      affiliation:
      name:Melinda Hollingshead
      affiliation:
      name:Linda Simpson-Herren
      affiliation:
      name:Michael C. Alley
      affiliation:
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      isAccessibleForFree:
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