We are analyzing https://link.springer.com/chapter/10.1007/978-1-4615-4295-7_6.

Title:
The Cleared Mammary Fat Pad and the Transplantation of Mammary Gland Morphological Structures and Cells | SpringerLink
Description:
The mammary fat pad, when cleared of glandular tissues in female mice 3–4 weeks old, provides an ideal site for the transplantation of normal, hyperplastic, or malignant lesions of the mammary gland into syngeneic hosts. The cleared fat pad retains the...
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28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

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Topics {✒️}

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Schema {🗺️}

ScholarlyArticle:
      headline:The Cleared Mammary Fat Pad and the Transplantation of Mammary Gland Morphological Structures and Cells
      pageEnd:74
      pageStart:67
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4615-4295-7.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Methods in Mammary Gland Biology and Breast Cancer Research
         isbn:
            978-1-4615-4295-7
            978-1-4613-6927-1
         type:Book
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Lawrence J. T. Young
            affiliation:
                  name:University of California-Davis
                  address:
                     name:Center for Comparative Medicine, University of California-Davis, Davis, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Mammary Gland, Mouse Mammary Gland, Serial Transplantation, Human Mammary Gland, Normal Mammary Tissue
      description:The mammary fat pad, when cleared of glandular tissues in female mice 3–4 weeks old, provides an ideal site for the transplantation of normal, hyperplastic, or malignant lesions of the mammary gland into syngeneic hosts. The cleared fat pad retains the microenvironment necessary for the normal morphological growth of transplanted mammary gland elements. The biological development of mammary gland structures can be evaluated and lesions can be tested for cancer risk. Serial transplantation into cleared fat pads can provide pools of the tissue of choice for biochemical, immunological, and molecular analysis, for tissue culture, and for the perpetuation of hyperplastic tissues for future use. With the advent of transgenic and knockout mice, the clearing technique has become a powerful biological system wherein the effect of genes and their interactions on mammary neoplasia can be determined. This chapter describes the clearing and transplantation technique for mammary tissues and cells.
      datePublished:2000
      isAccessibleForFree:
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Book:
      name:Methods in Mammary Gland Biology and Breast Cancer Research
      isbn:
         978-1-4615-4295-7
         978-1-4613-6927-1
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of California-Davis
      address:
         name:Center for Comparative Medicine, University of California-Davis, Davis, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Lawrence J. T. Young
      affiliation:
            name:University of California-Davis
            address:
               name:Center for Comparative Medicine, University of California-Davis, Davis, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Center for Comparative Medicine, University of California-Davis, Davis, USA
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