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Title:
Neuropeptide Gene Families in Caenorhabditis elegans | SpringerLink
Description:
Neuropeptides are short sequences of amino acids that function in all multicellular organisms to communicate information between cells. The first sequence of a neuropeptide was reported in 19701 and the number of identified neuropeptides...
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Keywords {🔍}

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Topics {✒️}

g-protein-coupled receptor fmrfamide-related peptide-encoding gene caenorhabditis elegans kex2/subtilisin versatile dot-elisa method peptidylglycine alpha-amidating monooxygenase nonconditional dauer-constitutive mutations protein-coupled receptor npr-1 ca2+-dependent activator protein protein-coupled fmrfamide receptor post-embryonic developmental variant month download article/chapter egg-laying defective mutants caenorhabditis elegans egg-laying neurons expressing npr-1/gpcr nematode fmrfamide-related peptide fmrfamide-related gene family fmrf amide-related peptides fmrfamide-related peptide activation kinesin-related gene unc-104 putative insulin receptor dense-core vesicle protein-coupled receptor springer science+business media large-scale rnai screen nematode fmrfamide-related peptides pkc-1 regulates secretion proprotein convertase family privacy choices/manage cookies ca2+-binding protein ca2+-dependent exocytosis flp15 peptide receptor doublestranded rna encoded protein-coupled receptors device instant download vesicle transmembrane protein facilitates acetylcholine release protein gene families insect fmrfamide receptor fmrfamide-related decapeptide fmrfamide-related heptapeptide chapter neuropeptide systems free-living nematode pigment dispersing factors soluble guanylyl cyclases marks nj motor nervous system tlr-independent control mass spectrometric map caenorhabditis elegans lacking respective gene families

Schema {🗺️}

ScholarlyArticle:
      headline:Neuropeptide Gene Families in Caenorhabditis elegans
      pageEnd:137
      pageStart:98
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4419-6902-6.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Neuropeptide Systems as Targets for Parasite and Pest Control
         isbn:
            978-1-4419-6902-6
            978-1-4419-6901-9
         type:Book
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
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      author:
            name:Chris Li
            affiliation:
                  name:City College of the City University of New York
                  address:
                     name:Chris Li-Department of Biology, City College of the City University of New York, New York
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Kyuhyung Kim
            affiliation:
                  name:Brandeis University
                  address:
                     name:Department of Biology, Brandeis University, Waltham, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Caenorhabditis Elegans, Nematode Caenorhabditis Elegans, Ventral Cord, Pharyngeal Neuron, Head Neuron
      description: Neuropeptides are short sequences of amino acids that function in all multicellular organisms to communicate information between cells. The first sequence of a neuropeptide was reported in 19701 and the number of identified neuropeptides remained relatively small until the 1990s when the DNA sequence of multiple genomes revealed treasure troves of information. By blasting away at the genome, gene families, the sizes of which were previously unknown, could now be determined. This information has led to an exponential increase in the number of putative neuropeptides and their respective gene families. The molecular biology age greatly benefited the neuropeptide field in the nematode Caenorhabditis elegans. Its genome was among the first to be sequenced2 and this allowed us the opportunity to screen the genome for neuropeptide genes. Initially, the screening was slow, as the Genefinder and BLAST programs had difficulty identifying small genes and peptides. However, as the bioinformatics programs improved, the extent of the neuropeptide gene families in C. elegans gradually emerged.
      datePublished:2010
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Book:
      name:Neuropeptide Systems as Targets for Parasite and Pest Control
      isbn:
         978-1-4419-6902-6
         978-1-4419-6901-9
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      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:City College of the City University of New York
      address:
         name:Chris Li-Department of Biology, City College of the City University of New York, New York
         type:PostalAddress
      name:Brandeis University
      address:
         name:Department of Biology, Brandeis University, Waltham, USA
         type:PostalAddress
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      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
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      affiliation:
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            address:
               name:Chris Li-Department of Biology, City College of the City University of New York, New York
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Kyuhyung Kim
      affiliation:
            name:Brandeis University
            address:
               name:Department of Biology, Brandeis University, Waltham, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Chris Li-Department of Biology, City College of the City University of New York, New York
      name:Department of Biology, Brandeis University, Waltham, USA
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