We are analyzing https://link.springer.com/chapter/10.1007/1-4020-3764-3_14.

Title:
Deregulation of the Centrosome Cycle and the Origin of Chromosomal Instability in Cancer | SpringerLink
Description:
No description found...
Website Age:
28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

google, scholar, cas, pubmed, article, cell, centrosome, biol, cancer, kinase, instability, protein, human, mitotic, nigg, cells, cycle, phosphorylation, sci, duplication, amplification, res, oncogene, required, mol, centrosomes, chromosome, chromosomal, chem, centrosomal, pololike, function, salisbury, plk, spindle, nat, fry, development, kinases, chapter, lingle, nek, breast, genomic, auroraa, centriole, overexpression, aneuploidy, sen, regulation,

Topics {✒️}

/stk15/btak overexpression correlates month download article/chapter induces mdm2-mediated destabilization high-affinity binding protein spindle pole/centrosome overproduction epidermal-targeted p53172h mutant g1/s-arrested cells active cyclin b1-cdk1 centrosomal coiled-coil protein microtubule-stabilizing protein tctp ring heterodimer brca1-bard1 cytometric s-phase determination coiled-coil proteins akap450 multiple coiled-coil domains microtubule-kinetochore attachment checkpoint nima-related protein kinases cyclin-dependent kinase control protein kinases cdk1-cyclin human anaphase-promoting complex type ii isozymes cell cycle-dependent expression cell cycle-dependent phosphorylation breast cancer-derived mutation cyclin-ubiquitin ligase activity mammalian gene related privacy choices/manage cookies bmc cell biol phosphopeptide specific antibodies nima-related kinase 2 e7 oncoproteins cooperate toyoshima-morimoto cyclin-dependent kinase 2 device instant download human mps1 kinase human papillomavirus oncoproteins basal body proteome nat rev cancer human protein kinase spindle assembly checkpoint nek2 protein kinase nuclear movement protein cell cycle checkpoint drosophila mitotic cells ubiquitin ligase inactivated gene expression patterns breast tumour development cancer metastasis rev human ninein protein p53 tumour suppression induce genetic instability

Questions {❓}

Centrosome aberrations: cause or consequence of cancer progression?
Chromosome instability in cancer: How, when, and why?

Schema {🗺️}

ScholarlyArticle:
      headline:Deregulation of the Centrosome Cycle and the Origin of Chromosomal Instability in Cancer
      pageEnd:421
      pageStart:393
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4020-3764-1.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Genome Instability in Cancer Development
         isbn:
            978-1-4020-3764-1
            978-1-4020-3763-4
         type:Book
      publisher:
         name:Springer Netherlands
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Wilma L. Lingle
            affiliation:
                  name:Mayo Clinic Cancer Center
                  address:
                     name:Mayo Clinic Cancer Center, Rochester, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kara Lukasiewicz
            affiliation:
                  name:Mayo Clinic Cancer Center
                  address:
                     name:Mayo Clinic Cancer Center, Rochester, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jeffrey L. Salisbury
            affiliation:
                  name:Mayo Clinic Cancer Center
                  address:
                     name:Mayo Clinic Cancer Center, Rochester, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Chromosomal Instability, Spindle Pole, Testicular Germ Cell Tumour, Mitotic Catastrophe, Centrosome Amplification
      description:
      datePublished:2005
      isAccessibleForFree:
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Book:
      name:Genome Instability in Cancer Development
      isbn:
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         978-1-4020-3763-4
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      name:Springer Netherlands
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         type:ImageObject
      name:Mayo Clinic Cancer Center
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      name:Kara Lukasiewicz
      affiliation:
            name:Mayo Clinic Cancer Center
            address:
               name:Mayo Clinic Cancer Center, Rochester, USA
               type:PostalAddress
            type:Organization
      name:Jeffrey L. Salisbury
      affiliation:
            name:Mayo Clinic Cancer Center
            address:
               name:Mayo Clinic Cancer Center, Rochester, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Mayo Clinic Cancer Center, Rochester, USA
      name:Mayo Clinic Cancer Center, Rochester, USA
      name:Mayo Clinic Cancer Center, Rochester, USA
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