We are analyzing https://link.springer.com/article/10.1385/ir:36:1:247.

Title:
Human tumor-derived vs dendritic cell-derived exosomes have distinct biologic roles and molecular profiles | Immunologic Research
Description:
Microvesicles (MV) or exosomes are produced and secreted by tumor and normal cells. The molecular profile and functions of tumor-derived vs dendritic cell (DC)-derived MV are distinct. The former express death ligands and mediate apoptosis of activated T cells. The latter promote CD4+T cell proliferation and may play a role in regulating T cell responses. Serving as intercellular communication networks, tumor-derived MV contribute to tumor escape, while DC-derived MV drive and regulate immune response.
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Keywords {🔍}

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Topics {✒️}

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Questions {❓}

Tumour-derived exosomes or microvesicles: another mechanism of tumour escape from the host immune system?

Schema {🗺️}

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         description:Microvesicles (MV) or exosomes are produced and secreted by tumor and normal cells. The molecular profile and functions of tumor-derived vs dendritic cell (DC)-derived MV are distinct. The former express death ligands and mediate apoptosis of activated T cells. The latter promote CD4+T cell proliferation and may play a role in regulating T cell responses. Serving as intercellular communication networks, tumor-derived MV contribute to tumor escape, while DC-derived MV drive and regulate immune response.
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