LINK . SPRINGER . COM {}

Matching Content Categories {📚}

• Science
• Health & Fitness
• Education

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 7,626,432 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure how the site profits.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

cancer, article, google, scholar, breast, heterogeneity, phd, cas, tumor, takabe, kawaguchi, cell, data, immune, survival, cells, kazuaki, department, analysis, oncology, facs, surgery, yan, intratumor, res, oncol, tumors, math, nat, buffalo, usa, university, patients, high, genome, clinical, comprehensive, roswell, park, privacy, cookies, content, research, mcdonald, tsutomu, young, genetic, mcgranahan, study, atlas,

Topics {✒️}

month download article/chapter investigator-initiated research grant kerry-ann mcdonald mutant-allele tumor heterogeneity intra-tumour heterogeneity real-world cohort utilizing t-cell exhaustion markers postoperative plasma sphingosine-1-phosphate inferring intra-tumor heterogeneity tamoxifen sensitivity-related microrna-342 triple-negative breast cancer intra-tumor genetic heterogeneity tumor-infiltrating immune cells aso author reflections cancer immunotherapy tumor microenvironment tumor heterogeneity correlates phd & eigo otsuji md cancer genome atlas single-cell genetic analysis privacy choices/manage cookies kazuaki takabe md full article pdf breast cancer patients anti-tumor cd8 complex cancer genomics human breast cancer invasive breast cancer pan-cancer analysis neck cancer patients ann surg oncol breast cancer res cytolytic activity score jessica young md article mcdonald tumour antigens pathology resource network breast cancer validated fatal breast cancer treatment resistance additional information publisher' triple-negative tumors shapes tumor heterogeneity cytolytic enzymes granzyme somatic dna alterations negative breast cancers research pathology services cancer immunol res natl cancer inst nat rev cancer

Questions {❓}

• Intra-tumour heterogeneity: A looking glass for cancer?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients
         description:Intratumor heterogeneity implies that subpopulations of cancer cells that differ in genetic, phenotypic, or behavioral characteristics coexist in a single tumor (Ma in Breast Cancer Res Treat 162(1):39–48, 2017; Martelotto in Breast Cancer Res 16(3):210, 2014). Tumor heterogeneity drives progression, metastasis and treatment resistance, but its relationship with tumor infiltrating immune cells is a matter of debate, where some argue that tumors with high heterogeneity may generate neoantigens that attract immune cells, and others claim that immune cells provide selection pressure that shapes tumor heterogeneity (McGranahan et al. in Science 351(6280):1463–1469, 2016; McGranahan and Swanton in Cell 168(4):613–628, 2017). We sought to study the association between tumor heterogeneity and immune cells in a real-world cohort utilizing The Cancer Genome Atlas. Mutant allele tumor heterogeneity (MATH) was calculated to estimate intratumoral heterogeneity, and immune cell compositions were estimated using CIBERSORT. Survival analyses were demonstrated using Kaplan–Meir curves. Tumors with high heterogeneity (high MATH) were associated with worse overall survival (p = 0.049), as well as estrogen receptor-positive (p = 0.011) and non-triple-negative tumors (p = 0.01). High MATH tumors were also associated with less infiltration of anti-tumor CD8 (p < 0.013) and CD4 T cells (p < 0.00024), more tumor-promoting regulatory T cells (p < 4e−04), lower expression of T-cell exhaustion markers, specifically PDL-1 (p = 0.0031), IDO2 (p = 0.34), ADORA2A (p = 0.018), VISTA (p = 0.00013), and CCR4 (p < 0.00001), lower expression of cytolytic enzymes granzyme A (p = 0.0056) and perforin 1 (p = 0.053), and low cytolytic activity score (p = 0.0028). High heterogeneity tumors are associated with less immune cell infiltration, less activation of the immune response, and worse survival in breast cancer. Our results support the notion that tumor heterogeneity is shaped by selection pressure of tumor-infiltrating immune cells.
         datePublished:2019-04-08T00:00:00Z
         dateModified:2019-04-08T00:00:00Z
         pageStart:2191
         pageEnd:2199
         sameAs:https://doi.org/10.1245/s10434-019-07338-3
         keywords:
            Surgical Oncology
            Oncology
            Surgery
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig4_HTML.png
         isPartOf:
            name:Annals of Surgical Oncology
            issn:
               1534-4681
               1068-9265
            volumeNumber:26
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer International Publishing
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Kerry-Ann McDonald
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tsutomu Kawaguchi
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
                     name:Kyoto Prefectural University of Medicine
                     address:
                        name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Qianya Qi
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Xuan Peng
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mariko Asaoka
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jessica Young
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mateusz Opyrchal
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Department of Medical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Li Yan
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Santosh Patnaik
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Thoracic Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Eigo Otsuji
               affiliation:
                     name:Kyoto Prefectural University of Medicine
                     address:
                        name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Kazuaki Takabe
               affiliation:
                     name:Roswell Park Comprehensive Cancer Center
                     address:
                        name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                        type:PostalAddress
                     type:Organization
                     name:The State University of New York
                     address:
                        name:Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, USA
                        type:PostalAddress
                     type:Organization
                     name:Tokyo Medical University
                     address:
                        name:Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
                     name:Yokohama City University
                     address:
                        name:Department of Surgery, Yokohama City University, Yokohama, Japan
                        type:PostalAddress
                     type:Organization
                     name:Niigata University Graduate School of Medical and Dental Sciences
                     address:
                        name:Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
                        type:PostalAddress
                     type:Organization
                     name:Fukushima Medical University
                     address:
                        name:Department of Breast Surgery and Oncology, Fukushima Medical University, Fukushima, Japan
                        type:PostalAddress
                     type:Organization
                     name:Roswell Park Cancer Institute
                     address:
                        name:Breast Oncology and Surgery, Roswell Park Cancer Institute, Buffalo, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients
      description:Intratumor heterogeneity implies that subpopulations of cancer cells that differ in genetic, phenotypic, or behavioral characteristics coexist in a single tumor (Ma in Breast Cancer Res Treat 162(1):39–48, 2017; Martelotto in Breast Cancer Res 16(3):210, 2014). Tumor heterogeneity drives progression, metastasis and treatment resistance, but its relationship with tumor infiltrating immune cells is a matter of debate, where some argue that tumors with high heterogeneity may generate neoantigens that attract immune cells, and others claim that immune cells provide selection pressure that shapes tumor heterogeneity (McGranahan et al. in Science 351(6280):1463–1469, 2016; McGranahan and Swanton in Cell 168(4):613–628, 2017). We sought to study the association between tumor heterogeneity and immune cells in a real-world cohort utilizing The Cancer Genome Atlas. Mutant allele tumor heterogeneity (MATH) was calculated to estimate intratumoral heterogeneity, and immune cell compositions were estimated using CIBERSORT. Survival analyses were demonstrated using Kaplan–Meir curves. Tumors with high heterogeneity (high MATH) were associated with worse overall survival (p = 0.049), as well as estrogen receptor-positive (p = 0.011) and non-triple-negative tumors (p = 0.01). High MATH tumors were also associated with less infiltration of anti-tumor CD8 (p < 0.013) and CD4 T cells (p < 0.00024), more tumor-promoting regulatory T cells (p < 4e−04), lower expression of T-cell exhaustion markers, specifically PDL-1 (p = 0.0031), IDO2 (p = 0.34), ADORA2A (p = 0.018), VISTA (p = 0.00013), and CCR4 (p < 0.00001), lower expression of cytolytic enzymes granzyme A (p = 0.0056) and perforin 1 (p = 0.053), and low cytolytic activity score (p = 0.0028). High heterogeneity tumors are associated with less immune cell infiltration, less activation of the immune response, and worse survival in breast cancer. Our results support the notion that tumor heterogeneity is shaped by selection pressure of tumor-infiltrating immune cells.
      datePublished:2019-04-08T00:00:00Z
      dateModified:2019-04-08T00:00:00Z
      pageStart:2191
      pageEnd:2199
      sameAs:https://doi.org/10.1245/s10434-019-07338-3
      keywords:
         Surgical Oncology
         Oncology
         Surgery
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_Fig4_HTML.png
      isPartOf:
         name:Annals of Surgical Oncology
         issn:
            1534-4681
            1068-9265
         volumeNumber:26
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer International Publishing
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Kerry-Ann McDonald
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tsutomu Kawaguchi
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
                  name:Kyoto Prefectural University of Medicine
                  address:
                     name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Qianya Qi
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Xuan Peng
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mariko Asaoka
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jessica Young
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mateusz Opyrchal
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Department of Medical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Li Yan
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Santosh Patnaik
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Thoracic Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Eigo Otsuji
            affiliation:
                  name:Kyoto Prefectural University of Medicine
                  address:
                     name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kazuaki Takabe
            affiliation:
                  name:Roswell Park Comprehensive Cancer Center
                  address:
                     name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
                     type:PostalAddress
                  type:Organization
                  name:The State University of New York
                  address:
                     name:Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, USA
                     type:PostalAddress
                  type:Organization
                  name:Tokyo Medical University
                  address:
                     name:Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
                  name:Yokohama City University
                  address:
                     name:Department of Surgery, Yokohama City University, Yokohama, Japan
                     type:PostalAddress
                  type:Organization
                  name:Niigata University Graduate School of Medical and Dental Sciences
                  address:
                     name:Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
                     type:PostalAddress
                  type:Organization
                  name:Fukushima Medical University
                  address:
                     name:Department of Breast Surgery and Oncology, Fukushima Medical University, Fukushima, Japan
                     type:PostalAddress
                  type:Organization
                  name:Roswell Park Cancer Institute
                  address:
                     name:Breast Oncology and Surgery, Roswell Park Cancer Institute, Buffalo, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Annals of Surgical Oncology
      issn:
         1534-4681
         1068-9265
      volumeNumber:26
Organization:
      name:Springer International Publishing
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Kyoto Prefectural University of Medicine
      address:
         name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Department of Medical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Thoracic Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:Kyoto Prefectural University of Medicine
      address:
         name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
         type:PostalAddress
      name:Roswell Park Comprehensive Cancer Center
      address:
         name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
         type:PostalAddress
      name:The State University of New York
      address:
         name:Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, USA
         type:PostalAddress
      name:Tokyo Medical University
      address:
         name:Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo, Japan
         type:PostalAddress
      name:Yokohama City University
      address:
         name:Department of Surgery, Yokohama City University, Yokohama, Japan
         type:PostalAddress
      name:Niigata University Graduate School of Medical and Dental Sciences
      address:
         name:Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
         type:PostalAddress
      name:Fukushima Medical University
      address:
         name:Department of Breast Surgery and Oncology, Fukushima Medical University, Fukushima, Japan
         type:PostalAddress
      name:Roswell Park Cancer Institute
      address:
         name:Breast Oncology and Surgery, Roswell Park Cancer Institute, Buffalo, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Kerry-Ann McDonald
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Tsutomu Kawaguchi
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
            name:Kyoto Prefectural University of Medicine
            address:
               name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
               type:PostalAddress
            type:Organization
      name:Qianya Qi
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Xuan Peng
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Mariko Asaoka
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Jessica Young
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Mateusz Opyrchal
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Department of Medical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Li Yan
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Santosh Patnaik
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Thoracic Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
      name:Eigo Otsuji
      affiliation:
            name:Kyoto Prefectural University of Medicine
            address:
               name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
               type:PostalAddress
            type:Organization
      name:Kazuaki Takabe
      affiliation:
            name:Roswell Park Comprehensive Cancer Center
            address:
               name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
               type:PostalAddress
            type:Organization
            name:The State University of New York
            address:
               name:Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, USA
               type:PostalAddress
            type:Organization
            name:Tokyo Medical University
            address:
               name:Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo, Japan
               type:PostalAddress
            type:Organization
            name:Yokohama City University
            address:
               name:Department of Surgery, Yokohama City University, Yokohama, Japan
               type:PostalAddress
            type:Organization
            name:Niigata University Graduate School of Medical and Dental Sciences
            address:
               name:Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
               type:PostalAddress
            type:Organization
            name:Fukushima Medical University
            address:
               name:Department of Breast Surgery and Oncology, Fukushima Medical University, Fukushima, Japan
               type:PostalAddress
            type:Organization
            name:Roswell Park Cancer Institute
            address:
               name:Breast Oncology and Surgery, Roswell Park Cancer Institute, Buffalo, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
      name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Department of Medical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Thoracic Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
      name:Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA
      name:Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, USA
      name:Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo, Japan
      name:Department of Surgery, Yokohama City University, Yokohama, Japan
      name:Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
      name:Department of Breast Surgery and Oncology, Fukushima Medical University, Fukushima, Japan
      name:Breast Oncology and Surgery, Roswell Park Cancer Institute, Buffalo, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(122)

• Revenue of https://www.springernature.com/gp/authors
• https://link.springernature.com/home/'s total income per month
• Discover the revenue of https://order.springer.com/public/cart
• What is the monthly revenue of https://mc.manuscriptcentral.com/aso?
• What is the earnings of https://www.springernature.com/gp/librarians/licensing/agc/journals?
• What's the income of http://scholar.google.com/scholar_lookup?&title=Clinical%20and%20molecular%20relevance%20of%20mutant-allele%20tumor%20heterogeneity%20in%20breast%20cancer&journal=Breast%20Cancer%20Res%20Treat.&doi=10.1007%2Fs10549-017-4113-z&volume=162&issue=1&pages=39-48&publication_year=2017&author=Ma%2CD&author=Jiang%2CYZ&author=Liu%2CXY&author=Liu%2CYR&author=Shao%2CZM?
• http://scholar.google.com/scholar_lookup?&title=Breast%20cancer%20intra-tumor%20heterogeneity&journal=Breast%20Cancer%20Res&doi=10.1186%2Fbcr3658&volume=16&issue=3&publication_year=2014&author=Martelotto%2CLG&author=Ng%2CCK&author=Piscuoglio%2CS&author=Weigelt%2CB&author=Reis-Filho%2CJS income
• Discover the revenue of https://doi.org/10.1126%2Fscience.aaf1490
• How much does http://scholar.google.com/scholar_lookup?&title=Clonal%20neoantigens%20elicit%20T%20cell%20immunoreactivity%20and%20sensitivity%20to%20immune%20checkpoint%20blockade&journal=Science.&doi=10.1126%2Fscience.aaf1490&volume=351&issue=6280&pages=1463-1469&publication_year=2016&author=McGranahan%2CN&author=Furness%2CAJ&author=Rosenthal%2CR gross monthly?
• How much revenue does https://doi.org/10.1016%2Fj.cell.2017.01.018 produce monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Clonal%20heterogeneity%20and%20tumor%20evolution%3A%20Past%2C%20present%2C%20and%20the%20future&journal=Cell.&doi=10.1016%2Fj.cell.2017.01.018&volume=168&issue=4&pages=613-628&publication_year=2017&author=McGranahan%2CN&author=Swanton%2CC pull in monthly?
• What are the earnings of https://doi.org/10.1038%2Fnrc3261?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Intra-tumour%20heterogeneity%3A%20A%20looking%20glass%20for%20cancer%3F&journal=Nat%20Rev%20Cancer.&doi=10.1038%2Fnrc3261&volume=12&issue=5&pages=323-334&publication_year=2012&author=Marusyk%2CA&author=Almendro%2CV&author=Polyak%2CK
• How much does https://doi.org/10.1038%2Fnm.3984 rake in every month?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Pan-cancer%20analysis%20of%20the%20extent%20and%20consequences%20of%20intratumor%20heterogeneity&journal=Nat%20Med.&doi=10.1038%2Fnm.3984&volume=22&issue=1&pages=105-113&publication_year=2016&author=Andor%2CN&author=Graham%2CTA&author=Jansen%2CM
• How much does https://doi.org/10.1016%2Fj.oraloncology.2012.09.007 pull in?
• Earnings of http://scholar.google.com/scholar_lookup?&title=MATH%2C%20a%20novel%20measure%20of%20intratumor%20genetic%20heterogeneity%2C%20is%20high%20in%20poor-outcome%20classes%20of%20head%20and%20neck%20squamous%20cell%20carcinoma&journal=Oral%20Oncol.&doi=10.1016%2Fj.oraloncology.2012.09.007&volume=49&issue=3&pages=211-215&publication_year=2013&author=Mroz%2CEA&author=Rocco%2CJW
• Learn about the earnings of https://doi.org/10.1016%2Fj.clcc.2016.11.004
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Mutant-allele%20tumor%20heterogeneity%20scores%20correlate%20with%20risk%20of%20metastases%20in%20colon%20cancer&journal=Clin%20Colorectal%20Cancer.&doi=10.1016%2Fj.clcc.2016.11.004&volume=16&issue=3&pages=e165-e170&publication_year=2017&author=Rajput%2CA&author=Bocklage%2CT&author=Greenbaum%2CA&author=Lee%2CJH&author=Ness%2CSA?
• What's the financial gain of https://doi.org/10.1371%2Fjournal.pmed.1001844?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Correction%3A%20Intra-tumor%20genetic%20heterogeneity%20and%20mortality%20in%20head%20and%20neck%20cancer%3A%20Analysis%20of%20data%20from%20the%20cancer%20genome%20atlas&journal=PLoS%20Med.&doi=10.1371%2Fjournal.pmed.1001844&volume=12&issue=6&publication_year=2015
• https://doi.org/10.1038%2Fnature12625's revenue stream
• How much profit does http://scholar.google.com/scholar_lookup?&title=The%20causes%20and%20consequences%20of%20genetic%20heterogeneity%20in%20cancer%20evolution&journal=Nature.&doi=10.1038%2Fnature12625&volume=501&issue=7467&pages=338-345&publication_year=2013&author=Burrell%2CRA&author=McGranahan%2CN&author=Bartek%2CJ&author=Swanton%2CC make?
• Explore the financials of https://doi.org/10.1038%2Fnature11412
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Comprehensive%20molecular%20portraits%20of%20human%20breast%20tumours&journal=Nature.&doi=10.1038%2Fnature11412&volume=490&issue=7418&pages=61-70&publication_year=2012&author=Network%2CCancer%20Genome%20Atlas?
• What are the earnings of https://doi.org/10.1158%2F2159-8290.CD-12-0095?
• What's http://scholar.google.com/scholar_lookup?&title=The%20cBio%20cancer%20genomics%20portal%3A%20an%20open%20platform%20for%20exploring%20multidimensional%20cancer%20genomics%20data&journal=Cancer%20Discov.&doi=10.1158%2F2159-8290.CD-12-0095&volume=2&issue=5&pages=401-404&publication_year=2012&author=Cerami%2CE&author=Gao%2CJ&author=Dogrusoz%2CU's gross income?
• What's https://doi.org/10.1155%2F2017%2F5984819's gross income?
• See how much http://scholar.google.com/scholar_lookup?&title=Paradoxical%20association%20of%20postoperative%20plasma%20sphingosine-1-phosphate%20with%20breast%20cancer%20aggressiveness%20and%20chemotherapy&journal=Mediators%20Inflamm.&doi=10.1155%2F2017%2F5984819&volume=2017&publication_year=2017&author=Ramanathan%2CR&author=Raza%2CA&author=Sturgill%2CJ makes per month
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Angiopoietin%20pathway%20gene%20expression%20associated%20with%20poor%20breast%20cancer%20survival&journal=Breast%20Cancer%20Res%20Treat.&doi=10.1007%2Fs10549-017-4102-2&volume=162&issue=1&pages=191-198&publication_year=2017&author=Ramanathan%2CR&author=Olex%2CAL&author=Dozmorov%2CM&author=Bear%2CHD&author=Fernandez%2CLJ&author=Takabe%2CK is on a monthly basis
• Get to know what's the income of https://doi.org/10.1245%2Fs10434-017-5984-2
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Clinical%20relevance%20of%20microRNA%20expressions%20in%20breast%20cancer%20validated%20using%20the%20cancer%20genome%20atlas%20%28TCGA%29&journal=Ann%20Surg%20Oncol.&doi=10.1245%2Fs10434-017-5984-2&volume=24&issue=10&pages=2943-2949&publication_year=2017&author=Kim%2CSY&author=Kawaguchi%2CT&author=Yan%2CL&author=Young%2CJ&author=Qi%2CQ&author=Takabe%2CK
• What's the financial outcome of https://doi.org/10.18632%2Foncotarget.24903?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Ceramide%20species%20are%20elevated%20in%20human%20breast%20cancer%20and%20are%20associated%20with%20less%20aggressiveness&journal=Oncotarget.&doi=10.18632%2Foncotarget.24903&volume=9&issue=28&pages=19874-19890&publication_year=2018&author=Moro%2CK&author=Kawaguchi%2CT&author=Tsuchida%2CJ
• Profit of https://doi.org/10.1038%2Fs41598-017-16112-y
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Overexpression%20of%20suppressive%20microRNAs%2C%20miR-30a%20and%20miR-200c%20are%20associated%20with%20improved%20survival%20of%20breast%20cancer%20patients&journal=Sci%20Rep.&doi=10.1038%2Fs41598-017-16112-y&volume=7&issue=1&publication_year=2017&author=Kawaguchi%2CT&author=Yan%2CL&author=Qi%2CQ is on a monthly basis
• How much does https://doi.org/10.18632%2Foncotarget.21577 pull in?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Tamoxifen%20sensitivity-related%20microRNA-342%20is%20a%20useful%20biomarker%20for%20breast%20cancer%20survival&journal=Oncotarget.&doi=10.18632%2Foncotarget.21577&volume=8&issue=59&pages=99978-99989&publication_year=2017&author=Young%2CJ&author=Kawaguchi%2CT&author=Yan%2CL&author=Qi%2CQ&author=Liu%2CS&author=Takabe%2CK is on a monthly basis
• How much does https://doi.org/10.1245%2Fs10434-018-6859-x pull in monthly?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Novel%20MicroRNA-based%20risk%20score%20identified%20by%20integrated%20analyses%20to%20predict%20metastasis%20and%20poor%20prognosis%20in%20breast%20cancer&journal=Ann%20Surg%20Oncol.&doi=10.1245%2Fs10434-018-6859-x&volume=25&issue=13&pages=4037-4046&publication_year=2018&author=Kawaguchi%2CT&author=Yan%2CL&author=Qi%2CQ?
• What's the income of https://doi.org/10.1245%2Fs10434-018-6957-9?
• What's http://scholar.google.com/scholar_lookup?&title=ASO%20author%20reflections%3A%20%E2%80%9CFrom%20computer%20to%20bedside%E2%80%9D%3A%20A%20new%20translational%20approach%20to%20immunogenomics&journal=Ann%20Surg%20Oncol.&doi=10.1245%2Fs10434-018-6957-9&volume=25&issue=Suppl%203&pages=846-847&publication_year=2018&author=Kawaguchi%2CT&author=Narayanan%2CS&author=Takabe%2CK's gross income?
• How much does http://scholar.google.com/scholar_lookup?&title=Mutant%20allele%20tumor%20heterogeneity%20%28MATH%29%20and%20head%20and%20neck%20squamous%20cell%20carcinoma&journal=Head%20Neck%20Pathol.&doi=10.1007%2Fs12105-015-0617-1&volume=9&issue=1&pages=1-5&publication_year=2015&author=Rocco%2CJW generate monthly?
• Learn how profitable https://doi.org/10.1371%2Fjournal.pone.0051862 is on a monthly basis
• http://scholar.google.com/scholar_lookup?&title=Cutoff%20finder%3A%20A%20comprehensive%20and%20straightforward%20web%20application%20enabling%20rapid%20biomarker%20cutoff%20optimization&journal=PLoS%20One.&doi=10.1371%2Fjournal.pone.0051862&volume=7&issue=12&publication_year=2012&author=Budczies%2CJ&author=Klauschen%2CF&author=Sinn%2CBV's revenue stream
• How much does https://doi.org/10.1371%2Fjournal.pone.0176231 rake in every month?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Determining%20the%20optimal%20number%20and%20location%20of%20cutoff%20points%20with%20application%20to%20data%20of%20cervical%20cancer&journal=PLoS%20One.&doi=10.1371%2Fjournal.pone.0176231&volume=12&issue=4&publication_year=2017&author=Chang%2CC&author=Hsieh%2CMK&author=Chang%2CWY&author=Chiang%2CAJ&author=Chen%2CJ generate?
• What's the total monthly financial gain of https://doi.org/10.1002%2F%28SICI%291097-0258%2820000115%2919%3A1%3C113%3A%3AAID-SIM245%3E3.0.CO%3B2-O?
• http://scholar.google.com/scholar_lookup?&title=Categorizing%20a%20prognostic%20variable%3A%20Review%20of%20methods%2C%20code%20for%20easy%20implementation%20and%20applications%20to%20decision-making%20about%20cancer%20treatments&journal=Stat%20Med.&doi=10.1002%2F%28SICI%291097-0258%2820000115%2919%3A1%3C113%3A%3AAID-SIM245%3E3.0.CO%3B2-O&volume=19&issue=1&pages=113-132&publication_year=2000&author=Mazumdar%2CM&author=Glassman%2CJR income
• How much income does https://doi.org/10.1016%2Fj.ctro.2017.01.001 have?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Plasma%20proteins%20as%20prognostic%20biomarkers%20in%20radiotherapy%20treated%20head%20and%20neck%20cancer%20patients&journal=Clin%20Transl%20Radiat%20Oncol.&doi=10.1016%2Fj.ctro.2017.01.001&volume=2&pages=46-52&publication_year=2017&author=Brondum%2CL&author=Eriksen%2CJG&author=Singers%20Sorensen%2CB
• Income figures for https://doi.org/10.3389%2Ffmed.2017.00227
• How much profit does http://scholar.google.com/scholar_lookup?&title=Tumor%20heterogeneity%20in%20breast%20cancer&journal=Front%20Med%20%28Lausanne%29.&doi=10.3389%2Ffmed.2017.00227&volume=4&publication_year=2017&author=Turashvili%2CG&author=Brogi%2CE make?
• What's the profit of https://doi.org/10.18632%2Foncotarget.7067?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Pan-cancer%20analysis%20of%20intratumor%20heterogeneity%20as%20a%20prognostic%20determinant%20of%20survival&journal=Oncotarget.&doi=10.18632%2Foncotarget.7067&volume=7&issue=9&pages=10051-10063&publication_year=2016&author=Morris%2CLG&author=Riaz%2CN&author=Desrichard%2CA?
• How much revenue does https://doi.org/10.1016%2Fj.semcdb.2016.08.025 generate?
• http://scholar.google.com/scholar_lookup?&title=Molecular%20heterogeneity%20in%20breast%20cancer%3A%20State%20of%20the%20science%20and%20implications%20for%20patient%20care&journal=Semin%20Cell%20Dev%20Biol.&doi=10.1016%2Fj.semcdb.2016.08.025&volume=64&pages=65-72&publication_year=2017&author=Ellsworth%2CRE&author=Blackburn%2CHL&author=Shriver%2CCD&author=Soon-Shiong%2CP&author=Ellsworth%2CDL's financial summary
• Learn how profitable https://doi.org/10.1371%2Fjournal.pone.0135007 is on a monthly basis
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Single-cell%20genetic%20analysis%20using%20automated%20microfluidics%20to%20resolve%20somatic%20mosaicism&journal=PLoS%20One.&doi=10.1371%2Fjournal.pone.0135007&volume=10&issue=8&publication_year=2015&author=Szulwach%2CKE&author=Chen%2CP&author=Wang%2CX
• How much money does https://doi.org/10.1093%2Fjnci%2Fdjx270 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Intratumor%20heterogeneity%20of%20the%20estrogen%20receptor%20and%20the%20long-term%20risk%20of%20fatal%20breast%20cancer&journal=J%20Natl%20Cancer%20Inst.&doi=10.1093%2Fjnci%2Fdjx270&volume=110&issue=7&pages=726-733&publication_year=2018&author=Lindstr%C3%B6m%2CLS&author=Yau%2CC&author=Czene%2CK pull in monthly?
• How much does https://doi.org/10.1038%2Fnmeth.2883 pull in monthly?
• How profitable is http://scholar.google.com/scholar_lookup?&title=PyClone%3A%20Statistical%20inference%20of%20clonal%20population%20structure%20in%20cancer&journal=Nat%20Methods.&doi=10.1038%2Fnmeth.2883&volume=11&issue=4&pages=396-398&publication_year=2014&author=Roth%2CA&author=Khattra%2CJ&author=Yap%2CD?
• How much profit does http://scholar.google.com/scholar_lookup?&title=THetA%3A%20Inferring%20intra-tumor%20heterogeneity%20from%20high-throughput%20DNA%20sequencing%20data&journal=Genome%20Biol.&doi=10.1186%2Fgb-2013-14-7-r80&volume=14&issue=7&publication_year=2013&author=Oesper%2CL&author=Mahmoody%2CA&author=Raphael%2CBJ generate?
• Revenue of https://doi.org/10.1038%2Fnbt.2203
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Absolute%20quantification%20of%20somatic%20DNA%20alterations%20in%20human%20cancer&journal=Nat%20Biotechnol.&doi=10.1038%2Fnbt.2203&volume=30&issue=5&pages=413-421&publication_year=2012&author=Carter%2CSL&author=Cibulskis%2CK&author=Helman%2CE?
• How much does https://doi.org/10.1172%2FJCI67428 earn?
• http://scholar.google.com/scholar_lookup?&title=CD4%28%2B%29%20follicular%20helper%20T%20cell%20infiltration%20predicts%20breast%20cancer%20survival&journal=J%20Clin%20Invest.&doi=10.1172%2FJCI67428&volume=123&issue=7&pages=2873-2892&publication_year=2013&author=Gu-Trantien%2CC&author=Loi%2CS&author=Garaud%2CS's financial summary
• How much does http://scholar.google.com/scholar_lookup?&title=Stromal%20mast%20cells%20in%20invasive%20breast%20cancer%20are%20a%20marker%20of%20favourable%20prognosis%3A%20A%20study%20of%204%2C444%20cases&journal=Breast%20Cancer%20Res%20Treat.&doi=10.1007%2Fs10549-007-9546-3&volume=107&issue=2&pages=249-257&publication_year=2008&author=Rajput%2CAB&author=Turbin%2CDA&author=Cheang%2CMC earn?
• See how much https://doi.org/10.1038%2Fnrclinonc.2016.66 makes per month
• What's the income of http://scholar.google.com/scholar_lookup?&title=Triple-negative%20breast%20cancer%3A%20Challenges%20and%20opportunities%20of%20a%20heterogeneous%20disease&journal=Nat%20Rev%20Clin%20Oncol.&doi=10.1038%2Fnrclinonc.2016.66&volume=13&issue=11&pages=674-690&publication_year=2016&author=Bianchini%2CG&author=Balko%2CJM&author=Mayer%2CIA&author=Sanders%2CME&author=Gianni%2CL?
• What's the profit of https://doi.org/10.1016%2Fj.it.2012.10.001?
• Revenue of http://scholar.google.com/scholar_lookup?&title=Indoleamine%202%2C3%20dioxygenase%20and%20metabolic%20control%20of%20immune%20responses&journal=Trends%20Immunol.&doi=10.1016%2Fj.it.2012.10.001&volume=34&issue=3&pages=137-143&publication_year=2013&author=Munn%2CDH&author=Mellor%2CAL
• How much does https://doi.org/10.1158%2F0008-5472.CAN-13-3581 bring in each month?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Adenosine%20A2A%20receptors%20intrinsically%20regulate%20CD8%2B%20T%20cells%20in%20the%20tumor%20microenvironment&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-13-3581&volume=74&issue=24&pages=7239-7249&publication_year=2014&author=Cekic%2CC&author=Linden%2CJ make?
• How much revenue does https://doi.org/10.1158%2F2326-6066.CIR-14-0072 bring in?
• Earnings of http://scholar.google.com/scholar_lookup?&title=VISTA%20is%20a%20novel%20broad-spectrum%20negative%20checkpoint%20regulator%20for%20cancer%20immunotherapy&journal=Cancer%20Immunol%20Res.&doi=10.1158%2F2326-6066.CIR-14-0072&volume=2&issue=6&pages=510-517&publication_year=2014&author=Lines%2CJL&author=Sempere%2CLF&author=Broughton%2CT&author=Wang%2CL&author=Noelle%2CR
• How much revenue does https://doi.org/10.1038%2Fnri911 bring in?
• How much does http://scholar.google.com/scholar_lookup?&title=Functional%20significance%20of%20the%20perforin%2Fgranzyme%20cell%20death%20pathway&journal=Nat%20Rev%20Immunol.&doi=10.1038%2Fnri911&volume=2&issue=10&pages=735-747&publication_year=2002&author=Trapani%2CJA&author=Smyth%2CMJ net monthly?
• What's the financial gain of https://citation-needed.springer.com/v2/references/10.1245/s10434-019-07338-3?format=refman&flavour=references?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kerry-Ann%20McDonald's total income per month
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kerry-Ann%20McDonald%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
• What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Tsutomu%20Kawaguchi?
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tsutomu%20Kawaguchi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qianya%20Qi make?
• What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qianya%20Qi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xuan%20Peng rake in every month?
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xuan%20Peng%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mariko%20Asaoka produce monthly?
• What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mariko%20Asaoka%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jessica%20Young
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jessica%20Young%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• Learn about the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mateusz%20Opyrchal
• What's the monthly money flow for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mateusz%20Opyrchal%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Li%20Yan?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Li%20Yan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Santosh%20Patnaik
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Santosh%20Patnaik%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eigo%20Otsuji's gross income?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eigo%20Otsuji%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kazuaki%20Takabe's financial summary
• Profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kazuaki%20Takabe%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://static-content.springer.com/esm/art%3A10.1245%2Fs10434-019-07338-3/MediaObjects/10434_2019_7338_MOESM1_ESM.tif pull in monthly?
• How much profit does https://s100.copyright.com/AppDispatchServlet?title=Tumor%20Heterogeneity%20Correlates%20with%20Less%20Immune%20Response%20and%20Worse%20Survival%20in%20Breast%20Cancer%20Patients&author=Kerry-Ann%20McDonald%20MD%20et%20al&contentID=10.1245%2Fs10434-019-07338-3©right=Society%20of%20Surgical%20Oncology&publication=1068-9265&publicationDate=2019-04-08&publisherName=SpringerNature&orderBeanReset=true make?
• How much does https://crossmark.crossref.org/dialog/?doi=10.1245/s10434-019-07338-3 pull in?
• How much income is https://citation-needed.springer.com/v2/references/10.1245/s10434-019-07338-3?format=refman&flavour=citation earning monthly?
• How much profit does https://authorservices.springernature.com/go/sn/?utm_source=SNLinkfooter&utm_medium=Web&utm_campaign=SNReferral generate?
• See how much https://www.springernature.com/gp/open-research/about/the-fundamentals-of-open-access-and-open-research makes per month
• What's the financial gain of https://www.springernature.com/gp/products?
• What's the profit of https://www.springernature.com/gp/librarians?
• See how much https://www.springernature.com/gp/societies makes per month
• Learn how profitable https://www.springernature.com/gp/partners is on a monthly basis
• What's the total monthly financial gain of https://www.springer.com/?
• How much does https://www.nature.com/ pull in?
• Financial intake of https://www.biomedcentral.com/
• What is the earnings of https://www.palgrave.com/?
• How profitable is https://www.apress.com/?
• What are the earnings of https://www.springernature.com/gp/legal/ccpa?
• https://www.springernature.com/gp/info/accessibility's financial summary
• What's the monthly income of https://support.springernature.com/en/support/home?
• What's the income of https://support.springernature.com/en/support/solutions/articles/6000255911-subscription-cancellations?
• How much does https://www.springernature.com/ pull in monthly?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Clipboard.js
• Prism.js

CDN Services {📦}

• Crossref