We are analyzing https://link.springer.com/article/10.1245/s10434-015-4829-0.

Title:
Impact of Consensus Guidelines by the Society of Surgical Oncology and the American Society for Radiation Oncology on Margins for Breast-Conserving Surgery in Stages 1 and 2 Invasive Breast Cancer | Annals of Surgical Oncology
Description:
This study aimed to evaluate the impact that the release of consensus guidelines for margins in breast-conserving surgery (BCS) had on re-excision rates. A retrospective review examined a prospectively maintained database of patients who had operable invasive breast cancer treated with BCS at the authors’ institution. The patients were divided into two groups: (1) those with a diagnosis determined from 1 July 2011 to 31 July 2013 (before release of the guidelines) and (2) those with a diagnosis determined from 1 February 2014 to 31 July 2014 (after release of the guidelines). The groups were evaluated with respect to patient and tumor characteristics, re-excision rates, and reasons for re-excision. A total of 846 cases of BCS were managed: 597 in group 1 and 249 in group 2. Re-excision rates were significantly reduced after release of the consensus guidelines (p = 0.03). Re-excisions were performed for 115 (19 %) of 597 patients in group 1 and 32 (13 %) of 249 patients in group 2. After release of the guidelines, re-excisions were performed for positive margins, as defined by the consensus statement, in 25 (78 %) of 32 cases. The two groups did not differ significantly in terms of age, tumor size, grade, nodal status, estrogen receptor status, progesterone receptor status, or human epidermal growth factor receptor 2 status. Group 1 had more tumors of mixed ductal and lobular histology than group 2, and group 2 had more lobular tumors than group 1 (p = 0.02). The consensus guidelines on margins for BCS were applied for 78 % of the patients who underwent re-excision and resulted in a significant reduction in re-excision rates.
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Keywords {🔍}

pubmed, article, breast, google, scholar, cancer, invasive, breastconserving, surgery, oncol, margins, surg, margin, surgical, reexcision, oncology, ann, cas, consensus, ductal, lumpectomy, carcinoma, society, guidelines, group, status, lobular, central, rates, residual, radiation, patients, trial, therapy, assessment, impact, tumor, irradiation, women, local, privacy, cookies, content, data, stages, giuliano, release, receptor, center, excision,

Topics {✒️}

estrogen receptor status progesterone receptor status month download article/chapter cedars-sinai medical center sso-astro consensus guideline sso-astro consensus guidelines surgical margin status initial margin status surgical oncology–american society tumor-related factors influence full article pdf invasive ductal + invasive lobular early breast cancer breast cancer treated consensus statement privacy choices/manage cookies european cancer center surgical oncology aims randomised trial comparing breast-conserving surgery related subjects frozen-section margin randomised controlled trial invasive breast cancer breast conservation surgery intraductal breast cancer breast cancer tumorectomy breast-conserving therapy natl cancer inst article annals breast surgeons mastery invasive lobular carcinomas invasive ductal carcinomas european economic area scope submit manuscript aiello bowles ej touch preparation cytology schmidt-ullrich rk long term-outcome intraductal breast carcinoma intraoperative specimen inking intraoperative imprint cytology intraoperative ultrasound guidance women undergoing lumpectomy conditions privacy policy 1245/s10434-015-4666-1 invasive lobular carcinoma ann surg oncol check access instant access

Questions {❓}

Can intraductal breast carcinoma be excised completely by local excision?
Positive margins following breast cancer tumorectomy: can we predict the occurrence of residual disease?
What is an adequate margin for breast-conserving surgery?

Schema {🗺️}

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         description:This study aimed to evaluate the impact that the release of consensus guidelines for margins in breast-conserving surgery (BCS) had on re-excision rates. A retrospective review examined a prospectively maintained database of patients who had operable invasive breast cancer treated with BCS at the authors’ institution. The patients were divided into two groups: (1) those with a diagnosis determined from 1 July 2011 to 31 July 2013 (before release of the guidelines) and (2) those with a diagnosis determined from 1 February 2014 to 31 July 2014 (after release of the guidelines). The groups were evaluated with respect to patient and tumor characteristics, re-excision rates, and reasons for re-excision. A total of 846 cases of BCS were managed: 597 in group 1 and 249 in group 2. Re-excision rates were significantly reduced after release of the consensus guidelines (p = 0.03). Re-excisions were performed for 115 (19 %) of 597 patients in group 1 and 32 (13 %) of 249 patients in group 2. After release of the guidelines, re-excisions were performed for positive margins, as defined by the consensus statement, in 25 (78 %) of 32 cases. The two groups did not differ significantly in terms of age, tumor size, grade, nodal status, estrogen receptor status, progesterone receptor status, or human epidermal growth factor receptor 2 status. Group 1 had more tumors of mixed ductal and lobular histology than group 2, and group 2 had more lobular tumors than group 1 (p = 0.02). The consensus guidelines on margins for BCS were applied for 78 % of the patients who underwent re-excision and resulted in a significant reduction in re-excision rates.
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