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Diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma | Acta Neuropathologica Communications
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Keywords {š}
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Topics {āļø}
prc2-mediated repressive h3k27me2/me3 array-based methylation profiling dna methylation-based classification article download pdf scale barsā=ā40āμm integrative high-throughput sequencing high-grade cellular tumor full size image michigan peds-mioncoseq study t-sne dimensionality reduction densely cellular tumor mi-oncoseq integrative sequencing childhood posterior fossa h3k27m pediatric glioma rna-seq showed overexpression ependymomas termed pf-group hubner jm pediatric brain tumors consensus clustering analysis transcriptome-based techniques carl koschmann privacy choices/manage cookies pfas show overexpression posterior fossa group chromatin remodelling genes case showing clustering global h3k27me3 reduction prc2 methyltransferase activity pajtler kw medical center dr pediatric hematology/oncology repressive h3k27 trimethylation brain tumor metabolism pediatric brainstem tumors ezh inhibitory protein log-transformed fragments search search integrative clinical genomics provided clinical care infiltrative mass centered creative commons licence sriram venneti targeted epigenetic therapies tumors arising solely exam revealed evidence immunophenotypic findings suggested h3k27m mutant protein article pratt full access relevant alterations detected
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