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Title:
Controlling cell division in yeast and animals: does size matter? | Journal of Biology
Description:
In yeast, cell-size checkpoints coordinate cellular growth with cell-cycle progression. Now, evidence has been provided that such checkpoints probably do not exist in mammalian cells. These findings highlight an important difference between how yeast and animal cells proliferate in response to extracellular cues.
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Keywords {π}
cell, growth, size, cells, pubmed, article, google, scholar, cas, yeast, division, control, cellcycle, rates, cellsize, factors, checkpoints, extracellular, cycle, proliferation, conlon, controls, raff, animal, studies, nutrient, development, signals, signaling, drosophila, wing, edgar, progression, mammalian, findings, controlled, ensure, levels, cyclin, biol, nature, animals, patterning, act, hedgehog, regulators, pathways, privacy, cookies, content,
Topics {βοΈ}
wing imaginal disc pattern-signaling proteins decapentaplegic strict cell-size checkpoints increase cell-cycle progression ras signalling linked specific cell-size controls strict cell-size controls developing drosophila wing ribosome biogenesis [21] cell-size checkpoints operate cell-size checkpoints function nutrient-dependent signaling networks cell-cycle regulators cyclin glial-growth factor cell-cycle research cell-cycle mechanisms show cell-size control mechanisms privacy choices/manage cookies cultured schwann cells cell dna replication key regulatory genes sonic hedgehog promotes signals mediate cell cell-size checkpoints johnston la cell-cycle regulators cell-cycle progression cell cycle progression drosophila cdc2 kinase drosophila wing cell-cycle controls controlling cell division cell-cycle machinery nutrient-dependent controls mammalian neuronal precursors cell-size controls cell-fate specification cell-autonomous manner [12 exp cell res cell size appears cell size imposed reduce cell size determine cell size cell size resulted checking cell size schwann cells growth factor related subjects begin identifying links long twentieth century
Questions {β}
- But how are cell growth and cell size controlled?
- Controlling cell division in yeast and animals: does size matter?
- Controlling cell division in yeast and animals: does size matter?
- Do such cell-size checkpoints also exist in animal cells?
- How do fission yeast cells grow and connect growth to the mitotic cycle?
- One obvious question that stems from the findings of Conlon and Raff [6] is that if there are some extracellular factors that are pro-growth and some that are pro-cell division, how do they exert their effects?
- These observations have led to a fundamental question in cell biology: do cells monitor their size?
- Who needs size control?
Schema {πΊοΈ}
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headline:Controlling cell division in yeast and animals: does size matter?
description:In yeast, cell-size checkpoints coordinate cellular growth with cell-cycle progression. Now, evidence has been provided that such checkpoints probably do not exist in mammalian cells. These findings highlight an important difference between how yeast and animal cells proliferate in response to extracellular cues.
datePublished:2003-04-24T00:00:00Z
dateModified:2003-04-24T00:00:00Z
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headline:Controlling cell division in yeast and animals: does size matter?
description:In yeast, cell-size checkpoints coordinate cellular growth with cell-cycle progression. Now, evidence has been provided that such checkpoints probably do not exist in mammalian cells. These findings highlight an important difference between how yeast and animal cells proliferate in response to extracellular cues.
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Wing Imaginal Disc
Extracellular Factor
Drosophila Wing
Culture Schwann Cell
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