
LINK . SPRINGER . COM {
}
Title:
Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro | Archives of Pharmacal Research
Description:
Flavonoids exist extensively in the human diet, and a variety of health effects have been ascribed to them. The cytotoxic effects of 23 flavonoids on breast cancer cells (MDA-MB-231 and MCF-7), colorectal carcinoma cells (LoVo and DLD-1) and prostatic cancer cells (PC3) were investigated. By comparing the cytotoxicity (EC50) of selected molecules that differ in only one structure element, we identified several structural properties associated with enhanced cytotoxicity, including the presence of the 2,3-double bond, appropriate hydroxyl numbers, 3-OH, 6-OH and ortho-hydroxylation in ring B. Flavonoids with a 5-OH exhibited lower cytotoxicity than their non-hydroxylated counterparts. Results indicated that 3,6-dihydroxylflavone showed the most potent cytotoxic effect on these cancer cells. The appearance of apoptotic cells with DAPI staining was observed in cancer cells under 3,6-dihydroxylflavone treatment, and the apoptosis analysis by flow cytometry also showed that 3,6-dihydroxylflavone induced apoptotic cell death in these cancer cells. These results revealed the structurally related toxicity of flavonoids on human cancer cells, and indicates that 3,6-dihydroxylflavone is an active compound worthy of development for cancer chemotherapy.
Website Age:
28 years and 1 months (reg. 1997-05-29).
Matching Content Categories {π}
- Science
- Health & Fitness
- Education
Content Management System {π}
What CMS is link.springer.com built with?
Custom-built
No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of link.springer.com audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 7,626,432 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Link.springer.com Make Money? {πΈ}
We're unsure how the site profits.
While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com has a secret sauce for making money, but we can't detect it yet.
Keywords {π}
article, cancer, google, scholar, pubmed, cells, cas, flavonoids, cell, human, apoptosis, res, research, related, access, privacy, cookies, content, cytotoxic, effects, cytotoxicity, dihydroxylflavone, activity, inhibition, dietary, arch, pharm, kim, publish, search, structurally, vitro, ling, yong, induction, chen, prostate, data, information, log, journal, drug, april, chang, mantian, wenhua, health, breast, mcf, apoptotic,
Topics {βοΈ}
month download article/chapter cell cycle arrest potent cytotoxic effect modulating bcl-2-related proteins nonsteroidal flavone-methanesulfonate derivatives mcf-7 cell line 6-dihydroxylflavone pro-apoptosis access myeloma cell lines pharmacal research aims breast cancer cells cancer cell apoptosis structurally related toxicity full article pdf anti-inflammatory activity human cancer cells structure element privacy choices/manage cookies promising chemotherapeutic candidates human leukemia cells age-related variations apoptosis inducing activity related subjects mcf7 ras cells dietary compound luteolin prostatic cancer cells cytotoxic effects colorectal carcinoma cells european economic area active compound worthy monobenzyltin complex c1 van-der-vijgh acute lymphocytic leukemia rapid colorimetric assay article archives article chang prostate cancer risk mda-mb-231 cells conditions privacy policy military medical university apoptotic activity accepting optional cookies p21 gene expression exhibited lower cytotoxicity main content log cancer cells article log journal finder publish check access author correspondence instant access
Questions {β}
- , Dietary polyphenolic phytochemicals-promising cancer chemopreventive agents in humans?
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro
description:Flavonoids exist extensively in the human diet, and a variety of health effects have been ascribed to them. The cytotoxic effects of 23 flavonoids on breast cancer cells (MDA-MB-231 and MCF-7), colorectal carcinoma cells (LoVo and DLD-1) and prostatic cancer cells (PC3) were investigated. By comparing the cytotoxicity (EC50) of selected molecules that differ in only one structure element, we identified several structural properties associated with enhanced cytotoxicity, including the presence of the 2,3-double bond, appropriate hydroxyl numbers, 3-OH, 6-OH and ortho-hydroxylation in ring B. Flavonoids with a 5-OH exhibited lower cytotoxicity than their non-hydroxylated counterparts. Results indicated that 3,6-dihydroxylflavone showed the most potent cytotoxic effect on these cancer cells. The appearance of apoptotic cells with DAPI staining was observed in cancer cells under 3,6-dihydroxylflavone treatment, and the apoptosis analysis by flow cytometry also showed that 3,6-dihydroxylflavone induced apoptotic cell death in these cancer cells. These results revealed the structurally related toxicity of flavonoids on human cancer cells, and indicates that 3,6-dihydroxylflavone is an active compound worthy of development for cancer chemotherapy.
datePublished:2009-04-30T00:00:00Z
dateModified:2009-04-30T00:00:00Z
pageStart:1137
pageEnd:1144
sameAs:https://doi.org/10.1007/s12272-001-1280-8
keywords:
Flavonoids
Cytotoxic effect
Cancer cells
Structure-activity relationship
3,6-Dihydroxylflavone
Pro-apoptosis
Pharmacy
Pharmacology/Toxicology
image:
isPartOf:
name:Archives of Pharmacal Research
issn:
1976-3786
0253-6269
volumeNumber:31
type:
Periodical
PublicationVolume
publisher:
name:Pharmaceutical Society of Korea
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Hui Chang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Mantian Mi
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Wenhua Ling
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Sun Yet-sen University
address:
name:Department of Nutrition, Public Health School, Sun Yet-sen University, Guangzhou, China
type:PostalAddress
type:Organization
type:Person
name:Jundong Zhu
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Qianyong Zhang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Na Wei
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Yong Zhou
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Yong Tang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Jialin Yuan
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro
description:Flavonoids exist extensively in the human diet, and a variety of health effects have been ascribed to them. The cytotoxic effects of 23 flavonoids on breast cancer cells (MDA-MB-231 and MCF-7), colorectal carcinoma cells (LoVo and DLD-1) and prostatic cancer cells (PC3) were investigated. By comparing the cytotoxicity (EC50) of selected molecules that differ in only one structure element, we identified several structural properties associated with enhanced cytotoxicity, including the presence of the 2,3-double bond, appropriate hydroxyl numbers, 3-OH, 6-OH and ortho-hydroxylation in ring B. Flavonoids with a 5-OH exhibited lower cytotoxicity than their non-hydroxylated counterparts. Results indicated that 3,6-dihydroxylflavone showed the most potent cytotoxic effect on these cancer cells. The appearance of apoptotic cells with DAPI staining was observed in cancer cells under 3,6-dihydroxylflavone treatment, and the apoptosis analysis by flow cytometry also showed that 3,6-dihydroxylflavone induced apoptotic cell death in these cancer cells. These results revealed the structurally related toxicity of flavonoids on human cancer cells, and indicates that 3,6-dihydroxylflavone is an active compound worthy of development for cancer chemotherapy.
datePublished:2009-04-30T00:00:00Z
dateModified:2009-04-30T00:00:00Z
pageStart:1137
pageEnd:1144
sameAs:https://doi.org/10.1007/s12272-001-1280-8
keywords:
Flavonoids
Cytotoxic effect
Cancer cells
Structure-activity relationship
3,6-Dihydroxylflavone
Pro-apoptosis
Pharmacy
Pharmacology/Toxicology
image:
isPartOf:
name:Archives of Pharmacal Research
issn:
1976-3786
0253-6269
volumeNumber:31
type:
Periodical
PublicationVolume
publisher:
name:Pharmaceutical Society of Korea
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Hui Chang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Mantian Mi
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Wenhua Ling
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Sun Yet-sen University
address:
name:Department of Nutrition, Public Health School, Sun Yet-sen University, Guangzhou, China
type:PostalAddress
type:Organization
type:Person
name:Jundong Zhu
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Qianyong Zhang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Na Wei
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Yong Zhou
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Yong Tang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
name:Jialin Yuan
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Archives of Pharmacal Research
issn:
1976-3786
0253-6269
volumeNumber:31
Organization:
name:Pharmaceutical Society of Korea
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:Sun Yet-sen University
address:
name:Department of Nutrition, Public Health School, Sun Yet-sen University, Guangzhou, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Hui Chang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Mantian Mi
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
email:[email protected]
name:Wenhua Ling
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Sun Yet-sen University
address:
name:Department of Nutrition, Public Health School, Sun Yet-sen University, Guangzhou, China
type:PostalAddress
type:Organization
name:Jundong Zhu
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Qianyong Zhang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Na Wei
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Yong Zhou
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Yong Tang
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
name:Jialin Yuan
affiliation:
name:The Third Military Medical University
address:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
type:PostalAddress
type:Organization
PostalAddress:
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition, Public Health School, Sun Yet-sen University, Guangzhou, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
name:Department of Nutrition and Food Hygiene, School of Preventive Medicine, The Third Military Medical University, Chongqing, China
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {π}(106)
- https://www.springernature.com/gp/authors's total income per month
- What is the earnings of https://link.springernature.com/home/?
- https://order.springer.com/public/cart's total income per month
- https://www.editorialmanager.com/arpr/ income
- Profit of https://www.springernature.com/gp/librarians/licensing/agc/journals
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7585564 net monthly?
- How much income does http://scholar.google.com/scholar_lookup?&title=Sodium%20phenylacetate%20induces%20growth%20inhibition%20and%20Bcl-2%20down-regulation%20and%20apoptosis%20in%20MCF7%20ras%20cells%20in%20vitro%20and%20in%20nude%20mice&journal=Cancer.%20Res.&volume=55&pages=5156-5160&publication_year=1995&author=Adam%2CM.&author=Crepin%2CC.&author=Savin%2CC.&author=Israel%2CL. have?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17652822 bring in?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Protection%20by%20flavonoids%20against%20anthracycline%20cardiotoxicity%3A%20from%20chemistry%20to%20clinical%20trials&journal=Cardiovasc.%20Toxicol.&doi=10.1007%2Fs12012-007-0018-0&volume=7&pages=154-159&publication_year=2007&author=Bast%2CA.&author=Haenen%2CG.%20R.&author=Bruynzeel%2CA.%20M.&author=Van-der-Vijgh%2CW.%20J. each month?
- How much does https://doi.org/10.1089%2Facm.2006.12.133 generate monthly?
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16566672 making per month?
- Revenue of http://scholar.google.com/scholar_lookup?&title=The%20chemical%20and%20biologic%20profile%20of%20a%20red%20clover%20%28Trifolium%20pratense%20L.%29%20phase%20II%20clinical%20extract&journal=J.%20Altern.%20Complement.%20Med.&doi=10.1089%2Facm.2006.12.133&volume=12&pages=133-139&publication_year=2006&author=Booth%2CN.%20L.&author=Overk%2CC.%20R.&author=Yao%2CP.&author=Burdette%2CJ.%20E.&author=Nikolic%2CD.&author=Chen%2CS.%20N.
- How much does https://doi.org/10.1207%2Fs15327914nc5602_1 pull in monthly?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17474856 generate?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Flavonoids%20and%20prostate%20cancer%20risk%3A%20a%20study%20in%20Italy&journal=Nutr.%20Cancer.&doi=10.1207%2Fs15327914nc5602_1&volume=56&pages=123-127&publication_year=2006&author=Bosetti%2CC.&author=Bravi%2CF.&author=Talamini%2CR.&author=Parpinel%2CM.&author=Gnagnarella%2CP.&author=Negri%2CE.&author=Montella%2CM.&author=Lagiou%2CP.&author=Franceschi%2CS.&author=La-Vecchia%2CC.?
- How profitable is https://doi.org/10.1074%2Fjbc.M408177200?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15533929 gross monthly?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Induction%20of%20cancer%20cell%20apoptosis%20by%20flavonoids%20is%20associated%20with%20their%20ability%20to%20inhibit%20fatty%20acid%20synthase%20activity&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M408177200&volume=280&pages=5636-5645&publication_year=2005&author=Brusselmans%2CK.&author=Vrolix%2CR.&author=Verhoeven%2CG.&author=Swinnen%2CJ.%20V. generate?
- What's the financial outcome of https://doi.org/10.1016%2Fj.bcp.2005.02.022?
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15857606 making per month?
- How much income is http://scholar.google.com/scholar_lookup?&title=Dietary%20flavonoids%20as%20proteasome%20inhibitors%20and%20apoptosis%20inducers%20in%20human%20leukemia%20cells&journal=Biochem.%20Pharmacol.&doi=10.1016%2Fj.bcp.2005.02.022&volume=69&pages=1421-1432&publication_year=2005&author=Chen%2CD.&author=Daniel%2CK.%20G.&author=Chen%2CM.%20S.&author=Kuhn%2CD.%20J.&author=Landis-Piwowar%2CK.%20R.&author=Dou%2CQ.%20P. earning monthly?
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18038912 each month?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Mechanism%20of%20apoptosis%20induced%20by%20apigenin%20in%20HepG2%20human%20hepatoma%20cells%3A%20involvement%20of%20reactive%20oxygen%20species%20generated%20by%20NADPH%20oxidase&journal=Arch.%20Pharm.%20Res.&doi=10.1007%2FBF02980274&volume=30&pages=1328-1335&publication_year=2007&author=Choi%2CS.%20I.&author=Jeong%2CC.%20S.&author=Cho%2CS.%20Y.&author=Lee%2CY.%20S.
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17449588
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Estimated%20dietary%20flavonoid%20intake%20and%20major%20food%20sources%20of%20U.S.%20adults&journal=J.%20Nutr.&volume=137&pages=1244-1252&publication_year=2007&author=Chun%2CO.%20K.&author=Chung%2CS.%20J.&author=Song%2CW.%20O.?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16235994's total income per month
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20growth%2C%20induction%20of%20apoptosis%20and%20alteration%20of%20gene%20expression%20by%20tea%20polyphenols%20in%20the%20highly%20metastatic%20human%20lung%20cancer%20cell%20line%20NCI-H460&journal=Asian.%20Pac.%20J.%20Cancer.%20Prev.&volume=6&pages=326-331&publication_year=2005&author=Ganguly%2CC.&author=Saha%2CP.&author=Panda%2CC.%20K.&author=Das%2CS.?
- How much money does https://doi.org/10.1038%2Fsj.pcan.4500845 make?
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16314891
- How much does http://scholar.google.com/scholar_lookup?&title=Novel%20antiproliferative%20flavonoids%20induce%20cell%20cycle%20arrest%20in%20human%20prostate%20cancer%20cell%20lines&journal=Prostate.%20Cancer.%20Prostatic.%20Dis.&doi=10.1038%2Fsj.pcan.4500845&volume=9&pages=68-76&publication_year=2006&author=Haddad%2CA.%20Q.&author=Venkateswaran%2CV.&author=Viswanathan%2CL.&author=Teahan%2CS.%20J.&author=Fleshner%2CN.%20E.&author=Klotz%2CL.%20H. pull in monthly?
- What's the monthly money flow for https://doi.org/10.1089%2Fjmf.2005.8.469?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16379557 produce monthly?
- Get to know http://scholar.google.com/scholar_lookup?&title=Anticancer%20activities%20of%20pomegranate%20extracts%20and%20genistein%20in%20human%20breast%20cancer%20cells&journal=J.%20Med.%20Food.&doi=10.1089%2Fjmf.2005.8.469&volume=8&pages=469-475&publication_year=2005&author=Jeune%2CM.%20A.&author=Kumi%2CJ.%20D.&author=Brown%2CJ.'s earnings
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18087801 rake in every month?
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Structural%20requirements%20of%202%E2%80%B2%2C4%E2%80%B2%2C6%E2%80%B2-tris%28methoxymethoxy%29%20chalcone%20derivatives%20for%20anti-inflammatory%20activity%3A%20the%20importance%20of%20a%202%E2%80%B2-hydroxy%20moiety&journal=Arch.%20Pharm.%20Res.&doi=10.1007%2FBF02977357&volume=30&pages=1359-1367&publication_year=2007&author=Jin%2CF.&author=Jin%2CX.%20Y.&author=Jin%2CY.%20L.&author=Sohn%2CD.%20W.&author=Kim%2CS.%20A.&author=Sohn%2CD.%20H.&author=Kim%2CY.%20C.&author=Kim%2CH.%20S.
- What's the financial gain of https://doi.org/10.1017%2FS1368980006009712?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17125569
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Age-related%20variations%20in%20flavonoid%20intake%20and%20sources%20in%20the%20Australian%20population&journal=Public.%20Health.%20Nutr.&doi=10.1017%2FS1368980006009712&volume=9&pages=1045-1054&publication_year=2006&author=Johannot%2CL.&author=Somerset%2CS.%20M.?
- How much does https://doi.org/10.1016%2Fj.leukres.2006.08.019 gross monthly?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17007926
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Scutellaria%20baicalensis%2C%20a%20herbal%20medicine%3A%20anti-proliferative%20and%20apoptotic%20activity%20against%20acute%20lymphocytic%20leukemia%2C%20lymphoma%20and%20myeloma%20cell%20lines&journal=Leuk.%20Res.&doi=10.1016%2Fj.leukres.2006.08.019&volume=31&pages=523-530&publication_year=2007&author=Kumagai%2CT.&author=Muller%2CC.%20I.&author=Desmond%2CJ.%20C.&author=Imai%2CY.&author=Heber%2CD.&author=Koeffler%2CH.%20P.
- What's https://doi.org/10.1152%2Fajpgi.00248.2006's gross income?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Induction%20of%20cell%20cycle%20arrest%20and%20apoptosis%20in%20HT-29%20human%20colon%20cancer%20cells%20by%20the%20dietary%20compound%20luteolin&journal=Am.%20J.%20Physiol.%20Gastrointest.%20Liver.%20Physiol.&doi=10.1152%2Fajpgi.00248.2006&volume=292&pages=G66-G75&publication_year=2007&author=Lim%2CY.&author=Jeong%2CY.&author=Tyner%2CA.%20L.&author=Park%2CJ.%20H. making per month?
- How much money does https://doi.org/10.1016%2F0022-1759%2883%2990303-4 generate?
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=6606682
- Earnings of http://scholar.google.com/scholar_lookup?&title=Rapid%20colorimetric%20assay%20for%20cellular%20growth%20and%20survival%3A%20application%20to%20proliferation%20and%20cytotoxicity%20assays&journal=J.%20Immunol.%20Methods.&doi=10.1016%2F0022-1759%2883%2990303-4&volume=65&pages=55-63&publication_year=1983&author=Mosmann%2CT.
- See how much https://doi.org/10.1002%2Fijc.22499 makes per month
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17192901 generate monthly?
- Revenue of http://scholar.google.com/scholar_lookup?&title=Flavonoids%20and%20risk%20of%20squamous%20cell%20esophageal%20cancer&journal=Int.%20J.%20Cancer.&doi=10.1002%2Fijc.22499&volume=120&pages=1560-1564&publication_year=2007&author=Rossi%2CM.&author=Garavello%2CW.&author=Talamini%2CR.&author=La-Vecchia%2CC.&author=Franceschi%2CS.&author=Lagiou%2CP.&author=Zambon%2CP.&author=Dal-Maso%2CL.&author=Bosetti%2CC.&author=Negri%2CE.
- Profit of https://doi.org/10.1016%2Fj.taap.2004.02.002
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15163544 generate monthly?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Structurally%20related%20anti-cancer%20effects%20of%20flavanones%20in%20vitro%20and%20in%20vivo%3A%20involvement%20of%20caspase%203%20activation%2C%20p21%20gene%20expression%2C%20and%20reactive%20oxygen%20species%20production&journal=Toxicol.%20Appl.%20Pharmacol.&doi=10.1016%2Fj.taap.2004.02.002&volume=197&pages=84-95&publication_year=2004&author=Shen%2CS.%20C.&author=Ko%2CC.%20H.&author=Tseng%2CS.%20W.&author=Tsai%2CS.%20H.&author=Chen%2CY.%20C.?
- How much profit does https://doi.org/10.2174%2F138945006776055004 generate?
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16515531?
- How much money does http://scholar.google.com/scholar_lookup?&title=Natural%20flavonoids%20targeting%20deregulated%20cell%20cycle%20progression%20in%20cancer%20cells&journal=Curr.%20Drug.%20Targets.&doi=10.2174%2F138945006776055004&volume=7&pages=345-354&publication_year=2006&author=Singh%2CR.%20P.&author=Agarwal%2CR. make?
- Financial intake of https://doi.org/10.1016%2Fj.jada.2006.05.246
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Tea%20Consumption%20is%20a%20determinant%20of%20flavonoid%20intake%20among%20US%20adults&journal=J.%20Am.%20Diet.%20Assoc.&doi=10.1016%2Fj.jada.2006.05.246&volume=106&publication_year=2006&author=Song%2CW.%20O.&author=Chun%2CO.%20K.&author=Chung%2CS.%20C.?
- Check the income stats for https://doi.org/10.1158%2F1055-9965.EPI-06-0785
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17416758?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Dietary%20flavonoids%20and%20the%20risk%20of%20colorectal%20cancer&journal=Cancer.%20Epidemiol.%20Biomarkers.%20Prev.&doi=10.1158%2F1055-9965.EPI-06-0785&volume=16&pages=684-693&publication_year=2007&author=Theodoratou%2CE.&author=Kyle%2CJ.&author=Cetnarskyj%2CR.&author=Farrington%2CS.%20M.&author=Tenesa%2CA.&author=Barnetson%2CR.&author=Porteous%2CM.&author=Dunlop%2CM.&author=Campbell%2CH. have monthly?
- Find out how much https://doi.org/10.1002%2Fijc.22419 earns monthly
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17131309 net monthly?
- http://scholar.google.com/scholar_lookup?&title=Dietary%20polyphenolic%20phytochemicals-promising%20cancer%20chemopreventive%20agents%20in%20humans%3F%20A%20review%20of%20their%20clinical%20properties&journal=Int.%20J.%20Cancer.&doi=10.1002%2Fijc.22419&volume=120&pages=451-458&publication_year=2007&author=Thomasset%2CS.%20C.&author=Berry%2CD.%20P.&author=Garcea%2CG.&author=Marczylo%2CT.&author=Steward%2CW.%20P.&author=Gescher%2CA.%20J.'s total income per month
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16898267
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Quercetin%20induces%20p53-independent%20apoptosis%20in%20human%20prostate%20cancer%20cells%20by%20modulating%20Bcl-2-related%20proteins%3A%20a%20possible%20mediation%20by%20IGFBP-3&journal=Oncol.%20Res.&volume=16&pages=67-74&publication_year=2006&author=Vijayababu%2CM.%20R.&author=Kanagaraj%2CP.&author=Arunkumar%2CA.&author=Ilangovan%2CR.&author=Dharmarajan%2CA.&author=Arunakaran%2CJ.
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17146965
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20the%20hydrophobic%20group%20on%20ring%20A%20of%20chalcones%20in%20the%20inhibition%20of%20interleukin-5&journal=Arch.%20Pharm.%20Res.&doi=10.1007%2FBF02969280&volume=29&pages=969-976&publication_year=2006&author=Yang%2CH.%20M.&author=Shin%2CH.%20R.&author=Cho%2CS.%20H.&author=Song%2CG.%20Y.&author=Lee%2CI.%20J.&author=Kim%2CM.%20K.&author=Lee%2CS.%20H.&author=Ryu%2CJ.%20C.&author=Kim%2CY.&author=Jung%2CS.%20H.?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17424936?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Topisomerase%20I%20inhibition%20and%20cytotoxicity%20of%20licochalcones%20A%20and%20E%20from%20Glycyrrhiza%20inflata&journal=Arch.%20Pharm.%20Res.&doi=10.1007%2FBF02977611&volume=30&pages=313-316&publication_year=2007&author=Yoon%2CG.&author=Kang%2CB.%20Y.&author=Cheon%2CS.%20H.?
- See how much https://citation-needed.springer.com/v2/references/10.1007/s12272-001-1280-8?format=refman&flavour=references makes per month
- What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hui%20Chang each month?
- Monthly income for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hui%20Chang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mantian%20Mi bring in each month?
- Profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mantian%20Mi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Learn about the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Wenhua%20Ling
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Wenhua%20Ling%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jundong%20Zhu?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jundong%20Zhu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
- Profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qianyong%20Zhang
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qianyong%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Na%20Wei?
- What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Na%20Wei%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
- How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yong%20Zhou have monthly?
- What's the monthly money flow for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yong%20Zhou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yong%20Tang?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yong%20Tang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jialin%20Yuan
- How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jialin%20Yuan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
- How much does https://s100.copyright.com/AppDispatchServlet?title=Structurally%20related%20cytotoxic%20effects%20of%20flavonoids%20on%20human%20cancer%20cells%20in%20vitro&author=Hui%20Chang%20et%20al&contentID=10.1007%2Fs12272-001-1280-8©right=The%20Pharmaceutical%20Society%20of%20Korea&publication=0253-6269&publicationDate=2009-04-30&publisherName=SpringerNature&orderBeanReset=true net monthly?
- What is the earnings of https://citation-needed.springer.com/v2/references/10.1007/s12272-001-1280-8?format=refman&flavour=citation?
- How much cash flow does https://authorservices.springernature.com/go/sn/?utm_source=SNLinkfooter&utm_medium=Web&utm_campaign=SNReferral have monthly?
- Explore the financials of https://www.springernature.com/gp/open-research/about/the-fundamentals-of-open-access-and-open-research
- Earnings of https://www.springernature.com/gp/products
- What's the financial gain of https://www.springernature.com/gp/librarians?
- https://www.springernature.com/gp/societies's revenue stream
- What is the earnings of https://www.springernature.com/gp/partners?
- How much does https://www.springer.com/ net monthly?
- What's the financial gain of https://www.nature.com/?
- Income figures for https://www.biomedcentral.com/
- What's the financial intake of https://www.palgrave.com/?
- How much does https://www.apress.com/ earn?
- How much does https://www.springernature.com/gp/legal/ccpa make?
- What's the financial outcome of https://www.springernature.com/gp/info/accessibility?
- Financial intake of https://support.springernature.com/en/support/home
- How profitable is https://support.springernature.com/en/support/solutions/articles/6000255911-subscription-cancellations?
- How profitable is https://www.springernature.com/?
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Clipboard.js
- Prism.js
CDN Services {π¦}
- Crossref