Here's how LINK.SPRINGER.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. Social Networks
  11. External Links
  12. Analytics And Tracking
  13. Libraries
  14. CDN Services

We are analyzing https://link.springer.com/article/10.1007/s12265-025-10630-1.

Title:
Exercise Empowerment: A Multifaceted Anatomy in Managing Diabetic Myocardial Disorder | Journal of Cardiovascular Translational Research
Description:
Diabetic myocardial disorder is characterized by myocardial dysfunction in diabetes mellitus patients, independent of other heart disease causes like coronary artery disease or hypertension. This condition threatens the well-being of patients. At the cellular and molecular levels, disruptions in cardiomyocyte metabolism, abnormal calcium signaling, and increased reactive oxygen species production, among others, interconnect to create a complex pathological network that worsens myocardial cell damage and leads to cardiac dysfunction symptoms. The limited effectiveness of current pharmacological treatments has increased the appeal of non-pharmacological therapies, especially exercise therapy. Exercise is anticipated to ameliorate diabetic myocardial disease through pleiotropic beneficial effects. The fundamental mechanisms behind these benefits remain unclear; further investigation of these mechanisms will aid in developing targeted therapies. This paper aims to explore how exercise affects myocardial metabolism, antioxidant capacity, fibrosis, and microangiopathy while providing an overview of key mechanisms and recent breakthroughs to encourage ongoing research in this area. Graphical Abstract Exercise integrates these independent mechanisms and interacts to mitigate disease processes, including cardiomyocyte metabolism, oxidative stress, myocardial fibrosis, and microangiopathy.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

  • Health & Fitness
  • Education
  • Fitness & Wellness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We find it hard to spot revenue streams.

Many websites are intended to earn money, but some serve to share ideas or build connections. Websites exist for all kinds of purposes. This might be one of them. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {🔍}

pubmed, article, google, scholar, cas, diabetic, cardiomyopathy, central, exercise, mitochondrial, diabetes, wang, cardiac, httpsdoiorgs, res, myocardial, heart, physiol, zhang, chen, dysfunction, type, function, mechanisms, oxidative, cell, mol, sci, disease, fibrosis, stress, training, metabolism, med, liu, mice, role, cardiovascular, therapeutic, rats, httpsdoiorg, oxygen, protein, receptor, endothelial, httpsdoiorgcircresaha, cardiovasc, biol, cardiol, rev,

Topics {✒️}

parkin-ubiquitin-p62-mediated mitochondrial priming inhibiting tgf-β1/smad pathways mir-486a-5p-mst1 pathway high-intensity interval training activating pink1/parkin-mediated mitophagy ampk/sirt1/pgc-1α pathway renin-angiotensin-aldosterone signaling systems moderate-intensity continuous training month download article/chapter tgf-β1/smad pathway age-rage/hmgb-1 signaling pathway high-fat diet pkc-mapk signalling pathways transforming growth factor-β transforming growth factor–β foxo3a-parkin-mediated mitophagy insulin-resistance-induced heart disease angiotensin receptor–neprilysin inhibitor inducing beta2-adrenergic receptors isoproterenol-induced pathological remodeling renin-angiotensin-aldosterone system renin–angiotensin–aldosterone system aquatic‐based exercise program pgc-1α-mediated regulation endurance exercise-induced elevation evidence-based risk assessment stz-induced diabetic mice streptozotocin-induced diabetic cardiomyopathy gov/books/nbk581934/ yilmaz multiple enzyme-mimicking activities streptozotocin-induced diabetic mice streptozotocin-induced diabetic rats fatty acid uptake receptor-activated smads targeting mir-551b-5p ros-induced ros release protein o-glcnacylation pi3k/akt/enos pathway aerobic exercise-based prevention diet-induced obesity diabetic myocardial disorder ob/ob mouse heart myocardial reperfusion injury plasmic reticulum ca2+-atpase metabolically challenged myocytes/hearts full article pdf hyperglycemia-induced cardiovascular complications reactive oxygen species nuclear factor κb skeletal muscle mitochondria

Questions {❓}

  • Cardiac Microvascular Dysfunction and Cardiomyopathy in Diabetes: Is Ferroptosis a Therapeutic Target?
  • Diabetic Cardiomyopathy: What is it and can it be fixed?
  • Emerging Actors in Diabetic Cardiomyopathy: Heartbreaker Biomarkers or Therapeutic Targets?
  • Physical Exercise and Its Protective Effects on Diabetic Cardiomyopathy: What Is the Evidence?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Exercise Empowerment: A Multifaceted Anatomy in Managing Diabetic Myocardial Disorder
         description:Diabetic myocardial disorder is characterized by myocardial dysfunction in diabetes mellitus patients, independent of other heart disease causes like coronary artery disease or hypertension. This condition threatens the well-being of patients. At the cellular and molecular levels, disruptions in cardiomyocyte metabolism, abnormal calcium signaling, and increased reactive oxygen species production, among others, interconnect to create a complex pathological network that worsens myocardial cell damage and leads to cardiac dysfunction symptoms. The limited effectiveness of current pharmacological treatments has increased the appeal of non-pharmacological therapies, especially exercise therapy. Exercise is anticipated to ameliorate diabetic myocardial disease through pleiotropic beneficial effects. The fundamental mechanisms behind these benefits remain unclear; further investigation of these mechanisms will aid in developing targeted therapies. This paper aims to explore how exercise affects myocardial metabolism, antioxidant capacity, fibrosis, and microangiopathy while providing an overview of key mechanisms and recent breakthroughs to encourage ongoing research in this area. Exercise integrates these independent mechanisms and interacts to mitigate disease processes, including cardiomyocyte metabolism, oxidative stress, myocardial fibrosis, and microangiopathy.
         datePublished:2025-06-04T00:00:00Z
         dateModified:2025-06-04T00:00:00Z
         pageStart:1
         pageEnd:28
         sameAs:https://doi.org/10.1007/s12265-025-10630-1
         keywords:
            Diabetic myocardial disorder
            Exercise
            Myocardial metabolism
            Oxidative stress
            Myocardial fibrosis
            Microangiopathy
            Cardiology
            Human Genetics
            Biomedical Engineering and Bioengineering
            Biomedicine
            general
            Medicine/Public Health
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Figa_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig4_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig5_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig6_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig7_HTML.png
         isPartOf:
            name:Journal of Cardiovascular Translational Research
            issn:
               1937-5395
               1937-5387
            type:
               Periodical
         publisher:
            name:Springer US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Congfei Chen
               affiliation:
                     name:Tianjin University of Sport
                     address:
                        name:Tianjin Key Laboratory of Exercise Physiology & Sports Medicine, Tianjin University of Sport, Tianjin, China
                        type:PostalAddress
                     type:Organization
                     name:Military Medical Sciences Academy
                     address:
                        name:Military Medical Sciences Academy, Tianjin, P. R. China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Longfei Xu
               affiliation:
                     name:Military Medical Sciences Academy
                     address:
                        name:Military Medical Sciences Academy, Tianjin, P. R. China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Kun Wang
               affiliation:
                     name:Military Medical Sciences Academy
                     address:
                        name:Military Medical Sciences Academy, Tianjin, P. R. China
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Tianhui Wang
               url:http://orcid.org/0000-0003-2530-1101
               affiliation:
                     name:Military Medical Sciences Academy
                     address:
                        name:Military Medical Sciences Academy, Tianjin, P. R. China
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Exercise Empowerment: A Multifaceted Anatomy in Managing Diabetic Myocardial Disorder
      description:Diabetic myocardial disorder is characterized by myocardial dysfunction in diabetes mellitus patients, independent of other heart disease causes like coronary artery disease or hypertension. This condition threatens the well-being of patients. At the cellular and molecular levels, disruptions in cardiomyocyte metabolism, abnormal calcium signaling, and increased reactive oxygen species production, among others, interconnect to create a complex pathological network that worsens myocardial cell damage and leads to cardiac dysfunction symptoms. The limited effectiveness of current pharmacological treatments has increased the appeal of non-pharmacological therapies, especially exercise therapy. Exercise is anticipated to ameliorate diabetic myocardial disease through pleiotropic beneficial effects. The fundamental mechanisms behind these benefits remain unclear; further investigation of these mechanisms will aid in developing targeted therapies. This paper aims to explore how exercise affects myocardial metabolism, antioxidant capacity, fibrosis, and microangiopathy while providing an overview of key mechanisms and recent breakthroughs to encourage ongoing research in this area. Exercise integrates these independent mechanisms and interacts to mitigate disease processes, including cardiomyocyte metabolism, oxidative stress, myocardial fibrosis, and microangiopathy.
      datePublished:2025-06-04T00:00:00Z
      dateModified:2025-06-04T00:00:00Z
      pageStart:1
      pageEnd:28
      sameAs:https://doi.org/10.1007/s12265-025-10630-1
      keywords:
         Diabetic myocardial disorder
         Exercise
         Myocardial metabolism
         Oxidative stress
         Myocardial fibrosis
         Microangiopathy
         Cardiology
         Human Genetics
         Biomedical Engineering and Bioengineering
         Biomedicine
         general
         Medicine/Public Health
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Figa_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig4_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig5_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig6_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12265-025-10630-1/MediaObjects/12265_2025_10630_Fig7_HTML.png
      isPartOf:
         name:Journal of Cardiovascular Translational Research
         issn:
            1937-5395
            1937-5387
         type:
            Periodical
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Congfei Chen
            affiliation:
                  name:Tianjin University of Sport
                  address:
                     name:Tianjin Key Laboratory of Exercise Physiology & Sports Medicine, Tianjin University of Sport, Tianjin, China
                     type:PostalAddress
                  type:Organization
                  name:Military Medical Sciences Academy
                  address:
                     name:Military Medical Sciences Academy, Tianjin, P. R. China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Longfei Xu
            affiliation:
                  name:Military Medical Sciences Academy
                  address:
                     name:Military Medical Sciences Academy, Tianjin, P. R. China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kun Wang
            affiliation:
                  name:Military Medical Sciences Academy
                  address:
                     name:Military Medical Sciences Academy, Tianjin, P. R. China
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Tianhui Wang
            url:http://orcid.org/0000-0003-2530-1101
            affiliation:
                  name:Military Medical Sciences Academy
                  address:
                     name:Military Medical Sciences Academy, Tianjin, P. R. China
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical"]:
      name:Journal of Cardiovascular Translational Research
      issn:
         1937-5395
         1937-5387
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Tianjin University of Sport
      address:
         name:Tianjin Key Laboratory of Exercise Physiology & Sports Medicine, Tianjin University of Sport, Tianjin, China
         type:PostalAddress
      name:Military Medical Sciences Academy
      address:
         name:Military Medical Sciences Academy, Tianjin, P. R. China
         type:PostalAddress
      name:Military Medical Sciences Academy
      address:
         name:Military Medical Sciences Academy, Tianjin, P. R. China
         type:PostalAddress
      name:Military Medical Sciences Academy
      address:
         name:Military Medical Sciences Academy, Tianjin, P. R. China
         type:PostalAddress
      name:Military Medical Sciences Academy
      address:
         name:Military Medical Sciences Academy, Tianjin, P. R. China
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Congfei Chen
      affiliation:
            name:Tianjin University of Sport
            address:
               name:Tianjin Key Laboratory of Exercise Physiology & Sports Medicine, Tianjin University of Sport, Tianjin, China
               type:PostalAddress
            type:Organization
            name:Military Medical Sciences Academy
            address:
               name:Military Medical Sciences Academy, Tianjin, P. R. China
               type:PostalAddress
            type:Organization
      name:Longfei Xu
      affiliation:
            name:Military Medical Sciences Academy
            address:
               name:Military Medical Sciences Academy, Tianjin, P. R. China
               type:PostalAddress
            type:Organization
      name:Kun Wang
      affiliation:
            name:Military Medical Sciences Academy
            address:
               name:Military Medical Sciences Academy, Tianjin, P. R. China
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Tianhui Wang
      url:http://orcid.org/0000-0003-2530-1101
      affiliation:
            name:Military Medical Sciences Academy
            address:
               name:Military Medical Sciences Academy, Tianjin, P. R. China
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Tianjin Key Laboratory of Exercise Physiology & Sports Medicine, Tianjin University of Sport, Tianjin, China
      name:Military Medical Sciences Academy, Tianjin, P. R. China
      name:Military Medical Sciences Academy, Tianjin, P. R. China
      name:Military Medical Sciences Academy, Tianjin, P. R. China
      name:Military Medical Sciences Academy, Tianjin, P. R. China
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(837)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

CDN Services {📦}

  • Crossref

6.25s.