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LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. CDN Services

We are analyzing https://link.springer.com/article/10.1007/s12032-025-02752-y.

Title:
Exosomal miRNA-based theranostics in cervical cancer: bridging diagnostics and therapy | Medical Oncology
Description:
Cervical cancer (CC) remains a significant global health burden, particularly in low- and middle-income countries, where access to effective screening and treatment is limited. Despite advancements in conventional therapies, such as surgery, chemotherapy, and radiotherapy, challenges related to late-stage diagnosis, treatment resistance, and disease recurrence persist. The emergence of microRNAs (miRNAs) as key regulators of gene expression has revolutionized cancer diagnostics and therapeutics. Exosomal miRNAs, in particular, have garnered attention due to their stability, detectability in bodily fluids, and pivotal roles in tumor progression, metastasis, and immune modulation. This review provides a comprehensive overview of the role of exosomal miRNAs in the theranostic landscape of CC. We explore their involvement in disease pathogenesis, highlighting their potential as minimally invasive diagnostic biomarkers for early detection and disease monitoring. Furthermore, we examine their utility in therapeutic strategies, including miRNA-mediated drug delivery systems and miRNA-targeted interventions to overcome chemoresistance. Integrating exosomal miRNA profiling with current diagnostic modalities could enhance screening sensitivity and specificity, while miRNA-based therapies offer novel avenues to improve treatment efficacy. This review discusses recent advancements in miRNA research, current challenges in clinical translation, and future perspectives on leveraging exosomal miRNAs for personalized CC care.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Link.springer.com might be plotting its profit, but the way they're doing it isn't detectable yet.

Keywords {🔍}

pubmed, article, google, scholar, cancer, cas, central, cervical, mol, wang, therapy, mirna, zhang, oncol, mirnas, microrna, role, liu, review, cell, therapeutic, int, cells, resistance, chen, sci, targeting, metastasis, drug, delivery, httpsdoiorgs, rev, micrornas, biomarkers, tumor, zhou, human, potential, diagnostic, res, exosomal, therapeutics, progression, development, front, huang, ther, treatment, cancers, analysis,

Topics {✒️}

omar awad alsaidan promoting palmitoleic-acid-mediated ferroptosis exosomal mirna-based theranostics immuno-micro-rnas mir-146a droplet-based digital pcr month download article/chapter mirna-derivative nucleotide drugs rationalizing epigenetics-based therapies mir-182-5p/foxo1 pathway personalized cc care mirna-based therapies offer real-time pcr circrna-mirna-mrna regulatory network campos-viguri ge exosome-based liquid biopsies pi3k/akt/mtor pathway pax1/znf582 methylation detection cell-derived biomimetic nanocarriers multi-target specific therapeutics contemp oncol/współczesna onkologia mir-15a-3p enhances nano-based chemotherapeutics delivery emt-induced immune evasion inhibiting cell-cycle progression targeting slug/zeb2 signaling worldwide country-level analysis single-cell analysis tools comprehensive view cancer-derived exosomal mir-651 tumor-derived exosomes enriched crit rev oncol/hematol full article pdf regulating mir-4429/mbd1 axis genome-wide microrna analysis el-husseiny aa adopting circulating mirna targeting pd-1/pd-l1 nanoparticles-based strategies real-time detection vivo mirna imaging tumor microenvironment-derived exosomes mir-155-5p accelerates mechanism-based cancer therapy chemically modified platforms hassan ha mirna-based therapeutics article number 193 kabekkodu sp squamous cell carcinoma epithelial-mesenchymal transition

Questions {❓}

  • Can cisplatin therapy be improved?
  • MicroRNA function in cancer: oncogene or a tumor suppressor?
  • Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?

Schema {🗺️}

WebPage:
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         headline:Exosomal miRNA-based theranostics in cervical cancer: bridging diagnostics and therapy
         description:Cervical cancer (CC) remains a significant global health burden, particularly in low- and middle-income countries, where access to effective screening and treatment is limited. Despite advancements in conventional therapies, such as surgery, chemotherapy, and radiotherapy, challenges related to late-stage diagnosis, treatment resistance, and disease recurrence persist. The emergence of microRNAs (miRNAs) as key regulators of gene expression has revolutionized cancer diagnostics and therapeutics. Exosomal miRNAs, in particular, have garnered attention due to their stability, detectability in bodily fluids, and pivotal roles in tumor progression, metastasis, and immune modulation. This review provides a comprehensive overview of the role of exosomal miRNAs in the theranostic landscape of CC. We explore their involvement in disease pathogenesis, highlighting their potential as minimally invasive diagnostic biomarkers for early detection and disease monitoring. Furthermore, we examine their utility in therapeutic strategies, including miRNA-mediated drug delivery systems and miRNA-targeted interventions to overcome chemoresistance. Integrating exosomal miRNA profiling with current diagnostic modalities could enhance screening sensitivity and specificity, while miRNA-based therapies offer novel avenues to improve treatment efficacy. This review discusses recent advancements in miRNA research, current challenges in clinical translation, and future perspectives on leveraging exosomal miRNAs for personalized CC care.
         datePublished:2025-05-04T00:00:00Z
         dateModified:2025-05-04T00:00:00Z
         pageStart:1
         pageEnd:23
         sameAs:https://doi.org/10.1007/s12032-025-02752-y
         keywords:
            Exosomal miRNA
            Cervical cancer
            Theranostics
            Biomarkers
            Targeted therapy
            Personalized medicine
            miRNA therapeutics
            Oncology
            Hematology
            Pathology
            Internal Medicine
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                     address:
                        name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
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                     address:
                        name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
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                        name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
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                     address:
                        name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
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                     name:Prince Sattam Bin Abdulaziz University
                     address:
                        name:Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
                        type:PostalAddress
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               name:Mohammad Fareed
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                     name:AlMaarefa University
                     address:
                        name:Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia
                        type:PostalAddress
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               name:Bhupendra Prajapati
               url:http://orcid.org/0000-0001-8242-4541
               affiliation:
                     name:Ganpat University
                     address:
                        name:Department of Pharmaceutics and Pharmaceutical Technology, Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mahesana, India
                        type:PostalAddress
                     type:Organization
                     name:Silpakorn University
                     address:
                        name:Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
                        type:PostalAddress
                     type:Organization
                     name:Chitkara University
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                        name:Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, India
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ScholarlyArticle:
      headline:Exosomal miRNA-based theranostics in cervical cancer: bridging diagnostics and therapy
      description:Cervical cancer (CC) remains a significant global health burden, particularly in low- and middle-income countries, where access to effective screening and treatment is limited. Despite advancements in conventional therapies, such as surgery, chemotherapy, and radiotherapy, challenges related to late-stage diagnosis, treatment resistance, and disease recurrence persist. The emergence of microRNAs (miRNAs) as key regulators of gene expression has revolutionized cancer diagnostics and therapeutics. Exosomal miRNAs, in particular, have garnered attention due to their stability, detectability in bodily fluids, and pivotal roles in tumor progression, metastasis, and immune modulation. This review provides a comprehensive overview of the role of exosomal miRNAs in the theranostic landscape of CC. We explore their involvement in disease pathogenesis, highlighting their potential as minimally invasive diagnostic biomarkers for early detection and disease monitoring. Furthermore, we examine their utility in therapeutic strategies, including miRNA-mediated drug delivery systems and miRNA-targeted interventions to overcome chemoresistance. Integrating exosomal miRNA profiling with current diagnostic modalities could enhance screening sensitivity and specificity, while miRNA-based therapies offer novel avenues to improve treatment efficacy. This review discusses recent advancements in miRNA research, current challenges in clinical translation, and future perspectives on leveraging exosomal miRNAs for personalized CC care.
      datePublished:2025-05-04T00:00:00Z
      dateModified:2025-05-04T00:00:00Z
      pageStart:1
      pageEnd:23
      sameAs:https://doi.org/10.1007/s12032-025-02752-y
      keywords:
         Exosomal miRNA
         Cervical cancer
         Theranostics
         Biomarkers
         Targeted therapy
         Personalized medicine
         miRNA therapeutics
         Oncology
         Hematology
         Pathology
         Internal Medicine
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         name:Springer US
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            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Neha R. Raghani
            url:http://orcid.org/0000-0002-4224-2900
            affiliation:
                  name:Saraswati Institute of Pharmaceutical Sciences
                  address:
                     name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mehul R. Chorawala
            url:http://orcid.org/0000-0002-3724-0986
            affiliation:
                  name:Opp. Gujarat University
                  address:
                     name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Kavya Parekh
            url:http://orcid.org/0009-0009-3110-2759
            affiliation:
                  name:Opp. Gujarat University
                  address:
                     name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Anvesha Sharma
            url:http://orcid.org/0009-0008-9094-1889
            affiliation:
                  name:Saraswati Institute of Pharmaceutical Sciences
                  address:
                     name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Omar Awad Alsaidan
            url:http://orcid.org/0000-0002-2848-2932
            affiliation:
                  name:Jouf University
                  address:
                     name:Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Prawez Alam
            url:http://orcid.org/0000-0002-7632-3426
            affiliation:
                  name:Prince Sattam Bin Abdulaziz University
                  address:
                     name:Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mohammad Fareed
            affiliation:
                  name:AlMaarefa University
                  address:
                     name:Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bhupendra Prajapati
            url:http://orcid.org/0000-0001-8242-4541
            affiliation:
                  name:Ganpat University
                  address:
                     name:Department of Pharmaceutics and Pharmaceutical Technology, Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mahesana, India
                     type:PostalAddress
                  type:Organization
                  name:Silpakorn University
                  address:
                     name:Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
                     type:PostalAddress
                  type:Organization
                  name:Chitkara University
                  address:
                     name:Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, India
                     type:PostalAddress
                  type:Organization
            email:[email protected]
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      issn:
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      volumeNumber:42
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      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Saraswati Institute of Pharmaceutical Sciences
      address:
         name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
         type:PostalAddress
      name:Opp. Gujarat University
      address:
         name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
         type:PostalAddress
      name:Opp. Gujarat University
      address:
         name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
         type:PostalAddress
      name:Saraswati Institute of Pharmaceutical Sciences
      address:
         name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
         type:PostalAddress
      name:Jouf University
      address:
         name:Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia
         type:PostalAddress
      name:Prince Sattam Bin Abdulaziz University
      address:
         name:Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
         type:PostalAddress
      name:AlMaarefa University
      address:
         name:Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia
         type:PostalAddress
      name:Ganpat University
      address:
         name:Department of Pharmaceutics and Pharmaceutical Technology, Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mahesana, India
         type:PostalAddress
      name:Silpakorn University
      address:
         name:Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
         type:PostalAddress
      name:Chitkara University
      address:
         name:Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, India
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Neha R. Raghani
      url:http://orcid.org/0000-0002-4224-2900
      affiliation:
            name:Saraswati Institute of Pharmaceutical Sciences
            address:
               name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
               type:PostalAddress
            type:Organization
      name:Mehul R. Chorawala
      url:http://orcid.org/0000-0002-3724-0986
      affiliation:
            name:Opp. Gujarat University
            address:
               name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Kavya Parekh
      url:http://orcid.org/0009-0009-3110-2759
      affiliation:
            name:Opp. Gujarat University
            address:
               name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
               type:PostalAddress
            type:Organization
      name:Anvesha Sharma
      url:http://orcid.org/0009-0008-9094-1889
      affiliation:
            name:Saraswati Institute of Pharmaceutical Sciences
            address:
               name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
               type:PostalAddress
            type:Organization
      name:Omar Awad Alsaidan
      url:http://orcid.org/0000-0002-2848-2932
      affiliation:
            name:Jouf University
            address:
               name:Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia
               type:PostalAddress
            type:Organization
      name:Prawez Alam
      url:http://orcid.org/0000-0002-7632-3426
      affiliation:
            name:Prince Sattam Bin Abdulaziz University
            address:
               name:Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
               type:PostalAddress
            type:Organization
      name:Mohammad Fareed
      affiliation:
            name:AlMaarefa University
            address:
               name:Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia
               type:PostalAddress
            type:Organization
      name:Bhupendra Prajapati
      url:http://orcid.org/0000-0001-8242-4541
      affiliation:
            name:Ganpat University
            address:
               name:Department of Pharmaceutics and Pharmaceutical Technology, Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mahesana, India
               type:PostalAddress
            type:Organization
            name:Silpakorn University
            address:
               name:Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
               type:PostalAddress
            type:Organization
            name:Chitkara University
            address:
               name:Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, India
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
      name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
      name:Department of Pharmacology and Pharmacy Practice, L. M. College of Pharmacy, Opp. Gujarat University, Ahmedabad, India
      name:Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar, India
      name:Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia
      name:Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
      name:Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia
      name:Department of Pharmaceutics and Pharmaceutical Technology, Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mahesana, India
      name:Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
      name:Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, India
WebPageElement:
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      cssSelector:.main-content

External Links {🔗}(896)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Backbone.js
  • Clipboard.js
  • Particles.js
  • Prism.js

CDN Services {📦}

  • Crossref

5.44s.