We are analyzing https://link.springer.com/article/10.1007/s12011-010-8625-1.

Title:
A Comparative Study of the Oxidative Profile in Graves’ Disease, Hashimoto’s Thyroiditis, and Papillary Thyroid Cancer | Biological Trace Element Research
Description:
The aim of this study was to evaluate and compare the oxidative profiles of three thyroid disorders: Graves’ disease (GD), Hashimoto thyroiditis (HT), and papillary thyroid cancer (PTC). Malondialdehyde levels (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) activities were examined in the plasma of 52 patients (29 untreated HT, 16 untreated GD, and 7 PTC who underwent surgical therapy). Results were compared with those of 30 healthy controls and among the three groups of patients. The GD, HT, and PTC patients exhibited increased plasma MDA levels and SOD activities compared with the controls (p < 0.05, p < 0.05, and p < 0.001, respectively). CAT activities significantly increased only for the PTC and HT patients (p < 0.001 and p < 0.05, respectively), whereas GPx activities significantly decreased only in the GD and PTC (p < 0.05 and p < 0.01, respectively). The comparison among the three groups of patients has shown increased MDA level and SOD activity for the PTC patients as compared to the GD patients (p < 0.01 and p < 0.001, respectively). Compared with HT, PTC patients exhibited significant higher MDA level, SOD, and CAT activities and a significant lower GPx activity (p < 0.01, p < 0.001, p < 0.05, and p < 0.05, respectively). No significant discrepancies were noted between the GD and HT patients. Our results have clearly shown an oxidative profile that is highly disturbed for the PTC patients as compared to those of autoimmune disorders. Future studies are needed to determine whether or not the oxidative stress has a prognostic value in this pathology.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Education
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,642,828 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure how the site profits.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {🔍}

article, google, scholar, thyroid, cas, patients, oxidative, pubmed, disease, cancer, stress, papillary, ptc, graves, sfax, content, thyroiditis, lassoued, glutathione, superoxide, autoimmune, tunisia, privacy, cookies, research, mda, sod, activities, compared, activity, access, carcinoma, free, antioxidant, clin, lipid, endocrinol, information, journal, publish, search, trace, study, saloua, mseddi, mnif, hashimoto, peroxidase, gpx, dismutase,

Topics {✒️}

month download article/chapter microsomal lipid peroxidation papillary thyroid cancer auto-immune thyroid disease papillary thyroid carcinoma related subjects lipid peroxidation thyroid papillary microcarcinoma thyroid cancer patients full article pdf superoxide dismutase glutathione peroxidase nunez de castro endocrine organs superoxide anion radical superoxide radical generation privacy choices/manage cookies plasma glutathione concentration mohamed abid mol cell endocrinol autoimmune thyroid disease experimental hyperthyroid state chu habib bourguiba thyroid activity variations check access instant access thyroid cancer antioxidant system cellular immune responses hashimoto thyroiditis chu hedi chaker papillary carcinoma european economic area hatem masmoudi tri-iodothyronin ros normal physiological functions ischemia/reperfusion insult body mass index free radical damage free radical activity fatma mnif conditions privacy policy cytochrome p450 content antioxidant defense mechanisms article lassoued accepting optional cookies oxidizing-stress parameters underwent surgical therapy functional metallothionein isoforms thyroid disease

Schema {🗺️}

WebPage:
      mainEntity:
         headline:A Comparative Study of the Oxidative Profile in Graves’ Disease, Hashimoto’s Thyroiditis, and Papillary Thyroid Cancer
         description:The aim of this study was to evaluate and compare the oxidative profiles of three thyroid disorders: Graves’ disease (GD), Hashimoto thyroiditis (HT), and papillary thyroid cancer (PTC). Malondialdehyde levels (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) activities were examined in the plasma of 52 patients (29 untreated HT, 16 untreated GD, and 7 PTC who underwent surgical therapy). Results were compared with those of 30 healthy controls and among the three groups of patients. The GD, HT, and PTC patients exhibited increased plasma MDA levels and SOD activities compared with the controls (p < 0.05, p < 0.05, and p < 0.001, respectively). CAT activities significantly increased only for the PTC and HT patients (p < 0.001 and p < 0.05, respectively), whereas GPx activities significantly decreased only in the GD and PTC (p < 0.05 and p < 0.01, respectively). The comparison among the three groups of patients has shown increased MDA level and SOD activity for the PTC patients as compared to the GD patients (p < 0.01 and p < 0.001, respectively). Compared with HT, PTC patients exhibited significant higher MDA level, SOD, and CAT activities and a significant lower GPx activity (p < 0.01, p < 0.001, p < 0.05, and p < 0.05, respectively). No significant discrepancies were noted between the GD and HT patients. Our results have clearly shown an oxidative profile that is highly disturbed for the PTC patients as compared to those of autoimmune disorders. Future studies are needed to determine whether or not the oxidative stress has a prognostic value in this pathology.
         datePublished:2010-03-05T00:00:00Z
         dateModified:2010-03-05T00:00:00Z
         pageStart:107
         pageEnd:115
         sameAs:https://doi.org/10.1007/s12011-010-8625-1
         keywords:
            Catalase
            Superoxide dismutase
            Glutathione peroxidase
            Oxidative stress
            Lipid peroxidation
            Graves’disease
            Papillary thyroid cancer
            Hashimoto thyroiditis
            Biochemistry
            general
            Biotechnology
            Nutrition
            Oncology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-010-8625-1/MediaObjects/12011_2010_8625_Fig1_HTML.gif
         isPartOf:
            name:Biological Trace Element Research
            issn:
               1559-0720
               0163-4984
            volumeNumber:138
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Humana Press Inc
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Saloua Lassoued
               affiliation:
                     name:Institut Supérieur de Biotechnologie de Sfax
                     address:
                        name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Malek Mseddi
               affiliation:
                     name:Institut Supérieur de Biotechnologie de Sfax
                     address:
                        name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Fatma Mnif
               affiliation:
                     name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
                     address:
                        name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mohamed Abid
               affiliation:
                     name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
                     address:
                        name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Fadhel Guermazi
               affiliation:
                     name:Service de médecine nucléaire, CHU Habib Bourguiba
                     address:
                        name:Service de médecine nucléaire, CHU Habib Bourguiba, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hatem Masmoudi
               affiliation:
                     name:Laboratoire d’immunologie CHU Habib Bourguiba
                     address:
                        name:Laboratoire d’immunologie CHU Habib Bourguiba, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Abdelfatteh El Feki
               affiliation:
                     name:Unité de Physiologie Animale, Faculté des Sciences de Sfax
                     address:
                        name:Unité de Physiologie Animale, Faculté des Sciences de Sfax, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hamadi Attia
               affiliation:
                     name:Institut Supérieur de Biotechnologie de Sfax
                     address:
                        name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:A Comparative Study of the Oxidative Profile in Graves’ Disease, Hashimoto’s Thyroiditis, and Papillary Thyroid Cancer
      description:The aim of this study was to evaluate and compare the oxidative profiles of three thyroid disorders: Graves’ disease (GD), Hashimoto thyroiditis (HT), and papillary thyroid cancer (PTC). Malondialdehyde levels (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) activities were examined in the plasma of 52 patients (29 untreated HT, 16 untreated GD, and 7 PTC who underwent surgical therapy). Results were compared with those of 30 healthy controls and among the three groups of patients. The GD, HT, and PTC patients exhibited increased plasma MDA levels and SOD activities compared with the controls (p < 0.05, p < 0.05, and p < 0.001, respectively). CAT activities significantly increased only for the PTC and HT patients (p < 0.001 and p < 0.05, respectively), whereas GPx activities significantly decreased only in the GD and PTC (p < 0.05 and p < 0.01, respectively). The comparison among the three groups of patients has shown increased MDA level and SOD activity for the PTC patients as compared to the GD patients (p < 0.01 and p < 0.001, respectively). Compared with HT, PTC patients exhibited significant higher MDA level, SOD, and CAT activities and a significant lower GPx activity (p < 0.01, p < 0.001, p < 0.05, and p < 0.05, respectively). No significant discrepancies were noted between the GD and HT patients. Our results have clearly shown an oxidative profile that is highly disturbed for the PTC patients as compared to those of autoimmune disorders. Future studies are needed to determine whether or not the oxidative stress has a prognostic value in this pathology.
      datePublished:2010-03-05T00:00:00Z
      dateModified:2010-03-05T00:00:00Z
      pageStart:107
      pageEnd:115
      sameAs:https://doi.org/10.1007/s12011-010-8625-1
      keywords:
         Catalase
         Superoxide dismutase
         Glutathione peroxidase
         Oxidative stress
         Lipid peroxidation
         Graves’disease
         Papillary thyroid cancer
         Hashimoto thyroiditis
         Biochemistry
         general
         Biotechnology
         Nutrition
         Oncology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-010-8625-1/MediaObjects/12011_2010_8625_Fig1_HTML.gif
      isPartOf:
         name:Biological Trace Element Research
         issn:
            1559-0720
            0163-4984
         volumeNumber:138
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Humana Press Inc
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Saloua Lassoued
            affiliation:
                  name:Institut Supérieur de Biotechnologie de Sfax
                  address:
                     name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Malek Mseddi
            affiliation:
                  name:Institut Supérieur de Biotechnologie de Sfax
                  address:
                     name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Fatma Mnif
            affiliation:
                  name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
                  address:
                     name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mohamed Abid
            affiliation:
                  name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
                  address:
                     name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Fadhel Guermazi
            affiliation:
                  name:Service de médecine nucléaire, CHU Habib Bourguiba
                  address:
                     name:Service de médecine nucléaire, CHU Habib Bourguiba, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hatem Masmoudi
            affiliation:
                  name:Laboratoire d’immunologie CHU Habib Bourguiba
                  address:
                     name:Laboratoire d’immunologie CHU Habib Bourguiba, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Abdelfatteh El Feki
            affiliation:
                  name:Unité de Physiologie Animale, Faculté des Sciences de Sfax
                  address:
                     name:Unité de Physiologie Animale, Faculté des Sciences de Sfax, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hamadi Attia
            affiliation:
                  name:Institut Supérieur de Biotechnologie de Sfax
                  address:
                     name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Biological Trace Element Research
      issn:
         1559-0720
         0163-4984
      volumeNumber:138
Organization:
      name:Humana Press Inc
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Institut Supérieur de Biotechnologie de Sfax
      address:
         name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
         type:PostalAddress
      name:Institut Supérieur de Biotechnologie de Sfax
      address:
         name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
         type:PostalAddress
      name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
      address:
         name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
         type:PostalAddress
      name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
      address:
         name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
         type:PostalAddress
      name:Service de médecine nucléaire, CHU Habib Bourguiba
      address:
         name:Service de médecine nucléaire, CHU Habib Bourguiba, Sfax, Tunisia
         type:PostalAddress
      name:Laboratoire d’immunologie CHU Habib Bourguiba
      address:
         name:Laboratoire d’immunologie CHU Habib Bourguiba, Sfax, Tunisia
         type:PostalAddress
      name:Unité de Physiologie Animale, Faculté des Sciences de Sfax
      address:
         name:Unité de Physiologie Animale, Faculté des Sciences de Sfax, Sfax, Tunisia
         type:PostalAddress
      name:Institut Supérieur de Biotechnologie de Sfax
      address:
         name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Saloua Lassoued
      affiliation:
            name:Institut Supérieur de Biotechnologie de Sfax
            address:
               name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Malek Mseddi
      affiliation:
            name:Institut Supérieur de Biotechnologie de Sfax
            address:
               name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      name:Fatma Mnif
      affiliation:
            name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
            address:
               name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      name:Mohamed Abid
      affiliation:
            name:Service d’endocrinologie interne et externe, CHU Hedi Chaker
            address:
               name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      name:Fadhel Guermazi
      affiliation:
            name:Service de médecine nucléaire, CHU Habib Bourguiba
            address:
               name:Service de médecine nucléaire, CHU Habib Bourguiba, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      name:Hatem Masmoudi
      affiliation:
            name:Laboratoire d’immunologie CHU Habib Bourguiba
            address:
               name:Laboratoire d’immunologie CHU Habib Bourguiba, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      name:Abdelfatteh El Feki
      affiliation:
            name:Unité de Physiologie Animale, Faculté des Sciences de Sfax
            address:
               name:Unité de Physiologie Animale, Faculté des Sciences de Sfax, Sfax, Tunisia
               type:PostalAddress
            type:Organization
      name:Hamadi Attia
      affiliation:
            name:Institut Supérieur de Biotechnologie de Sfax
            address:
               name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
      name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
      name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
      name:Service d’endocrinologie interne et externe, CHU Hedi Chaker, Sfax, Tunisia
      name:Service de médecine nucléaire, CHU Habib Bourguiba, Sfax, Tunisia
      name:Laboratoire d’immunologie CHU Habib Bourguiba, Sfax, Tunisia
      name:Unité de Physiologie Animale, Faculté des Sciences de Sfax, Sfax, Tunisia
      name:Unité de Biotechnologie et Pathologies, Institut Supérieur de Biotechnologie de Sfax, Sfax, Tunisia
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(106)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.26s.

LINK . SPRINGER . COM {}