We are analyzing https://link.springer.com/article/10.1007/s11882-011-0200-0.

Title:
Dietary Immunomodulatory Factors in the Development of Immune Tolerance | Current Allergy and Asthma Reports
Description:
Emerging evidence suggests that exposures during pregnancy and the early postnatal period can modify gene expression and disease propensity. Diet is a major environmental exposure, and dietary factors, including polyunsaturated fatty acids, probiotics, oligosaccharides, antioxidants, folate, and other vitamins, have effects on immune function. Some also have been implicated in reduced risk of allergy in observational studies. Intervention trials with polyunsaturated fatty acids, probiotics, and oligosaccharides suggest preliminary but as-of-yet-unconfirmed benefits. Food allergen avoidance during pregnancy, lactation, or infancy has provided no consistent evidence in allergy prevention and is no longer recommended. Rather, there is now a focus on food allergens in tolerance induction. Specific nutrients can induce changes in gene expression during early development and have been implicated in potentially heritable “epigenetic” changes in disease predisposition. Collectively, these observations emphasize that early exposures may modify tolerance development and that further research on these exposures should remain a priority.
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google, scholar, pubmed, article, allergy, cas, clin, immunol, allergic, asthma, pregnancy, early, probiotics, prevention, infants, immune, prescott, disease, risk, children, dietary, development, study, tolerance, fatty, maternal, childhood, nutr, eczema, age, folate, exp, atopy, pediatr, years, vitamin, introduction, function, supplementation, acid, foods, west, acids, reduced, trial, intake, research, factors, evidence, diet,

Topics {✒️}

long-chain fructo-oligosaccharides induces breast milk-mediated transfer dietary immunomodulatory factors month download article/chapter long-chain fructo-oligosaccharides reduced interferon-gamma secretion mitogen-activated protein kinase short-chain galacto-oligosaccharides polyunsaturated fatty acids postnatal t-cell function maternal dietary restriction neonatal immune responses early complementary feeding il-12 production article current allergy full article pdf protein kinase czeta breast-feeding protects antigen induces tolerance fatty acid composition immune tolerance published cord-blood 25-hydroxyvitamin privacy choices/manage cookies systemic immune responses rifas-shiman sl dietary factors longitudinal birth cohort dietary folate intake reduced neonatal cd4 dunstan ja medical research council food allergen avoidance human dendritic cells prebiotic galacto-oligosaccharides van esch bc retinoic acid intersect cell adh migr camargo jr ca folic acid supplements supplemental folic acid received grant support maternal dietary pattern complementary feeding innate immune function child health research major environmental exposure maternal folate levels asthma reports aims modify tolerance development curr opin pediatr

Questions {❓}

Antioxidants and allergic disease: a case of too little or too much?
Can early introduction of egg prevent egg allergy in infants?
The association between atopy and factors influencing folate metabolism: is low folate status causally related to the development of atopy?

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