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Keywords {🔍}

pubmed, article, google, scholar, cas, central, aging, wang, zhang, data, hypertension, vascular, hebei, sirt, cell, curation, signaling, pathway, res, heart, httpsdoiorgs, rats, senescence, endothelial, canagliflozin, aortic, expression, sci, shijiazhuang, china, premature, cana, int, cells, mol, department, peoples, republic, hospital, software, dahl, guo, blood, sirtuin, access, liu, kidney, disease, general, privacy,

Topics {✒️}

mir-126a-3p targets hif-1alpha p53/mirnas/ccna2 pathway serves wnt/β-catenin signaling induces regulating sirt6/hif-1alpha axis hypoxia-induced pulmonary hypertension modulating hypoxia-induced chemokine canonical p53/p21 pathway sirt6/hif-1α pathway age-treated endothelial cells month download article/chapter d-galactose-induced liver hif-1alpha/pdk4 signaling pi3k/akt signaling pathways p53/p21-independent manner high-salt-fed rats hypoxia-inducible factor-1alpha hypoxia-inducible factor 1α sodium-glucose cotransporter-2 inhibitors dahl salt-sensitive rats sirt6/ho-1 signaling long-term medical burdens heart salt-specific overexpression male dahl salt-sensitive vascular endothelial cells p53/p21 pathway 8% high-salt diet high-salt diet cellular biochemistry aims sirt6 promotes angiogenesis endothelial senescence contributes ampk-dependent pathway metalloproteinase-9tissue inhibitor high-salt intake sodium-glucose cotransporter 2 salt-sensitive hypertension regulating hif-1α abdominal aortic aneurysm full article pdf premature vascular aging sirt6 regulates autophagy hypoxic pulmonary hypertension high sodium intake p53/p21/p16 large arterial stiffness mesenchymal stem cells hypertensive heart failure physical examination center sirt1–pten signaling privacy choices/manage cookies hif-1α transgene

Questions {❓}

• Adam CA, Anghel R, Marcu DTM et al (2022) Impact of sodium-glucose cotransporter 2 (SGLT2) inhibitors on arterial stiffness and vascular aging-What do we know so far?
• Scisciola L, Olivieri F, Ambrosino C et al (2023) On the wake of metformin: do anti-diabetic SGLT2 inhibitors exert anti-aging effects?

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               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Yi Liang
      affiliation:
            name:Hebei Medical University
            address:
               name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
            name:Hebei General Hospital
            address:
               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Qingjuan Zuo
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Lili He
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Tingting Zhang
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Zhongli Wang
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Physical Examination Center, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Jianlong Zhai
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Boce Cao
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Sai Ma
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Internal Medicine, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Guorui Zhang
      affiliation:
            name:Hebei Medical University
            address:
               name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
            name:The Third Hospital of Shijiazhuang City Affiliated to Hebei Medical University
            address:
               name:Department of Cardiology, The Third Hospital of Shijiazhuang City Affiliated to Hebei Medical University, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Fan Lu
      affiliation:
            name:Hebei Medical University
            address:
               name:Department of Physiology, Hebei Medical University, Hebei, China
               type:PostalAddress
            type:Organization
      name:Kaichuan He
      affiliation:
            name:Hebei General Hospital
            address:
               name:Hebei Key Laboratory of Metabolic Diseases, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Yan Wang
      affiliation:
            name:Hebei General Hospital
            address:
               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      name:Yifang Guo
      affiliation:
            name:Hebei Medical University
            address:
               name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
            name:Hebei General Hospital
            address:
               name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Physical Examination Center, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Internal Medicine, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
      name:Department of Cardiology, The Third Hospital of Shijiazhuang City Affiliated to Hebei Medical University, Shijiazhuang, People’s Republic of China
      name:Department of Physiology, Hebei Medical University, Hebei, China
      name:Hebei Key Laboratory of Metabolic Diseases, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
      name:Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China
      name:Department of Geriatric Cardiology, Hebei General Hospital, Shijiazhuang, People’s Republic of China
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