We are analyzing https://link.springer.com/article/10.1007/s10856-018-6027-7.

Title:
Alginate membranes loaded with hyaluronic acid and silver nanoparticles to foster tissue healing and to control bacterial contamination of non-healing wounds | Journal of Materials Science: Materials in Medicine
Description:
Chronic non-healing wounds are a clinically important problem in terms of number of patients and costs. Wound dressings such as hydrogels, hydrocolloids, polyurethane films and foams are commonly used to manage these wounds since they tend to maintain a moist environment which is shown to accelerate re-epithelialization. The use of antibacterial compounds is important in the management of wound infections. A novel wound-dressing material based on a blended matrix of the polysaccharides alginate, hyaluronic acid and Chitlac-silver nanoparticles is here proposed and its application for wound healing is examined. The manufacturing approach to obtain membranes is based on gelling, foaming and freeze-casting of alginate, hyaluronic acid and Chitlac-silver nanoparticles mixtures using calcium ions as the cross-linking agent. Comprehensive evaluations of the morphology, swelling kinetics, permeability, mechanical characteristics, cytotoxicity, capability to inhibit metalloproteinases and of antibacterial property were conducted. Biological in vitro studies demonstrated that hyaluronic acid released by the membrane is able to stimulate the wound healing meanwhile the metal silver exploits an efficient antibacterial activity against both planktonic bacteria and biofilms. Overall, the experimental data evidence that the studied material could be used as antibacterial wound dressing for wound healing promotion.
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Keywords {🔍}

article, google, scholar, wound, wounds, silver, chronic, care, healing, paoletti, marsich, travan, matrix, materials, nanoparticles, content, dressings, repair, dermatol, human, donati, mater, privacy, cookies, analysis, journal, alginate, hyaluronic, acid, antibacterial, metalloproteinases, antimicrobial, med, int, regen, sci, data, publish, research, search, membranes, tissue, bacterial, nonhealing, tarusha, hydrogels, vitro, activity, biofilms, dressing,

Topics {✒️}

month download article/chapter trevino-santa cruz mb vitamin d-mediated regulation eu-fp7 project “anastomoseal” wound-dressing material based chitlac-silver nanoparticles mixtures polysaccharide-based hydrogels wound care products advanced therapeutic dressings full article pdf privacy choices/manage cookies medical devices access alginate membranes loaded ostomy wound manag endothelial cell growth chitlac-silver nanoparticles burn care rehabil adv wound care chronic wound care european economic area cross-linking agent clin microbiol infect chitosan-tpp hydrogel assist reprod genet decidual stromal cells pig articular chondrocyte lactose modified chitosan real-time monitoring enciso-moreno ja diabetic foot ulcers piazza dell’ospitale 1 metal silver exploits chronic wound fluid chronic wound environments silver nanoparticles embedded antimicrobial membrane based wound repair regen experimental data evidence conditions privacy policy biomedical applications human melanoma cells human dermal fibroblasts nano-engineering approaches human wound fluid antibacterial wound dressing control bacterial contamination innate immune system fibroblast senescence--implications nano-composite scaffolds physical properties controlled

Schema {🗺️}

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