We are analyzing https://link.springer.com/article/10.1007/s10517-012-1876-4.

Title:
Expression of Genes of Glutathione Transferase Isoforms GSTP1-1, GSTA4-4, and GSTK1-1 in Tumor Cells during the Formation of Drug Resistance to Cisplatin | Bulletin of Experimental Biology and Medicine
Description:
We studied the expression of genes encoding glutathione-S-transferase isoforms GSTP1-1, GSTA4-4, and GSTK1-1 during the development of the resistance of human erythroleukemia (K562), mammary adenocarcinoma (MCF-7) and ovary adenocarcinoma (SKOV-3) cells to cisplatin (CDDP). It was found that drug resistance development in all three strains of tumor cells is associated with signifi cant increase in hGSTP1 and hGSTA4 gene expression, whereas increased hGSTK1 gene expression was detected only in resistant K562/CDDP and MCF-7/CDDP cells.
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article, pubmed, google, scholar, cas, expression, cells, drug, resistance, gene, access, privacy, cookies, content, cancer, information, publish, research, search, glutathione, isoforms, tumor, cisplatin, kalinina, biol, data, log, journal, genes, gstp, gsta, gstk, berozov, shtil, open, discover, rev, download, author, russia, springer, optional, personal, parties, policy, find, track, bulletin, experimental, biology,

Topics {✒️}

month download article/chapter byulleten’ eksperimental’noi biologii hgsta4 gene expression related subjects privacy choices/manage cookies full article pdf cisplatin genetics published european economic area cdkn2a gene conditions privacy policy check access instant access drug resistance development article bulletin accepting optional cookies mcf-7/cddp cells main content log bmc evol tumor cells resistant k562/cddp journal finder publish author correspondence article log drug resistance article cite cancer ther article kalinina privacy policy personal data russian academy books a optional cookies manage preferences expression data protection drug metab essential cookies cookies skip subscription content similar content medicine aims institution subscribe journal publish usage analysis social media varying standards experimental biology resistance human erythroleukemia mammary adenocarcinoma

Schema {🗺️}

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         dateModified:2012-11-23T00:00:00Z
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            Cell Biology
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      headline:Expression of Genes of Glutathione Transferase Isoforms GSTP1-1, GSTA4-4, and GSTK1-1 in Tumor Cells during the Formation of Drug Resistance to Cisplatin
      description:We studied the expression of genes encoding glutathione-S-transferase isoforms GSTP1-1, GSTA4-4, and GSTK1-1 during the development of the resistance of human erythroleukemia (K562), mammary adenocarcinoma (MCF-7) and ovary adenocarcinoma (SKOV-3) cells to cisplatin (CDDP). It was found that drug resistance development in all three strains of tumor cells is associated with signifi cant increase in hGSTP1 and hGSTA4 gene expression, whereas increased hGSTK1 gene expression was detected only in resistant K562/CDDP and MCF-7/CDDP cells.
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         cisplatin
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         Cell Biology
         Pathology
         Laboratory Medicine
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