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Title:
The effect of external magnetic field on osteogenic and antimicrobial behaviour of surface-functionalized custom titanium chamber with iron nanoparticles. A preliminary research | Odontology
Description:
Purpose The controlled responsive characteristics of iron nanoparticles (FeNp) in magnetic fields make them an attractive prospect in this field. In the presence of a magnetic field, FeNp can significantly impact cell behaviour, leading to breakthroughs in nanotechnology. Aim/hypothesis The aim is to determine the possible applications of iron nano particles (FeNp), and induced magnetic exposure role in osteoconduction and antibacterial activity. Materials and methods The custom-grade IV titanium (Ti)hollow chamber is fabricated, surface treated with FeNp. Each titanium chamber contained neodymium, iron, and boron magnet disc, and the effect of FeNp on osteoblast-like cells (MG63) was evaluated in terms of cell attachment and survivability, morphological characteristics, particle absorption, and antibacterial properties. The effects of cellular uptake of FeNp and their responses to subcellular thrust were studied using fluorescent microscopy. MTT was used to determine cell viability, and von Kossa histochemical staining was used to determine matrix mineralization. Results In the magnetized Ti chambers group, osteogenic activity and mineralization were considerably greater than in the control groups (p 0.05). With a p value of 0.027, the S. aureus and E. coli were resistant to the antibacterial properties of the FeNp modified titanium custom Ti chamber (MIC: 0.03135 mg/mL and 0.02915 mg/mL, respectively). Conclusion The one-of-a-kind, in vitro, conveniently modelled, limited sample study sheds light on the effect of surface-functionalized titanium custom Ti chamber with FeNp on MG63. The use of magnetized FeNp-surfaced implants for long-term strategic bone tissue engineering and bacteriostatic implants.
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Keywords {🔍}
article, google, scholar, pubmed, magnetic, nanoparticles, fields, bone, iron, cells, static, osteogenic, dental, effect, field, fenp, cell, titanium, int, central, zhang, differentiation, research, res, stem, chamber, implants, wang, privacy, cookies, content, nelogi, antibacterial, activity, surface, effects, tissue, mater, kim, enhance, sci, eng, liu, chen, author, springer, information, publish, search, antimicrobial,
Topics {✒️}
magnetically-controlled ag/fe3o4 nanoparticles nano-structured iron oxide/hydroxides month download article/chapter adipose-derived stem cells custom-grade iv titanium peri-implant diseases hipsc-based tri-culture integrin-mediated cell signaling magnetized fenp-surfaced implants dental pulp cells santosh nelogi mesenchymal stem cells fe3o4 magnetic nanoparticles endosseous dental implants iron oxide nanoparticles invasive treatment static magnetic fields iron nano particles hybrid magnetic scaffolds static magnetic field ultrafine magnetic nanoparticles cu/fe3o4 nanoparticles functionalized gold nanoparticles valent iron nanoparticles full article pdf article nelogi article odontology aims privacy choices/manage cookies cell biochem biophys controlled responsive characteristics bone tissue engineering gram-positive bacteria calcium phosphate scaffold membrane-derived microvesicles human induced pluripotent external magnetic field magnetite nanoparticles effective faggion cm jr cell physiol biochem surface antigen expression magnetic nanocomposite injectables stem cells int extremely low-frequency nanomagnetic particles increase accepted manuscript version magnetic fields make dental implants pre-osteoblast cells check access underlying signaling pathways
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headline:The effect of external magnetic field on osteogenic and antimicrobial behaviour of surface-functionalized custom titanium chamber with iron nanoparticles. A preliminary research
description:The controlled responsive characteristics of iron nanoparticles (FeNp) in magnetic fields make them an attractive prospect in this field. In the presence of a magnetic field, FeNp can significantly impact cell behaviour, leading to breakthroughs in nanotechnology. The aim is to determine the possible applications of iron nano particles (FeNp), and induced magnetic exposure role in osteoconduction and antibacterial activity. The custom-grade IV titanium (Ti)hollow chamber is fabricated, surface treated with FeNp. Each titanium chamber contained neodymium, iron, and boron magnet disc, and the effect of FeNp on osteoblast-like cells (MG63) was evaluated in terms of cell attachment and survivability, morphological characteristics, particle absorption, and antibacterial properties. The effects of cellular uptake of FeNp and their responses to subcellular thrust were studied using fluorescent microscopy. MTT was used to determine cell viability, and von Kossa histochemical staining was used to determine matrix mineralization. In the magnetized Ti chambers group, osteogenic activity and mineralization were considerably greater than in the control groups (p 0.05). With a p value of 0.027, the S. aureus and E. coli were resistant to the antibacterial properties of the FeNp modified titanium custom Ti chamber (MIC: 0.03135 mg/mL and 0.02915 mg/mL, respectively). The one-of-a-kind, in vitro, conveniently modelled, limited sample study sheds light on the effect of surface-functionalized titanium custom Ti chamber with FeNp on MG63. The use of magnetized FeNp-surfaced implants for long-term strategic bone tissue engineering and bacteriostatic implants.
datePublished:2022-11-29T00:00:00Z
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Implant surface treatment
Osseointegration
Antimicrobial nanoparticles
Dental Implantation
Dentistry
Oral and Maxillofacial Surgery
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headline:The effect of external magnetic field on osteogenic and antimicrobial behaviour of surface-functionalized custom titanium chamber with iron nanoparticles. A preliminary research
description:The controlled responsive characteristics of iron nanoparticles (FeNp) in magnetic fields make them an attractive prospect in this field. In the presence of a magnetic field, FeNp can significantly impact cell behaviour, leading to breakthroughs in nanotechnology. The aim is to determine the possible applications of iron nano particles (FeNp), and induced magnetic exposure role in osteoconduction and antibacterial activity. The custom-grade IV titanium (Ti)hollow chamber is fabricated, surface treated with FeNp. Each titanium chamber contained neodymium, iron, and boron magnet disc, and the effect of FeNp on osteoblast-like cells (MG63) was evaluated in terms of cell attachment and survivability, morphological characteristics, particle absorption, and antibacterial properties. The effects of cellular uptake of FeNp and their responses to subcellular thrust were studied using fluorescent microscopy. MTT was used to determine cell viability, and von Kossa histochemical staining was used to determine matrix mineralization. In the magnetized Ti chambers group, osteogenic activity and mineralization were considerably greater than in the control groups (p 0.05). With a p value of 0.027, the S. aureus and E. coli were resistant to the antibacterial properties of the FeNp modified titanium custom Ti chamber (MIC: 0.03135 mg/mL and 0.02915 mg/mL, respectively). The one-of-a-kind, in vitro, conveniently modelled, limited sample study sheds light on the effect of surface-functionalized titanium custom Ti chamber with FeNp on MG63. The use of magnetized FeNp-surfaced implants for long-term strategic bone tissue engineering and bacteriostatic implants.
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Implant surface treatment
Osseointegration
Antimicrobial nanoparticles
Dental Implantation
Dentistry
Oral and Maxillofacial Surgery
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