We are analyzing https://link.springer.com/article/10.1007/s00535-017-1404-4.

Title:
Human hepatic stellate cell isolation and characterization | Journal of Gastroenterology
Description:
The hepatic stellate cells (HSCs) localize at the space of Disse in the liver and have multiple functions. They are identified as the major contributor to hepatic fibrosis. Significant understanding of HSCs has been achieved using rodent models and isolated murine HSCs; as well as investigating human liver tissues and human HSCs. There is growing interest and need of translating rodent study findings to human HSCs and human liver diseases. However, species-related differences impose challenges on the translational research. In this review, we focus on the current information on human HSCs isolation methods, human HSCs markers, and established human HSC cell lines.
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Keywords {🔍}

cells, human, liver, pubmed, google, scholar, article, cas, hscs, hepatic, stellate, cell, expression, hsc, normal, central, rat, fibrosis, culture, isolated, hepatology, growth, studies, isolation, livers, activated, protein, αsma, reported, desmin, factor, line, lines, droplets, receptor, primary, activation, positive, express, gfap, tissue, identified, observed, lipid, myofibroblasts, characterization, markers, fatstoring, method, fibrotic,

Topics {✒️}

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Questions {❓}

Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?
On the origin of stellate cells: mesodermal, endodermal or neuro-ectodermal?
What’s new in liver fibrosis?

Schema {🗺️}

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         headline:Human hepatic stellate cell isolation and characterization
         description:The hepatic stellate cells (HSCs) localize at the space of Disse in the liver and have multiple functions. They are identified as the major contributor to hepatic fibrosis. Significant understanding of HSCs has been achieved using rodent models and isolated murine HSCs; as well as investigating human liver tissues and human HSCs. There is growing interest and need of translating rodent study findings to human HSCs and human liver diseases. However, species-related differences impose challenges on the translational research. In this review, we focus on the current information on human HSCs isolation methods, human HSCs markers, and established human HSC cell lines.
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      headline:Human hepatic stellate cell isolation and characterization
      description:The hepatic stellate cells (HSCs) localize at the space of Disse in the liver and have multiple functions. They are identified as the major contributor to hepatic fibrosis. Significant understanding of HSCs has been achieved using rodent models and isolated murine HSCs; as well as investigating human liver tissues and human HSCs. There is growing interest and need of translating rodent study findings to human HSCs and human liver diseases. However, species-related differences impose challenges on the translational research. In this review, we focus on the current information on human HSCs isolation methods, human HSCs markers, and established human HSC cell lines.
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