We are analyzing https://link.springer.com/article/10.1007/s00415-018-8751-9.

Title:
Myasthenia gravis and infectious disease | Journal of Neurology
Description:
Background and purpose Myasthenia gravis (MG) is an autoimmune disease with muscular weakness as the only symptom, and often with immunosuppressive treatment. All these aspects could have relevance for the risk of infections as well as their prophylactic and curative treatment. Methods This is a review article, where Web of Science has been searched for relevant key words and key word combinations. Full papers were selected first by title and then by abstract. Results and conclusions MG can be triggered and worsened by infections. No virus or other pathogen has been proven to have a specific link to MG. Treatment with immunosuppressive drugs and thymectomy implies a slightly increased risk for infections. Infections should be actively treated, but a few antibiotics are avoided due to potential interference with neuromuscular transmission. Hospitalization and intensive care may be necessary during infections because of MG deterioration and risk of insufficient respiration. Vaccinations are generally recommended in MG, but live microorganisms should be avoided if possible in immunosuppressed patients.
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Keywords {🔍}

pubmed, article, google, scholar, cas, myasthenia, gravis, patients, neurol, central, infection, gilhus, disease, diseases, med, virus, study, immunol, autoimmune, infections, autoimmunity, risk, van, rev, infectious, treatment, dis, clin, vaccine, cohort, ann, epsteinbarr, privacy, cookies, content, journal, neurology, review, romi, immunosuppressive, thymectomy, access, sci, arthritis, thymus, kim, zhang, human, vaccination, publish,

Topics {✒️}

month download article/chapter epstein–barr virus infection epstein–barr virus persistence epstein–barr virus latency measles-mumps-rubella vaccination steroid-based therapy genome-wide association study bk polyomavirus-specific immunoglobulin acquired t-cell immunodeficiency anti-infectious vaccinations safe selected immune-mediated diseases nils erik gilhus systemic glucocorticoid therapy nested case–control study systemic lupus erythematosus rituximab-based immunosuppressive regimen population-based cohort study full article pdf myasthenia gravis disease thyroid autoimmune diseases privacy choices/manage cookies myasthenia gravis thymus seasonally linked diseases zika virus infection van der heijde updated consensus statement human immune system article gilhus related subjects emergency department management vaccine preventable diseases myasthenia gravis subtypes van zwet ew antibiotic-induced neurotoxicity human ganglioside gm1 infectious disease andersen jb nationwide multicenter study placebo controlled study cross-sectional study myasthenia gravis patients myasthenia gravis epidemiology myasthenia gravis treated myasthenia gravis exacerbation infectious diseases human peripheral blood van vollenhoven rf european economic area relevant key words key word combinations

Questions {❓}

Gilhus NE (2017) Eculizumab: a treatment option for mysthenia gravis?
Munz C, Lunemann JD, Getts MT, Miller SD (2009) Antiviral immune responses: triggers of or triggered by autoimmunity?
Salemi S, D’Amelio R (2010) Are anti-infectious vaccinations safe and effective in patients with autoimmunity?
Van Berkel MA, Twilla JD, England BS (2016) Emergency department management of a myasthenia gravis patient with community-acquired pneumonia: does initial antibiotic choice lead to cure or crisis?

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