We are analyzing https://link.springer.com/article/10.1007/s00415-005-0027-5.

Title:
Neuropsychological function in relation to serum parathyroid hormone and serum 25–hydroxyvitamin D levels | Journal of Neurology
Description:
There are receptors for parathyroid hormone (PTH) and 1,25–dihydroxyvitamin D in the brain, and there are clinical and experimental data indicating that PTH and vitamin D may affect cerebral function. In the present study 21 subjects who both in the 5th Tromsø study and at a follow–up examination fulfilled criteria for secondary hyperparathyroidism (SHPT) without renal failure (serum calcium < 2.40 mmol/L, serum PTH > 6.4 pmol/L, and normal serum creatinine) and 63 control subjects were compared with tests for cognitive and emotional function. Those in the SHPT group had significantly impaired performance in 3 of 14 cognitive tests (Digit span forward, Stroop test part 1 and 2, and Word association test (FAS)) as compared with the controls, and also had a significantly higher depression score at the Beck Depression Inventory (BDI) (items 1–13). In a multiple linear regression model, a high serum PTH level was significantly associated with low performance at the Digit span forward, Stroop test part 1 and 2, and Digit Symbol tests. A low level of serum 25–hydroxyvitamin D was significantly associated with a high depression score. In conclusion, a deranged calcium metabolism appears to be associated with impaired function in several tests of neuropsychological function.
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google, scholar, article, cas, pubmed, parathyroid, hormone, serum, function, vitamin, tromsø, study, hyperparathyroidism, calcium, jorde, test, privacy, cookies, content, journal, neuropsychological, pth, subjects, tests, cognitive, depression, access, endocrinol, metab, receptor, university, norway, data, publish, search, hydroxyvitamin, brain, clinical, significantly, primary, health, wechsler, medicine, information, log, research, neurology, november, waterloo, saleh,

Topics {✒️}

month download article/chapter parathyroid hormone–related peptide wechsler memory scale–revised beck depression inventory blood–brain barrier function pth/pthrp receptor mrna full article pdf high depression score privacy choices/manage cookies general health questionnaire serum parathyroid hormone emotional function sporadic primary hyperparathyroidism affect cerebral function metabolic syndrome protein–linked receptor european economic area scope submit manuscript examination fulfilled criteria digit span forward population based study abou–samra ab kolakowski lf jr potts jt jr kähönen–väre mh normal serum creatinine 5th tromsø study mice lacking vitamin related subjects experimental data indicating conditions privacy policy central nervous dysfunction calcium metabolism brain target sites pth–induced rise serum ionised calcium central nervous system accepting optional cookies aker university hospital parathyroid hormone article journal word association test digit symbol tests journal finder publish cognitive function article log bønaa kh article jorde significantly impaired performance health screening

Schema {🗺️}

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         headline:Neuropsychological function in relation to serum parathyroid hormone and serum 25–hydroxyvitamin D levels
         description:There are receptors for parathyroid hormone (PTH) and 1,25–dihydroxyvitamin D in the brain, and there are clinical and experimental data indicating that PTH and vitamin D may affect cerebral function. In the present study 21 subjects who both in the 5th Tromsø study and at a follow–up examination fulfilled criteria for secondary hyperparathyroidism (SHPT) without renal failure (serum calcium < 2.40 mmol/L, serum PTH > 6.4 pmol/L, and normal serum creatinine) and 63 control subjects were compared with tests for cognitive and emotional function. Those in the SHPT group had significantly impaired performance in 3 of 14 cognitive tests (Digit span forward, Stroop test part 1 and 2, and Word association test (FAS)) as compared with the controls, and also had a significantly higher depression score at the Beck Depression Inventory (BDI) (items 1–13). In a multiple linear regression model, a high serum PTH level was significantly associated with low performance at the Digit span forward, Stroop test part 1 and 2, and Digit Symbol tests. A low level of serum 25–hydroxyvitamin D was significantly associated with a high depression score. In conclusion, a deranged calcium metabolism appears to be associated with impaired function in several tests of neuropsychological function.
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      headline:Neuropsychological function in relation to serum parathyroid hormone and serum 25–hydroxyvitamin D levels
      description:There are receptors for parathyroid hormone (PTH) and 1,25–dihydroxyvitamin D in the brain, and there are clinical and experimental data indicating that PTH and vitamin D may affect cerebral function. In the present study 21 subjects who both in the 5th Tromsø study and at a follow–up examination fulfilled criteria for secondary hyperparathyroidism (SHPT) without renal failure (serum calcium < 2.40 mmol/L, serum PTH > 6.4 pmol/L, and normal serum creatinine) and 63 control subjects were compared with tests for cognitive and emotional function. Those in the SHPT group had significantly impaired performance in 3 of 14 cognitive tests (Digit span forward, Stroop test part 1 and 2, and Word association test (FAS)) as compared with the controls, and also had a significantly higher depression score at the Beck Depression Inventory (BDI) (items 1–13). In a multiple linear regression model, a high serum PTH level was significantly associated with low performance at the Digit span forward, Stroop test part 1 and 2, and Digit Symbol tests. A low level of serum 25–hydroxyvitamin D was significantly associated with a high depression score. In conclusion, a deranged calcium metabolism appears to be associated with impaired function in several tests of neuropsychological function.
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         depression
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         parathyroid hormone
         vitamin D
         Neurology
         Neurosciences
         Neuroradiology
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