We are analyzing https://link.springer.com/article/10.1007/s00412-009-0240-6.

Title:
Solving the Dnmt2 enigma | Chromosoma
Description:
Dnmt2 is a member of the animal DNA methyltransferase family of enzymes. While the role of other Dnmt proteins has been extensively characterized, comparably little is known about Dnmt2. This is surprising because Dnmt2 is the most widely conserved Dnmt protein, with homologues in protists, plants, fungi, and animals. In this review, we discuss the evidence supporting the seemingly contradictory roles of Dnmt2 in both DNA and RNA methylation. New studies are uncovering the enzymatic mechanisms that mediate these activities and also provide first insights into the biological functions of Dnmt2. Lastly, we also discuss observations that suggest a possible role for Dnmt2 in human health and disease, which further emphasizes the importance of defining Dnmt2-modulated cellular pathways in future studies.
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Keywords {🔍}

article, pubmed, google, scholar, cas, dna, dnmt, methyltransferase, lyko, methylation, cytosine, nucleic, acids, res, schaefer, rna, bestor, drosophila, privacy, cookies, content, human, access, mol, biochem, analysis, information, publish, research, search, frank, protein, mammalian, methyltransferases, trna, cell, biol, yoder, cancer, genes, gene, data, log, journal, chromosoma, family, related, discover, epigenetics, chem,

Topics {✒️}

post-transcriptional nucleotide modification month download article/chapter maintenance-type dna methyltransferase displays denaturant-resistant binding replication-independent chromatin loading scaffold/matrix attachment region bisulfite sequencing methyltransferase activity article chromosoma aims full article pdf site-specific analysis nuclear matrix protein article schaefer privacy choices/manage cookies 5-cytosine dna methyltransferase dna methyltransferase homologue dna methyltransferase family related subjects dnmt2 target sites dna methylation post-mitotic neurons mammalian germ cells access dna european economic area seemingly contradictory roles cytosine methylated regions genomic imprinting disrupted maternal effect mutation epigenetic control single amino acid eukaryotic cytosine methyltransferases conditions privacy policy frank lyko dna methyltransferase rapid trna decay accepting optional cookies rna methylation article log mammalian dna press schaefer main content log usage analysis dnmt1 gene dnmt2 enigma journal finder publish article cite check access instant access fission yeast enzymes

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         general
         Human Genetics
         Animal Genetics and Genomics
         Eukaryotic Microbiology
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