LINK . SPRINGER . COM {}

Matching Content Categories {📚}

• Education
• Science
• Politics

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,016 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don’t know how the website earns money.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Link.springer.com might be cashing in, but we can't detect the method they're using.

Keywords {🔍}

article, paulo, inflammasome, severe, atopic, dermatitis, ilβ, nlrp, sao, asc, gsdmd, research, orfali, caspase, expression, study, pubmed, author, privacy, cookies, aoki, raquel, leão, skin, moderate, dermatology, brazil, supplementary, material, content, analysis, data, information, publish, search, gasdermind, macrophages, sato, aim, epidermis, dermis, access, cas, google, scholar, são, springer, log, journal, cutaneous,

Topics {✒️}

mírian nacagami sotto month download article/chapter raquel leão orfali joyce tiyeko kawakami dermatological research aims electronic supplementary material il-1β-secreting macrophages severe atopic dermatitis privacy choices/manage cookies full article pdf inflammatory skin disease chronic skin colonization atopic dermatitis sao paulo school inflammasome components nlrp1 inflammasome complex evidenced sao paulo-sp article ramos european economic area potential disease biomarkers key transcription factor promising therapeutic approach additional information publisher conditions privacy policy disease inflammatory mechanisms detected positive correlation cutaneous macrophages naiura vieira pereira ethics declarations conflict il-1β expression sato mn accepting optional cookies article archives macrophage marker staphylococcus aureus enterotoxins author correspondence personal data ethics statement inflammasome complex inflammasome pathway journal finder publish canonical activation pathway article log data protection check access instant access article number 156 gasdermin pores sao paulo são paulo

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Cutaneous inflammasome driving ASC / gasdermin-D activation and IL-1β-secreting macrophages in severe atopic dermatitis
         description: Atopic dermatitis (AD) is an inflammatory skin disease with intense pruritus, and chronic skin colonization by Staphylococcus aureus. To understand the inflammatory status in AD, we investigated the inflammasome complex, that activates ASC (Apoptosis-associated speck-like protein containing a CARD), caspase-1 and GSDMD (gasdermin-D), and production of IL-1β and IL-18. We aimed to evaluate the expression of the inflammasome pathway in the skin of adults with AD. Thirty patients with moderate to severe AD and 20 healthy controls were enrolled in the study. We performed the analysis of the inflammasome components NLRP1, NLRP3, AIM-2, IL-1β, IL-18, Caspase-1, ASC, GSDMD, and CD68 expression (macrophage marker) by immunohistochemistry and immunofluorescence. The main findings included increased expression of NLRP3, NLRP1 and AIM-2 at dermal level of severe AD; augmented IL-18 and IL-1β expression at epidermis of moderate and severe patients, and in the dermis of severe AD; augmented expression of ASC, caspase-1 and GSDMD in both epidermis and dermis of moderate and severe AD. We detected positive correlation between caspase-1, GSDMD and IL-1β (epidermis) and caspase-1 (dermis) and AD severity; NLRP3, AIM-2 and IL-1β, and NLRP3 with IL-18 in the epidermis; ASC, GSDMD and IL-1β, and NLRP3, AIM-2, caspase-1, and IL-18 in the dermis. We also evidenced the presence of CD68+ macrophages secreting GSDMD, ASC and IL-1β in moderate and severe AD. Cutaneous macrophages, early detected in moderate AD, have its role in the disease inflammatory mechanisms. Our study indicates a canonical activation pathway of inflammasomes, reinforced by the chronic status of inflammation in AD. The analysis of the inflammasome complex evidenced an imbalance in its regulation, with increased expression of the evaluated components, which is remarkably in severe AD, emphasizing its relevance as potential disease biomarkers and targets for immunomodulatory interventions.
         datePublished:2024-05-11T00:00:00Z
         dateModified:2024-05-11T00:00:00Z
         pageStart:1
         pageEnd:5
         sameAs:https://doi.org/10.1007/s00403-024-02899-0
         keywords:
            Atopic dermatitis
            Inflammasome
            Keratinocytes
            Macrophage
            IL-1β
            gasdermin-D
            Dermatology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_Fig2_HTML.png
         isPartOf:
            name:Archives of Dermatological Research
            issn:
               1432-069X
            volumeNumber:316
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Berlin Heidelberg
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Yasmim Álefe Leuzzi Ramos
               url:http://orcid.org/0009-0005-7185-4569
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Naiura Vieira Pereira
               url:http://orcid.org/0000-0003-4157-8127
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Valeria Aoki
               url:http://orcid.org/0000-0003-4256-4413
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mírian Nacagami Sotto
               url:http://orcid.org/0000-0001-6380-7192
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Joyce Tiyeko Kawakami
               url:http://orcid.org/0009-0007-2366-1740
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Laboratory of Heart Pathology, Heart Institute (InCor), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Luiz Fernando Ferraz da Silva
               url:http://orcid.org/0000-0002-0181-6357
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Maria Notomi Sato
               url:http://orcid.org/0000-0002-7911-1824
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Raquel Leão Orfali
               url:http://orcid.org/0000-0002-2807-1404
               affiliation:
                     name:Universidade de Sao Paulo
                     address:
                        name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Cutaneous inflammasome driving ASC / gasdermin-D activation and IL-1β-secreting macrophages in severe atopic dermatitis
      description: Atopic dermatitis (AD) is an inflammatory skin disease with intense pruritus, and chronic skin colonization by Staphylococcus aureus. To understand the inflammatory status in AD, we investigated the inflammasome complex, that activates ASC (Apoptosis-associated speck-like protein containing a CARD), caspase-1 and GSDMD (gasdermin-D), and production of IL-1β and IL-18. We aimed to evaluate the expression of the inflammasome pathway in the skin of adults with AD. Thirty patients with moderate to severe AD and 20 healthy controls were enrolled in the study. We performed the analysis of the inflammasome components NLRP1, NLRP3, AIM-2, IL-1β, IL-18, Caspase-1, ASC, GSDMD, and CD68 expression (macrophage marker) by immunohistochemistry and immunofluorescence. The main findings included increased expression of NLRP3, NLRP1 and AIM-2 at dermal level of severe AD; augmented IL-18 and IL-1β expression at epidermis of moderate and severe patients, and in the dermis of severe AD; augmented expression of ASC, caspase-1 and GSDMD in both epidermis and dermis of moderate and severe AD. We detected positive correlation between caspase-1, GSDMD and IL-1β (epidermis) and caspase-1 (dermis) and AD severity; NLRP3, AIM-2 and IL-1β, and NLRP3 with IL-18 in the epidermis; ASC, GSDMD and IL-1β, and NLRP3, AIM-2, caspase-1, and IL-18 in the dermis. We also evidenced the presence of CD68+ macrophages secreting GSDMD, ASC and IL-1β in moderate and severe AD. Cutaneous macrophages, early detected in moderate AD, have its role in the disease inflammatory mechanisms. Our study indicates a canonical activation pathway of inflammasomes, reinforced by the chronic status of inflammation in AD. The analysis of the inflammasome complex evidenced an imbalance in its regulation, with increased expression of the evaluated components, which is remarkably in severe AD, emphasizing its relevance as potential disease biomarkers and targets for immunomodulatory interventions.
      datePublished:2024-05-11T00:00:00Z
      dateModified:2024-05-11T00:00:00Z
      pageStart:1
      pageEnd:5
      sameAs:https://doi.org/10.1007/s00403-024-02899-0
      keywords:
         Atopic dermatitis
         Inflammasome
         Keratinocytes
         Macrophage
         IL-1β
         gasdermin-D
         Dermatology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_Fig2_HTML.png
      isPartOf:
         name:Archives of Dermatological Research
         issn:
            1432-069X
         volumeNumber:316
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Yasmim Álefe Leuzzi Ramos
            url:http://orcid.org/0009-0005-7185-4569
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Naiura Vieira Pereira
            url:http://orcid.org/0000-0003-4157-8127
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Valeria Aoki
            url:http://orcid.org/0000-0003-4256-4413
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mírian Nacagami Sotto
            url:http://orcid.org/0000-0001-6380-7192
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Joyce Tiyeko Kawakami
            url:http://orcid.org/0009-0007-2366-1740
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Laboratory of Heart Pathology, Heart Institute (InCor), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Luiz Fernando Ferraz da Silva
            url:http://orcid.org/0000-0002-0181-6357
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maria Notomi Sato
            url:http://orcid.org/0000-0002-7911-1824
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Raquel Leão Orfali
            url:http://orcid.org/0000-0002-2807-1404
            affiliation:
                  name:Universidade de Sao Paulo
                  address:
                     name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Archives of Dermatological Research
      issn:
         1432-069X
      volumeNumber:316
Organization:
      name:Springer Berlin Heidelberg
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Universidade de Sao Paulo
      address:
         name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Laboratory of Heart Pathology, Heart Institute (InCor), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
         type:PostalAddress
      name:Universidade de Sao Paulo
      address:
         name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Yasmim Álefe Leuzzi Ramos
      url:http://orcid.org/0009-0005-7185-4569
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
               type:PostalAddress
            type:Organization
      name:Naiura Vieira Pereira
      url:http://orcid.org/0000-0003-4157-8127
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
               type:PostalAddress
            type:Organization
      name:Valeria Aoki
      url:http://orcid.org/0000-0003-4256-4413
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
               type:PostalAddress
            type:Organization
      name:Mírian Nacagami Sotto
      url:http://orcid.org/0000-0001-6380-7192
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
               type:PostalAddress
            type:Organization
      name:Joyce Tiyeko Kawakami
      url:http://orcid.org/0009-0007-2366-1740
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Laboratory of Heart Pathology, Heart Institute (InCor), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
               type:PostalAddress
            type:Organization
      name:Luiz Fernando Ferraz da Silva
      url:http://orcid.org/0000-0002-0181-6357
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
               type:PostalAddress
            type:Organization
      name:Maria Notomi Sato
      url:http://orcid.org/0000-0002-7911-1824
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
               type:PostalAddress
            type:Organization
      name:Raquel Leão Orfali
      url:http://orcid.org/0000-0002-2807-1404
      affiliation:
            name:Universidade de Sao Paulo
            address:
               name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
      name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
      name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
      name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
      name:Laboratory of Heart Pathology, Heart Institute (InCor), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
      name:Department of Pathology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
      name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
      name:Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sala, Sao Paulo-SP, Cerqueira Cesar, Brazil
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(71)

• https://www.springernature.com/gp/authors's revenue stream
• How much does https://link.springernature.com/home/ gross monthly?
• What's the monthly income of https://order.springer.com/public/cart?
• Discover the revenue of https://submission.nature.com/new-submission/403/3
• How much does https://orcid.org/0009-0005-7185-4569 generate monthly?
• How much does https://orcid.org/0000-0003-4157-8127 earn?
• How much money does https://orcid.org/0000-0003-4256-4413 generate?
• Find out how much https://orcid.org/0000-0001-6380-7192 earns monthly
• https://orcid.org/0009-0007-2366-1740's total income per month
• How much does https://orcid.org/0000-0002-0181-6357 earn?
• What is the monthly revenue of https://orcid.org/0000-0002-7911-1824?
• See how much https://orcid.org/0000-0002-2807-1404 makes per month
• What is the monthly revenue of https://www.springernature.com/gp/librarians/licensing/agc/journals?
• Financial intake of https://doi.org/10.1101/cshperspect.a036392
• Find out how much https://doi.org/10.1111/j.1600-0625.2009.00842.x earns monthly
• How much does https://doi.org/10.1111%2Fj.1600-0625.2009.00842.x bring in each month?
• What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19469892's gross income?
• How much income does http://scholar.google.com/scholar_lookup?&title=Atopic%20dermatitis%20in%20adults%3A%20evaluation%20of%20peripheral%20blood%20mononuclear%20cells%20proliferation%20response%20to%20Staphylococcus%20aureus%20enterotoxins%20a%20and%20B%20and%20analysis%20of%20interleukin-18%20secretion&journal=Exp%20Dermatol&doi=10.1111%2Fj.1600-0625.2009.00842.x&volume=18&issue=7&pages=628-633&publication_year=2009&author=Orfali%2CRL&author=Sato%2CMN&author=Takaoka%2CR&author=Azor%2CMH&author=Rivitti%2CEA&author=Hanifin%2CJM&author=Aoki%2CV have?
• How much does https://doi.org/10.1038/s41419-021-04159-9 net monthly?
• How much does https://doi.org/10.1038%2Fs41419-021-04159-9 make?
• Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=34561424 is on a monthly basis
• Learn how profitable http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463682 is on a monthly basis
• Revenue of http://scholar.google.com/scholar_lookup?&title=A%20novel%20function%20of%20NLRP3%20independent%20of%20inflammasome%20as%20a%20key%20transcription%20factor%20of%20IL-33%20in%20epithelial%20cells%20of%20atopic%20dermatitis&journal=Cell%20Death%20Dis&doi=10.1038%2Fs41419-021-04159-9&volume=12&issue=10&publication_year=2021&author=Zheng%2CJ&author=Yao%2CL&author=Zhou%2CY&author=Gu%2CX&author=Wang%2CC&author=Bao%2CK
• Earnings of https://doi.org/10.3389/fimmu.2020.00882
• What are the total earnings of https://doi.org/10.3389%2Ffimmu.2020.00882?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=32528469 pull in monthly?
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247819 gross monthly?
• http://scholar.google.com/scholar_lookup?&title=Inflammasomes%20in%20Common%20Immune-related%20skin%20diseases&journal=Front%20Immunol&doi=10.3389%2Ffimmu.2020.00882&volume=11&publication_year=2020&author=Tang%2CL&author=Zhou%2CF income
• Get to know https://doi.org/10.1016/j.intimp.2023.110958's earnings
• Get to know https://doi.org/10.1016%2Fj.intimp.2023.110958's earnings
• What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=37741129?
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20gasdermin%20D%20%28GSDMD%29%20as%20a%20promising%20therapeutic%20approach%20for%20atopic%20dermatitis&journal=Int%20Immunopharmacol&doi=10.1016%2Fj.intimp.2023.110958&volume=124&issue=Pt%20B&publication_year=2023&author=Lu%2CY&author=Sun%2CY&author=Peng%2CY&author=Zhao%2CX&author=Wang%2CD&author=Zhang%2CT?
• See how much https://citation-needed.springer.com/v2/references/10.1007/s00403-024-02899-0?format=refman&flavour=references makes per month
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yasmim%20%C3%81lefe%20Leuzzi%20Ramos income
• Learn about the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yasmim%20%C3%81lefe%20Leuzzi%20Ramos%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Naiura%20Vieira%20Pereira
• Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Naiura%20Vieira%20Pereira%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Valeria%20Aoki earns monthly
• Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Valeria%20Aoki%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=M%C3%ADrian%20Nacagami%20Sotto's financial summary
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22M%C3%ADrian%20Nacagami%20Sotto%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Joyce%20Tiyeko%20Kawakami bring in?
• How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Joyce%20Tiyeko%20Kawakami%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
• Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Luiz%20Fernando%20Ferraz%20da%20Silva
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Luiz%20Fernando%20Ferraz%20da%20Silva%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Maria%20Notomi%20Sato generate?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Maria%20Notomi%20Sato%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
• How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Raquel%20Le%C3%A3o%20Orfali earning monthly?
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Raquel%20Le%C3%A3o%20Orfali%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• How much does https://static-content.springer.com/esm/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_MOESM1_ESM.pdf earn?
• See how much https://static-content.springer.com/esm/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_MOESM2_ESM.pdf makes per month
• How much does https://static-content.springer.com/esm/art%3A10.1007%2Fs00403-024-02899-0/MediaObjects/403_2024_2899_MOESM3_ESM.pdf pull in monthly?
• Monthly income for https://s100.copyright.com/AppDispatchServlet?title=Cutaneous%20inflammasome%20driving%20ASC%20%2F%20gasdermin-D%20activation%20and%20IL-1%CE%B2-secreting%20macrophages%20in%20severe%20atopic%20dermatitis&author=Yasmim%20%C3%81lefe%20Leuzzi%20Ramos%20et%20al&contentID=10.1007%2Fs00403-024-02899-0©right=The%20Author%28s%29%2C%20under%20exclusive%20licence%20to%20Springer-Verlag%20GmbH%20Germany%2C%20part%20of%20Springer%20Nature&publication=1432-069X&publicationDate=2024-05-11&publisherName=SpringerNature&orderBeanReset=true
• https://crossmark.crossref.org/dialog/?doi=10.1007/s00403-024-02899-0's revenue stream
• https://citation-needed.springer.com/v2/references/10.1007/s00403-024-02899-0?format=refman&flavour=citation's total income per month
• What are the earnings of https://authorservices.springernature.com/go/sn/?utm_source=SNLinkfooter&utm_medium=Web&utm_campaign=SNReferral?
• https://www.springernature.com/gp/open-research/about/the-fundamentals-of-open-access-and-open-research's total income per month
• How much does https://www.springernature.com/gp/products earn?
• What's the financial outcome of https://www.springernature.com/gp/librarians?
• How much money does https://www.springernature.com/gp/societies make?
• What's the income generated by https://www.springernature.com/gp/partners each month?
• How much income is https://www.springer.com/ earning monthly?
• How much profit does https://www.nature.com/ generate?
• What's https://www.biomedcentral.com/'s gross income?
• How much profit does https://www.palgrave.com/ generate?
• How much does https://www.apress.com/ rake in every month?
• How much does https://www.springernature.com/gp/legal/ccpa net monthly?
• Discover the revenue of https://www.springernature.com/gp/info/accessibility
• What's the monthly income of https://support.springernature.com/en/support/home?
• What's https://support.springernature.com/en/support/solutions/articles/6000255911-subscription-cancellations's gross income?
• https://www.springernature.com/'s revenue stream

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Clipboard.js
• Prism.js

CDN Services {📦}

• Crossref