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Questions {❓}

• Giannitsis E, Katus HA (2015) A long way to translation: will cMyC survive?
• Heusch G (2015) CIRCUS: a kiss of death for cardioprotection?
• Heusch G, Gersh BJ (2015) ERICCA and RIPHeart: two nails in the coffin for cardioprotection by remote ischemic conditioning?
• Is ischemia the only factor predicting cardiovascular outcomes in all diabetes mellitus patients?

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         headline:Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside
         description:Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last “New Frontiers in Cardiovascular Research meeting”. Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemia–reperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.
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      headline:Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside
      description:Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last “New Frontiers in Cardiovascular Research meeting”. Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemia–reperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.
      datePublished:2015-12-14T00:00:00Z
      dateModified:2015-12-14T00:00:00Z
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      license:http://creativecommons.org/licenses/by/4.0/
      sameAs:https://doi.org/10.1007/s00395-015-0527-0
      keywords:
         Atherosclerosis
         Cardioprotection
         Cardiovascular disease
         Endothelial permeability
         Extracellular RNA
         High-density lipoprotein
         Hypoxia
         Inflammation
         Ischemia/reperfusion injury
         Macrophage polarization
         MicroRNAs
         Mitochondria
         Platelet dysfunction
         Vascular biology
         Cardiology
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