We are analyzing https://link.springer.com/article/10.1007/s00384-012-1587-3.

Title:
Enteral nutrition to suppress postoperative Crohn’s disease recurrence: a five-year prospective cohort study | International Journal of Colorectal Disease
Description:
The aim of this study was to investigate the long-term effect of enteral nutrition (EN) as a maintenance therapy in Crohn’s disease (CD) patients following surgery. This study was an extension of our previous study to prolong the duration of intervention and follow-up from 1 to 5 years. Forty consecutive patients who underwent resection for ileal or ileocolic CD were included. Following surgery, 20 patients received continuous elemental diet infusion during the nighttime plus a low-fat diet during the daytime (EN group). Another 20 patients received neither nutritional therapy nor food restriction (control group). All patients were followed for 5 years after operation. No patient received corticosteroid, immunosuppressants, or infliximab except patients who developed recurrence. The end point of this study was recurrence requiring biologic therapy or reoperation. Recurrence rates were analyzed on an intention-to-treat basis. In the EN group, four patients could not continue tube intubation for elemental diet intake. Two patients (10 %) in the EN group and nine patients (45 %) in the control group developed recurrence requiring infliximab therapy (P = 0.03). The cumulative recurrence incidence rate requiring infliximab was significantly lower in the EN group vs the control group (P = 0.02). One patient (5 %) in the EN group and five patients (25 %) in the control group required reoperation for recurrence (P = 0.18). The cumulative incidence of reoperation was lower in the EN group vs the control group, the difference not being significant (P = 0.08). The outcomes of this study suggest that EN therapy reduces the incidence of postoperative CD recurrence.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Science
Fitness & Wellness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,642,828 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure how the site profits.

Many websites are intended to earn money, but some serve to share ideas or build connections. Websites exist for all kinds of purposes. This might be one of them. Link.springer.com might be cashing in, but we can't detect the method they're using.

Keywords {🔍}

disease, article, crohns, enteral, pubmed, google, scholar, nutrition, recurrence, cas, therapy, patients, group, study, yamamoto, nutritional, postoperative, nakahigashi, diet, matsumoto, bowel, privacy, cookies, content, journal, prospective, umegae, surgery, control, infliximab, remission, dis, gastroenterol, publish, search, colorectal, maintenance, elemental, reoperation, access, inflammatory, treatment, griffiths, gastroenterology, data, information, log, research, september, takayuki,

Topics {✒️}

satoru umegae & koichi matsumoto month download article/chapter inflammatory bowel disease—epidemiology long-term enteral nutrition inflammatory bowel disease article international journal full article pdf privacy choices/manage cookies related subjects review article parenteral nutrition therapy long-term effect enteral nutritional therapy elemental diet intake �half elemental diet article yamamoto factors affecting recurrence post-operative recurrence continue tube intubation protein-energy intake intra-operative enteroscopy low-fat diet colorectal disease aims en therapy reduces conditions privacy policy patient received corticosteroid oral nutritional supplementation disease activity index european economic area journal finder publish accepting optional cookies prospective clinical trial endoscopic disease activities author information authors developed recurrence forty consecutive patients national cooperative crohn takayuki yamamoto randomized-controlled trial postoperative cd recurrence article log enteral nutrition cumulative incidence suppress postoperative crohn check access bowel resection instant access article cite elemental diet maintenance infliximab

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Enteral nutrition to suppress postoperative Crohn’s disease recurrence: a five-year prospective cohort study
         description:The aim of this study was to investigate the long-term effect of enteral nutrition (EN) as a maintenance therapy in Crohn’s disease (CD) patients following surgery. This study was an extension of our previous study to prolong the duration of intervention and follow-up from 1 to 5 years. Forty consecutive patients who underwent resection for ileal or ileocolic CD were included. Following surgery, 20 patients received continuous elemental diet infusion during the nighttime plus a low-fat diet during the daytime (EN group). Another 20 patients received neither nutritional therapy nor food restriction (control group). All patients were followed for 5 years after operation. No patient received corticosteroid, immunosuppressants, or infliximab except patients who developed recurrence. The end point of this study was recurrence requiring biologic therapy or reoperation. Recurrence rates were analyzed on an intention-to-treat basis. In the EN group, four patients could not continue tube intubation for elemental diet intake. Two patients (10 %) in the EN group and nine patients (45 %) in the control group developed recurrence requiring infliximab therapy (P = 0.03). The cumulative recurrence incidence rate requiring infliximab was significantly lower in the EN group vs the control group (P = 0.02). One patient (5 %) in the EN group and five patients (25 %) in the control group required reoperation for recurrence (P = 0.18). The cumulative incidence of reoperation was lower in the EN group vs the control group, the difference not being significant (P = 0.08). The outcomes of this study suggest that EN therapy reduces the incidence of postoperative CD recurrence.
         datePublished:2012-09-27T00:00:00Z
         dateModified:2012-09-27T00:00:00Z
         pageStart:335
         pageEnd:340
         sameAs:https://doi.org/10.1007/s00384-012-1587-3
         keywords:
            Crohn’s disease
            Enteral nutrition
            Infliximab
            Recurrence
            Reoperation
            Surgery
            Internal Medicine
            Gastroenterology
            Hepatology
            Proctology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00384-012-1587-3/MediaObjects/384_2012_1587_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00384-012-1587-3/MediaObjects/384_2012_1587_Fig2_HTML.gif
         isPartOf:
            name:International Journal of Colorectal Disease
            issn:
               1432-1262
               0179-1958
            volumeNumber:28
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Takayuki Yamamoto
               affiliation:
                     name:Yokkaichi Social Insurance Hospital
                     address:
                        name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Manabu Shiraki
               affiliation:
                     name:Yokkaichi Social Insurance Hospital
                     address:
                        name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Maki Nakahigashi
               affiliation:
                     name:Yokkaichi Social Insurance Hospital
                     address:
                        name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Satoru Umegae
               affiliation:
                     name:Yokkaichi Social Insurance Hospital
                     address:
                        name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Koichi Matsumoto
               affiliation:
                     name:Yokkaichi Social Insurance Hospital
                     address:
                        name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Enteral nutrition to suppress postoperative Crohn’s disease recurrence: a five-year prospective cohort study
      description:The aim of this study was to investigate the long-term effect of enteral nutrition (EN) as a maintenance therapy in Crohn’s disease (CD) patients following surgery. This study was an extension of our previous study to prolong the duration of intervention and follow-up from 1 to 5 years. Forty consecutive patients who underwent resection for ileal or ileocolic CD were included. Following surgery, 20 patients received continuous elemental diet infusion during the nighttime plus a low-fat diet during the daytime (EN group). Another 20 patients received neither nutritional therapy nor food restriction (control group). All patients were followed for 5 years after operation. No patient received corticosteroid, immunosuppressants, or infliximab except patients who developed recurrence. The end point of this study was recurrence requiring biologic therapy or reoperation. Recurrence rates were analyzed on an intention-to-treat basis. In the EN group, four patients could not continue tube intubation for elemental diet intake. Two patients (10 %) in the EN group and nine patients (45 %) in the control group developed recurrence requiring infliximab therapy (P = 0.03). The cumulative recurrence incidence rate requiring infliximab was significantly lower in the EN group vs the control group (P = 0.02). One patient (5 %) in the EN group and five patients (25 %) in the control group required reoperation for recurrence (P = 0.18). The cumulative incidence of reoperation was lower in the EN group vs the control group, the difference not being significant (P = 0.08). The outcomes of this study suggest that EN therapy reduces the incidence of postoperative CD recurrence.
      datePublished:2012-09-27T00:00:00Z
      dateModified:2012-09-27T00:00:00Z
      pageStart:335
      pageEnd:340
      sameAs:https://doi.org/10.1007/s00384-012-1587-3
      keywords:
         Crohn’s disease
         Enteral nutrition
         Infliximab
         Recurrence
         Reoperation
         Surgery
         Internal Medicine
         Gastroenterology
         Hepatology
         Proctology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00384-012-1587-3/MediaObjects/384_2012_1587_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00384-012-1587-3/MediaObjects/384_2012_1587_Fig2_HTML.gif
      isPartOf:
         name:International Journal of Colorectal Disease
         issn:
            1432-1262
            0179-1958
         volumeNumber:28
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Takayuki Yamamoto
            affiliation:
                  name:Yokkaichi Social Insurance Hospital
                  address:
                     name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Manabu Shiraki
            affiliation:
                  name:Yokkaichi Social Insurance Hospital
                  address:
                     name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maki Nakahigashi
            affiliation:
                  name:Yokkaichi Social Insurance Hospital
                  address:
                     name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Satoru Umegae
            affiliation:
                  name:Yokkaichi Social Insurance Hospital
                  address:
                     name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Koichi Matsumoto
            affiliation:
                  name:Yokkaichi Social Insurance Hospital
                  address:
                     name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:International Journal of Colorectal Disease
      issn:
         1432-1262
         0179-1958
      volumeNumber:28
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Yokkaichi Social Insurance Hospital
      address:
         name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
         type:PostalAddress
      name:Yokkaichi Social Insurance Hospital
      address:
         name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
         type:PostalAddress
      name:Yokkaichi Social Insurance Hospital
      address:
         name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
         type:PostalAddress
      name:Yokkaichi Social Insurance Hospital
      address:
         name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
         type:PostalAddress
      name:Yokkaichi Social Insurance Hospital
      address:
         name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Takayuki Yamamoto
      affiliation:
            name:Yokkaichi Social Insurance Hospital
            address:
               name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Manabu Shiraki
      affiliation:
            name:Yokkaichi Social Insurance Hospital
            address:
               name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
               type:PostalAddress
            type:Organization
      name:Maki Nakahigashi
      affiliation:
            name:Yokkaichi Social Insurance Hospital
            address:
               name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
               type:PostalAddress
            type:Organization
      name:Satoru Umegae
      affiliation:
            name:Yokkaichi Social Insurance Hospital
            address:
               name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
               type:PostalAddress
            type:Organization
      name:Koichi Matsumoto
      affiliation:
            name:Yokkaichi Social Insurance Hospital
            address:
               name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
      name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
      name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
      name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
      name:Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Japan
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(87)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

3.41s.

LINK . SPRINGER . COM {}