We are analyzing https://link.springer.com/article/10.1007/s00217-020-03449-4.

Title:
The impact of l-lanthionine supplementation on the production of nisin by lactococci | European Food Research and Technology
Description:
The combination of cost-effective synthesis of l-lanthionine in conjunction with a fermentation process could be considered as an original approach. Innovative biosynthesis of nisin is easy to scale-up. After the selective organic synthesis of the thioether building block, cultivation medium M17 broth with glucose (0.5% w/w) was supplemented with l-lanthionine (0.78, 3.91 and 7.82 mg ml−1) to stimulate nisin biosynthesis by lactococci. The viability of nisin-producing Lactococcus lactis subsp. lactis strains (CCDM 731, NIZO R5, LTM 32, CCDM 416) and nisin production were evaluated. Nisin synthesis was significantly influenced by l-lanthionine supplementation and it increased for all the strains tested in comparison with a control. The most significant increase in nisin concentration was observed for strains CCDM 731 and LTM 32, where up to 88.6% and 90.0%, respectively, were achieved. The influence of l-lanthionine concentration was shown to be strain specific.
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Keywords {🔍}

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Topics {✒️}

monika kumherová & jan kyselka month download article/chapter jan kyselka ser/thr dehydration catalysed high-resolution ms measurements šárka horáčková view author information authors biopreservative bacteriocins lactococcus lactis subsp protected lanthionine synthesis author correspondence cost-effective synthesis chemical synthesis versus l-lanthionine supplementation selective organic synthesis privacy choices/manage cookies l-lanthionine concentration european economic area full article pdf stimulate nisin biosynthesis check access ii lantibiotics specific university research instant access nisin synthesis low cost production thioether building block nonproteinogenic amino acids michael-type cyclizations mass spectral properties agar diffusion bioassay factor “indicator microorganism” response surface methodology l-lanthionine conditions privacy policy electronic supplementary material accepting optional cookies lantibiotics additional information publisher' stereoselective synthesis article feldeková ethics declarations conflict journal finder publish lactis strains lactis nizo 22186 nisin production horáčková article log technology article

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