We are analyzing https://link.springer.com/article/10.1007/s00203-003-0644-2.

Title:
Specificity grouping of the accessory gene regulator quorum-sensing system of Staphylococcus epidermidis is linked to infection | Archives of Microbiology
Description:
Staphylococcus epidermidis represents the most frequent pathogen involved in nosocomial infections and infections of indwelling medical devices. The strain-to-strain variation of the gene encoding the quorum-sensing pheromone of S. epidermidis as well as the correlation between specificity groups and origin from infection were determined. The pro-pheromone gene was highly conserved and showed infrequent, non-synonymous, single-nucleotide polymorphisms that led to conservative amino acid exchanges only. Importantly, one specificity group was significantly more frequent among strains isolated from infection. The finding that quorum-sensing specificity groups are linked to infection demonstrates the relevance of quorum-sensing for virulence in this critical human pathogen and contributes to the scientific basis needed for the development of quorum-sensing-targeting drugs.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Education
Social Networks

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,626,432 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

The income method remains a mystery to us.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

article, staphylococcus, google, scholar, epidermidis, otto, cas, pubmed, quorumsensing, infection, privacy, cookies, specificity, gene, system, pheromone, agr, infect, content, publish, search, virulence, access, bacterial, novick, aureus, götz, vuong, data, information, log, journal, research, accessory, regulator, linked, carmody, michael, infections, groups, strains, human, discover, national, control, microbiol, immun, peptide, download, author,

Topics {✒️}

month download article/chapter quorum-sensing-targeting drugs staphylococcal quorum-sensing pheromone bacterial interference caused human bacterial pathogenesis quorum-sensing specificity groups quorum-sensing pheromone quorum-sensing control privacy choices/manage cookies full article pdf carmody & michael otto pro-pheromone gene high genetic variability autoinducing peptide variants agr deletion mutant european economic area scope submit manuscript indwelling medical devices single-nucleotide polymorphisms scientific basis needed receptor-histidine kinase rocky mountain laboratories quorum-sensing staphylococcus epidermidis infections conditions privacy policy critical human pathogen cell density control staphylococcal virulence mediated article carmody article archives accepting optional cookies pheromone cross-inhibition author information authors frequent pathogen involved journal finder publish article log staphylococcus epidermidis check access instant access michael otto gene encoding pheromone peptide article cite related subjects agr groups staphylococcus aureus specificity grouping privacy policy personal data nosocomial infections

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Specificity grouping of the accessory gene regulator quorum-sensing system of Staphylococcus epidermidis is linked to infection
         description: Staphylococcus epidermidis represents the most frequent pathogen involved in nosocomial infections and infections of indwelling medical devices. The strain-to-strain variation of the gene encoding the quorum-sensing pheromone of S. epidermidis as well as the correlation between specificity groups and origin from infection were determined. The pro-pheromone gene was highly conserved and showed infrequent, non-synonymous, single-nucleotide polymorphisms that led to conservative amino acid exchanges only. Importantly, one specificity group was significantly more frequent among strains isolated from infection. The finding that quorum-sensing specificity groups are linked to infection demonstrates the relevance of quorum-sensing for virulence in this critical human pathogen and contributes to the scientific basis needed for the development of quorum-sensing-targeting drugs.
         datePublished:2004-01-09T00:00:00Z
         dateModified:2004-01-09T00:00:00Z
         pageStart:250
         pageEnd:253
         sameAs:https://doi.org/10.1007/s00203-003-0644-2
         keywords:
             Staphylococcus epidermidis
            Infection
            Quorum-sensing
            Microbiology
            Microbial Ecology
            Biochemistry
            general
            Cell Biology
            Biotechnology
            Ecology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00203-003-0644-2/MediaObjects/s00203-003-0644-2flb1.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00203-003-0644-2/MediaObjects/s00203-003-0644-2flb2.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00203-003-0644-2/MediaObjects/s00203-003-0644-2flb3.gif
         isPartOf:
            name:Archives of Microbiology
            issn:
               1432-072X
               0302-8933
            volumeNumber:181
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:A. B. Carmody
               affiliation:
                     name:The National Institutes of Health
                     address:
                        name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael Otto
               affiliation:
                     name:The National Institutes of Health
                     address:
                        name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Specificity grouping of the accessory gene regulator quorum-sensing system of Staphylococcus epidermidis is linked to infection
      description: Staphylococcus epidermidis represents the most frequent pathogen involved in nosocomial infections and infections of indwelling medical devices. The strain-to-strain variation of the gene encoding the quorum-sensing pheromone of S. epidermidis as well as the correlation between specificity groups and origin from infection were determined. The pro-pheromone gene was highly conserved and showed infrequent, non-synonymous, single-nucleotide polymorphisms that led to conservative amino acid exchanges only. Importantly, one specificity group was significantly more frequent among strains isolated from infection. The finding that quorum-sensing specificity groups are linked to infection demonstrates the relevance of quorum-sensing for virulence in this critical human pathogen and contributes to the scientific basis needed for the development of quorum-sensing-targeting drugs.
      datePublished:2004-01-09T00:00:00Z
      dateModified:2004-01-09T00:00:00Z
      pageStart:250
      pageEnd:253
      sameAs:https://doi.org/10.1007/s00203-003-0644-2
      keywords:
          Staphylococcus epidermidis
         Infection
         Quorum-sensing
         Microbiology
         Microbial Ecology
         Biochemistry
         general
         Cell Biology
         Biotechnology
         Ecology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00203-003-0644-2/MediaObjects/s00203-003-0644-2flb1.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00203-003-0644-2/MediaObjects/s00203-003-0644-2flb2.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00203-003-0644-2/MediaObjects/s00203-003-0644-2flb3.gif
      isPartOf:
         name:Archives of Microbiology
         issn:
            1432-072X
            0302-8933
         volumeNumber:181
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:A. B. Carmody
            affiliation:
                  name:The National Institutes of Health
                  address:
                     name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael Otto
            affiliation:
                  name:The National Institutes of Health
                  address:
                     name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Archives of Microbiology
      issn:
         1432-072X
         0302-8933
      volumeNumber:181
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:The National Institutes of Health
      address:
         name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
         type:PostalAddress
      name:The National Institutes of Health
      address:
         name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:A. B. Carmody
      affiliation:
            name:The National Institutes of Health
            address:
               name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
               type:PostalAddress
            type:Organization
      name:Michael Otto
      affiliation:
            name:The National Institutes of Health
            address:
               name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
      name:Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, The National Institutes of Health, Hamilton, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(63)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.5s.

LINK . SPRINGER . COM {}