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Title:
Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities? | Osteoporosis International
Description:
Osteoporosis and atherosclerosis, two multifactorial and degenerative entities, are major public health problems. These diseases accompany the aging process and share common risk factors. Furthermore, several common pathophysiological factors have been suggested. These include similar molecular pathways involving bone and vascular mineralization, estrogen deficiency, parathyroid hormone, homocysteine, lipid oxidation products, inflammatory process, as well as vitamin D and K. Moreover, the use of statins, biphosphonates, beta-blockers and experimental dual-purpose therapies based on the biological linkage of the above entities may simultaneously benefit bone loss and vascular disease. This review considers a potential link between osteoporosis and atherosclerosis beyond aging. These common factors may lead to appropriate treatment strategies.
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google, scholar, pubmed, cas, bone, women, int, osteoporosis, density, study, mineral, clin, disease, tissue, atherosclerosis, postmenopausal, calcif, risk, calcification, article, med, fractures, vascular, vitamin, statins, coronary, loss, cardiovascular, endocrinol, osteoporos, effects, factors, metab, human, invest, receptor, levels, related, osteoporotic, men, association, low, stroke, patients, biol, serum, aortic, normal, mass, res,
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month download article/chapter large-scale angiographic cohort prevent post-translational prenylation carotid intima-media thickness hmg-coa reductase inhibitors ovariectomy-induced bone loss ldl-receptor related proteins longitudinal population-based study age-dependent degenerative processes early coronary disease dual-purpose therapies metabolic risk factors privacy choices/manage cookies peripheral arterial disease full article pdf t-cell factor serum hscrp concentration receptor gene polymorphisms suppresses adipogenic differentiation promote adipogenic differentiation orr-walker bj coronary artery disease receptor gene variant receptor bsmi polymorphism serum osteoprotegerin levels low bone density coronary heart disease msx2 promotes osteogenesis 4s study group population-based study bone-mineral loss bone mineral density carotid plaque echogenicity marrow stromal cells framingham heart study high blood pressure wnt signal transduction mammalian myotubes induced activating osteoclasts browner ws gtp-binding proteins bone morphogenetic proteins calcification-regulating proteins lipid oxidation products low bone mass body composition study rancho bernardo study european economic area scope submit manuscript melton lj 3rd
Questions {β}
- Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities?
- Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities?
- Bienz M (1998) TCF: transcriptional activator or repressor?
- Christen WG, Ajani UA, Glynn RJ et al (2000) Blood levels of homocysteine and increased risks of cardiovascular disease: causal or casual?
- Collins T, Cybulsky MI (2001) NF-kB: pivotal mediator or innocent bystander in atherogenesis?
- Stevenson JC, Lees B, Devenport M et al (1989) Determinants of bone density in normal women: risk factors for future osteoporosis?
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headline:Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities?
description:Osteoporosis and atherosclerosis, two multifactorial and degenerative entities, are major public health problems. These diseases accompany the aging process and share common risk factors. Furthermore, several common pathophysiological factors have been suggested. These include similar molecular pathways involving bone and vascular mineralization, estrogen deficiency, parathyroid hormone, homocysteine, lipid oxidation products, inflammatory process, as well as vitamin D and K. Moreover, the use of statins, biphosphonates, beta-blockers and experimental dual-purpose therapies based on the biological linkage of the above entities may simultaneously benefit bone loss and vascular disease. This review considers a potential link between osteoporosis and atherosclerosis beyond aging. These common factors may lead to appropriate treatment strategies.
datePublished:2008-05-29T00:00:00Z
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Arterial calcification atherosclerosis
Biphosphonates
Fractures
Osteoporosis
Statins
Orthopedics
Endocrinology
Rheumatology
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headline:Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities?
description:Osteoporosis and atherosclerosis, two multifactorial and degenerative entities, are major public health problems. These diseases accompany the aging process and share common risk factors. Furthermore, several common pathophysiological factors have been suggested. These include similar molecular pathways involving bone and vascular mineralization, estrogen deficiency, parathyroid hormone, homocysteine, lipid oxidation products, inflammatory process, as well as vitamin D and K. Moreover, the use of statins, biphosphonates, beta-blockers and experimental dual-purpose therapies based on the biological linkage of the above entities may simultaneously benefit bone loss and vascular disease. This review considers a potential link between osteoporosis and atherosclerosis beyond aging. These common factors may lead to appropriate treatment strategies.
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Biphosphonates
Fractures
Osteoporosis
Statins
Orthopedics
Endocrinology
Rheumatology
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