We are analyzing https://link.springer.com/article/10.1007/s00018-008-8321-x.

Title:
Serum amyloid A: An acute-phase protein involved in tumour pathogenesis | Cellular and Molecular Life Sciences
Description:
The synthesis of acute-phase protein serum amyloid A (SAA) is largely regulated by inflammation- associated cytokines and a high concentration of circulating SAA may represent an ideal marker for acute and chronic inflammatory diseases. However, SAA is also synthesized in extrahepatic tissues, e.g. human carcinoma metastases and cancer cell lines. An increasing body of in vitro data supports the concept of involvement of SAA in carcinogenesis and neoplastic diseases. Accumulating evidence suggests that SAA might be included in a group of biomarkers to detect a pattern of physiological events that reflect the growth of malignancy and host response. This review is meant to provide a broad overview of the many ways that SAA could contribute to tumour development, and accelerate tumour progression and metastasis, and to gain a better understanding of this acute-phase reactant as a possible link between chronic inflammation and neoplasia.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Telecommunications
Social Networks
Education

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't figure out the monetization strategy.

Many websites are intended to earn money, but some serve to share ideas or build connections. Websites exist for all kinds of purposes. This might be one of them. Link.springer.com might be plotting its profit, but the way they're doing it isn't detectable yet.

Keywords {🔍}

article, saa, access, serum, amyloid, privacy, cookies, content, protein, tumour, data, information, publish, search, molecular, acutephase, malle, open, log, journal, research, life, review, august, sodinsemrl, kovacevic, inflammation, acute, carcinoma, cell, biomarkers, discover, author, springer, optional, personal, parties, policy, find, track, cellular, sciences, involved, pathogenesis, published, cite, explore, chronic, diseases, institution,

Topics {✒️}

acute-phase protein involved month download article/chapter accelerate tumour progression human carcinoma metastases related subjects cancer cell lines acute-phase reactant tumour pathogenesis privacy choices/manage cookies biomarkers full article pdf tumour development predicting acute onset serum amyloid author correspondence check access instant access european economic area scope submit manuscript accumulating evidence suggests pd-1 blockade resistance vitro data supports conditions privacy policy accepting optional cookies chronic inflammatory diseases university medical centre chronic inflammation article cellular journal finder publish article log article number 9 protein life sci article cite personal data privacy policy cell article malle information molecular medicine molecular biology inflammation optional cookies manage preferences medical university kovacevic division circulating saa subscription content similar content data protection

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Serum amyloid A: An acute-phase protein involved in tumour pathogenesis
         description:The synthesis of acute-phase protein serum amyloid A (SAA) is largely regulated by inflammation- associated cytokines and a high concentration of circulating SAA may represent an ideal marker for acute and chronic inflammatory diseases. However, SAA is also synthesized in extrahepatic tissues, e.g. human carcinoma metastases and cancer cell lines. An increasing body of in vitro data supports the concept of involvement of SAA in carcinogenesis and neoplastic diseases. Accumulating evidence suggests that SAA might be included in a group of biomarkers to detect a pattern of physiological events that reflect the growth of malignancy and host response. This review is meant to provide a broad overview of the many ways that SAA could contribute to tumour development, and accelerate tumour progression and metastasis, and to gain a better understanding of this acute-phase reactant as a possible link between chronic inflammation and neoplasia.
         datePublished:2008-08-23T00:00:00Z
         dateModified:2008-08-23T00:00:00Z
         pageStart:9
         pageEnd:26
         sameAs:https://doi.org/10.1007/s00018-008-8321-x
         keywords:
            SAA
            inflammation
            renal cell carcinoma
            extracellular matrix
            rheumatoid arthritis
            FPRL-1
            MMP
            proteomics
            Cell Biology
            Biomedicine
            general
            Life Sciences
            Biochemistry
         image:
         isPartOf:
            name:Cellular and Molecular Life Sciences
            issn:
               1420-9071
               1420-682X
            volumeNumber:66
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Birkhäuser-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:E. Malle
               affiliation:
                     name:Medical University of Graz
                     address:
                        name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:S. Sodin-Semrl
               affiliation:
                     name:University Medical Centre
                     address:
                        name:Division of Internal Medicine, Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:A. Kovacevic
               affiliation:
                     name:Medical University of Graz
                     address:
                        name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Serum amyloid A: An acute-phase protein involved in tumour pathogenesis
      description:The synthesis of acute-phase protein serum amyloid A (SAA) is largely regulated by inflammation- associated cytokines and a high concentration of circulating SAA may represent an ideal marker for acute and chronic inflammatory diseases. However, SAA is also synthesized in extrahepatic tissues, e.g. human carcinoma metastases and cancer cell lines. An increasing body of in vitro data supports the concept of involvement of SAA in carcinogenesis and neoplastic diseases. Accumulating evidence suggests that SAA might be included in a group of biomarkers to detect a pattern of physiological events that reflect the growth of malignancy and host response. This review is meant to provide a broad overview of the many ways that SAA could contribute to tumour development, and accelerate tumour progression and metastasis, and to gain a better understanding of this acute-phase reactant as a possible link between chronic inflammation and neoplasia.
      datePublished:2008-08-23T00:00:00Z
      dateModified:2008-08-23T00:00:00Z
      pageStart:9
      pageEnd:26
      sameAs:https://doi.org/10.1007/s00018-008-8321-x
      keywords:
         SAA
         inflammation
         renal cell carcinoma
         extracellular matrix
         rheumatoid arthritis
         FPRL-1
         MMP
         proteomics
         Cell Biology
         Biomedicine
         general
         Life Sciences
         Biochemistry
      image:
      isPartOf:
         name:Cellular and Molecular Life Sciences
         issn:
            1420-9071
            1420-682X
         volumeNumber:66
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Birkhäuser-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:E. Malle
            affiliation:
                  name:Medical University of Graz
                  address:
                     name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:S. Sodin-Semrl
            affiliation:
                  name:University Medical Centre
                  address:
                     name:Division of Internal Medicine, Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:A. Kovacevic
            affiliation:
                  name:Medical University of Graz
                  address:
                     name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Cellular and Molecular Life Sciences
      issn:
         1420-9071
         1420-682X
      volumeNumber:66
Organization:
      name:Birkhäuser-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Medical University of Graz
      address:
         name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
         type:PostalAddress
      name:University Medical Centre
      address:
         name:Division of Internal Medicine, Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
         type:PostalAddress
      name:Medical University of Graz
      address:
         name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:E. Malle
      affiliation:
            name:Medical University of Graz
            address:
               name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:S. Sodin-Semrl
      affiliation:
            name:University Medical Centre
            address:
               name:Division of Internal Medicine, Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
               type:PostalAddress
            type:Organization
      name:A. Kovacevic
      affiliation:
            name:Medical University of Graz
            address:
               name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
      name:Division of Internal Medicine, Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
      name:Center of Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(29)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.19s.

LINK . SPRINGER . COM {}