We are analyzing https://link.springer.com/article/10.1007/bf03167050.

Title:
Serum and gene expression levels of leptin and adiponectin in rats susceptible or resistant to diet-induced obesity | Journal of Physiology and Biochemistry
Description:
The aim of the present study was to identify the role of leptin and adiponectin in the development of resistance or susceptibility to diet-induced obesity in rats. For this purpose, male Wistar rats were fed with standard laboratory diet (control group) or cafeteria diet. After 15 days, two groups of rats with different response respect to the cafeteria diet were identified, and were assigned as diet-induced obesity (DIO) and diet resistant (DR) rats. The high-fat diet induced a very dignificant increase in both body and fat mass weight in DIO group. However, DR rats, gained even less weight than control-fed animals. Food intake was increased in cafeteria-fed rats (both DIO and DR) in comparison to control group; but hyperphagia was higher in DIO rats. In addition, feed efficiency (the ratio of weight gained to calories consumed) was significantly decreased in DR as compared to DIO rats. Regarding leptin, a significant increase in both adipose tissue gene expression and serum levels was observed in DIO rats in comparison with other groups (control and DR). A significant increase in both adiponectin circulating levels and adipose tissue mRNA expression was also observed in DIO animals as compared with the other groups. These data suggest that the susceptibility to obesity of DIO rats might be secondary, at least in part, to an earlier development of leptin resistance, which could lead to alterations in food intake (hyperphagia) and energetic metabolism. However, neither changes in leptin or adiponectin seem to be involved in the adaptive mechanisms that confer resistance to high fat intake.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Health & Fitness
Fitness & Wellness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

Not all websites are made for profit; some exist to inform or educate users. Or any other reason why people make websites. And this might be the case. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

google, scholar, article, cas, pubmed, physiol, rats, dio, martínez, obesity, los, marti, leptin, biochem, levin, adiponectin, leptina, ratas, obesidad, dieta, morenoaliaga, diet, control, privacy, cookies, content, journal, expression, dietinduced, adiponectina, access, metab, data, publish, search, levels, pérezmatute, resistance, weight, resistencia, grupo, res, endocrinol, zhang, dunnmeynell, regul, integr, comp, med, nature,

Topics {✒️}

los animales control month download article/chapter dieta de cafetería la adiponectina la leptina la obesidad high-fat diet induced la susceptibilidad en cuanto moreno-aliaga rights diet-induced obesity full article pdf fat mass weight male wistar rats privacy choices/manage cookies de miguel scheduled high-fat article pérez-echarri high fat intake gene expression levels adiponectin circulating levels high-sucrose diet standard laboratory diet european economic area scope submit manuscript se observó esto datos sugieren elucidating platelet dysfunction provocan resistencia conditions privacy policy check access instant access grupo control leptin resistance accepting optional cookies energetic metabolism moreno-aliaga article journal journal finder publish main content log control-fed animals confer resistance antagonist article 28 article log cafeteria-fed rats article cite susceptibilidad pérez-matute susceptibility dr rats

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Serum and gene expression levels of leptin and adiponectin in rats susceptible or resistant to diet-induced obesity
         description:The aim of the present study was to identify the role of leptin and adiponectin in the development of resistance or susceptibility to diet-induced obesity in rats. For this purpose, male Wistar rats were fed with standard laboratory diet (control group) or cafeteria diet. After 15 days, two groups of rats with different response respect to the cafeteria diet were identified, and were assigned as diet-induced obesity (DIO) and diet resistant (DR) rats. The high-fat diet induced a very dignificant increase in both body and fat mass weight in DIO group. However, DR rats, gained even less weight than control-fed animals. Food intake was increased in cafeteria-fed rats (both DIO and DR) in comparison to control group; but hyperphagia was higher in DIO rats. In addition, feed efficiency (the ratio of weight gained to calories consumed) was significantly decreased in DR as compared to DIO rats. Regarding leptin, a significant increase in both adipose tissue gene expression and serum levels was observed in DIO rats in comparison with other groups (control and DR). A significant increase in both adiponectin circulating levels and adipose tissue mRNA expression was also observed in DIO animals as compared with the other groups. These data suggest that the susceptibility to obesity of DIO rats might be secondary, at least in part, to an earlier development of leptin resistance, which could lead to alterations in food intake (hyperphagia) and energetic metabolism. However, neither changes in leptin or adiponectin seem to be involved in the adaptive mechanisms that confer resistance to high fat intake.
         datePublished:
         dateModified:
         pageStart:333
         pageEnd:342
         sameAs:https://doi.org/10.1007/BF03167050
         keywords:
            Obesity
            Susceptibility
            Resistance
            Leptin
            Adiponectin
            Obesidad
            Susceptibilidad
            Resistencia
            Leptina
            Adiponectina
            Biomedicine
            general
            Human Physiology
            Animal Physiology
         image:
         isPartOf:
            name:Journal of Physiology and Biochemistry
            issn:
               1877-8755
               1138-7548
            volumeNumber:61
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Netherlands
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:N. Pérez-Echarri
               affiliation:
                     name:University of Navarra
                     address:
                        name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:P. Pérez-Matute
               affiliation:
                     name:University of Navarra
                     address:
                        name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:J. A. Martínez
               affiliation:
                     name:University of Navarra
                     address:
                        name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:A. Marti
               affiliation:
                     name:University of Navarra
                     address:
                        name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M. J. Moreno-Aliaga
               affiliation:
                     name:University of Navarra
                     address:
                        name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Serum and gene expression levels of leptin and adiponectin in rats susceptible or resistant to diet-induced obesity
      description:The aim of the present study was to identify the role of leptin and adiponectin in the development of resistance or susceptibility to diet-induced obesity in rats. For this purpose, male Wistar rats were fed with standard laboratory diet (control group) or cafeteria diet. After 15 days, two groups of rats with different response respect to the cafeteria diet were identified, and were assigned as diet-induced obesity (DIO) and diet resistant (DR) rats. The high-fat diet induced a very dignificant increase in both body and fat mass weight in DIO group. However, DR rats, gained even less weight than control-fed animals. Food intake was increased in cafeteria-fed rats (both DIO and DR) in comparison to control group; but hyperphagia was higher in DIO rats. In addition, feed efficiency (the ratio of weight gained to calories consumed) was significantly decreased in DR as compared to DIO rats. Regarding leptin, a significant increase in both adipose tissue gene expression and serum levels was observed in DIO rats in comparison with other groups (control and DR). A significant increase in both adiponectin circulating levels and adipose tissue mRNA expression was also observed in DIO animals as compared with the other groups. These data suggest that the susceptibility to obesity of DIO rats might be secondary, at least in part, to an earlier development of leptin resistance, which could lead to alterations in food intake (hyperphagia) and energetic metabolism. However, neither changes in leptin or adiponectin seem to be involved in the adaptive mechanisms that confer resistance to high fat intake.
      datePublished:
      dateModified:
      pageStart:333
      pageEnd:342
      sameAs:https://doi.org/10.1007/BF03167050
      keywords:
         Obesity
         Susceptibility
         Resistance
         Leptin
         Adiponectin
         Obesidad
         Susceptibilidad
         Resistencia
         Leptina
         Adiponectina
         Biomedicine
         general
         Human Physiology
         Animal Physiology
      image:
      isPartOf:
         name:Journal of Physiology and Biochemistry
         issn:
            1877-8755
            1138-7548
         volumeNumber:61
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Netherlands
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:N. Pérez-Echarri
            affiliation:
                  name:University of Navarra
                  address:
                     name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:P. Pérez-Matute
            affiliation:
                  name:University of Navarra
                  address:
                     name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:J. A. Martínez
            affiliation:
                  name:University of Navarra
                  address:
                     name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:A. Marti
            affiliation:
                  name:University of Navarra
                  address:
                     name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M. J. Moreno-Aliaga
            affiliation:
                  name:University of Navarra
                  address:
                     name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Journal of Physiology and Biochemistry
      issn:
         1877-8755
         1138-7548
      volumeNumber:61
Organization:
      name:Springer Netherlands
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Navarra
      address:
         name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
         type:PostalAddress
      name:University of Navarra
      address:
         name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
         type:PostalAddress
      name:University of Navarra
      address:
         name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
         type:PostalAddress
      name:University of Navarra
      address:
         name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
         type:PostalAddress
      name:University of Navarra
      address:
         name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:N. Pérez-Echarri
      affiliation:
            name:University of Navarra
            address:
               name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
               type:PostalAddress
            type:Organization
      name:P. Pérez-Matute
      affiliation:
            name:University of Navarra
            address:
               name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
               type:PostalAddress
            type:Organization
      name:J. A. Martínez
      affiliation:
            name:University of Navarra
            address:
               name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
               type:PostalAddress
            type:Organization
      name:A. Marti
      affiliation:
            name:University of Navarra
            address:
               name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
               type:PostalAddress
            type:Organization
      name:M. J. Moreno-Aliaga
      affiliation:
            name:University of Navarra
            address:
               name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
      name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
      name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
      name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
      name:Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(126)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

3.91s.

LINK . SPRINGER . COM {}