We are analyzing https://link.springer.com/article/10.1007/bf01806023.

Title:
Tissue mast cells in breast cancer | Breast Cancer Research and Treatment
Description:
The total number of mast cells and the number of such cells observed within and at the periphery of invasive breast cancers from 424 patients enrolled in protocol 4 of the National Surgical Adjuvant Breast Project were correlated with 38 other pathologic and 6 clinical features. High total mast cell counts as well as those within and at the periphery of the cancers were found to be significantly (p≤.05) associated with a patient age less than 50 years and the degree of tumor lymphoid cell reaction. The latter has also been found to be related to young age and other pathologic characteristics related to mast cell content. This suggests that the mast cells may simply represent another cell type of this reactive change. No differences in 10 year disease-free survival were detected in patients without mast cells and those exhibiting varying numbers of such cells. This information indicates that identifiable mast cells do not represent a prognostic pathologic discriminant in patients with breast cancer. However, this does not unequivocally exclude a role of mast cell secretory products, since only intact and not degranulated or disrupted forms of these cells can be counted.
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Keywords {🔍}

breast, cancer, fisher, cells, google, scholar, mast, pubmed, article, national, surgical, adjuvant, project, sass, protocol, content, pathologic, privacy, cookies, research, tissue, watkins, cell, tumor, information, publish, search, treatment, edwin, richard, gloria, jasbir, johal, bernard, cancers, patients, related, access, findings, usa, data, log, journal, year, survival, products, discover, human, res, pathology,

Topics {✒️}

month download article/chapter year disease-free survival human breast cancer invasive breast cancers jasbir johal invasive breast cancer privacy choices/manage cookies identifiable mast cells neoplastic mast cells tissue mast cells year treatment failure mast cell content mast-cell content full article pdf tumor lymphoid response european economic area nodal sinus reaction life table method conditions privacy policy breast cancer exhibiting varying numbers prognostic pathologic discriminant accepting optional cookies mast cells growth-promoting activity pathologic characteristics related cancer res 20 journal finder publish check access scar cancers instant access article fisher cells observed privacy policy personal data protocol 4 rights article log treatment aims cell type related subjects books a tumor tissue analyzing survival optional cookies manage preferences total number subscription content paul ehrlich arch path 79 preliminary report

Questions {❓}

Thoresen S, Thoresen T, Harveit F: Does progesterone receptor in human breast cancer reflect the mast-cell content of the tumor tissue?

Schema {🗺️}

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