We are analyzing https://link.springer.com/article/10.1007/bf01215983.

Title:
Establishment and characteristics of two new human mammary carcinoma lines serially transplantable in nude mice | Journal of Cancer Research and Clinical Oncology
Description:
Two human mammary carcinomas of postmenopausal women were successfully transplanted into nude mice. Both tumours were classified as epidermal-growth-factor-, oestradiol- and progesterone-receptor-negative and c-erbB2-protein-positive. Histological studies of the primary tumours (4000 and 4151) revealed ductal invasive mammary carcinomas. In the first passages the precondition for the growth of breast carcinoma 4000 were pretreatments of the nude mice with oestradiol and peanut oil before transplantation. The mammary carcinomas 4000 and 4151 described here are suitable for in vivo testing of antineoplastic substances and for biological studies.
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Keywords {🔍}

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Topics {✒️}

c-erbb2-protein-positive c-erbb-2 protein overexpression progesterone-receptor-negative month download article/chapter c-erbb-2 oncoprotein expression c-erbb-2 oncogene expression de ipolyi pd mammary tumor cells breast cancer cells gerd jörg saul clinical oncology aims human mammary carcinomas c-erbb-2 expression human breast cancer human breast carcinomas mouse mammary fibroblast privacy choices/manage cookies advanced breast cancer breast-cancer occurrence full article pdf human tumor xenografts test models van leer em breast carcinoma 4000 european economic area extremely low tumorigenicity related subjects uninvolved lymph nodes improved conventional conditions anticancer drug development robert-rössle-strasse 10 universitätsklinikum rudolf virchow robert-rössle-klinik mammary carcinomas 4000 theher-2/neu oncogene conditions privacy policy accepting optional cookies cancer research november 1993 volume 119 igf-ii mrna breast cancer journal finder publish postmenopausal women article naundorf check access instant access mammary epithelium epidermal-growth-factor slamon dj nude mice

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