We are analyzing https://link.springer.com/article/10.1007/bf01102943.

Title:
Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice | Brain Cell Biology
Description:
The brains of mice fed since weaning on a diet containing 0.5% cuprizone show an astrocytosis, status spongiosus and oligodendrocyte degeneration. Degenerating oligodendrocytes were first seen at one week and increased in number after two weeks on the diet. By five weeks many axons were demyelinated and remyelinating oligodendrocytes were identified. The origin of these cells is discussed. Astrocytes and microglial cells were involved in the removal of the vacuolated myelin.
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Keywords {🔍}

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Topics {✒️}

month download article/chapter related subjects cuprizone-induced brain edema privacy choices/manage cookies december 1972 volume 1 full article pdf experimental allergic encephalomyelitis chronic copper poisoning central nervous system alkyl tin intoxication european economic area isonicotinic acid hydrazide conditions privacy policy cerebral oedema induced oligodendrocyte degeneration adult rat brain rat optic nerves isoniazidinduced brain oedema electron microscopic studies enzyme histochemical observations cuprizone-induced demyelination check access instant access accepting optional cookies electron microscope study spongiform encephalopathy induced subependymal cell electron microscopic analysis electron microscopic study central myelin sheath main content log electron microscopic identification glial cellsin vitro blakemore rights journal finder publish status spongiosus microglial reactions spinal cord article blakemore brain research 13 �sclerosis microglial cells article log privacy policy experimental lesion cuprizone intoxication personal data electron microscopic article journal andralston iii

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