We are analyzing https://link.springer.com/article/10.1007/bf02603120.

Title:
Progressive sequence alignment as a prerequisitetto correct phylogenetic trees | Journal of Molecular Evolution
Description:
A progressive alignment method is described that utilizes the Needleman and Wunsch pairwise alignment algorithm iteratively to achieve the multiple alignment of a set of protein sequences and to construct an evolutionary tree depicting their relationship. The sequences are assumed a priori to share a common ancestor, and the trees are constructed from difference matrices derived directly from the multiple alignment. The thrust of the method involves putting more trust in the comparison of recently diverged sequences than in those evolved in the distant past. In particular, this rule is followed: “once a gap, always a gap”. The method has been applied to three sets of protein sequences: 7 superoxide dismutases, 11 globins, and 9 tyrosine kinase-like sequences. Multiple alignments and phylogenetic trees for these sets of sequences were determined and compared with trees derived by conventional pairwise treatments. In several instances, the progressive method led to trees that appeared to be more in line with biological expectations than were trees obtained by more commonly used methods.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Education
Fitness & Wellness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,625,932 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Link.springer.com might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

google, scholar, article, cas, pubmed, sequence, mol, trees, method, sequences, superoxide, evol, evolutionary, dismutase, biol, protein, research, alignment, phylogenetic, doolittle, structure, dayhoff, data, usa, amino, acid, fitch, privacy, cookies, content, journal, search, molecular, multiple, bannister, publish, evolution, progressive, feng, sets, access, related, proteins, leiognathi, proc, natl, acad, sci, atlas, national,

Topics {✒️}

month download article/chapter cu-zn superoxide dismutase copper/zinc superoxide dismutase sequence phylogeny research full article pdf amino acid sequence human superoxide dismutase privacy choices/manage cookies progressive sequence alignment article feng sequence homologies amonge evolutionarily related groupings distantly related species conventional pairwise treatments multiple alignments related subjects molecular evolution aims molecular restoration studies progressive alignment method progressive method led estimated phylogenetic trees amino acid sequences calculating evolutionary trees european economic area silver spring md de jong ww kim s-ma ponyfish tophotobacterium leiognathi conditions privacy policy protein sequence method involves putting general method applicable article journal evolutionary tree depicting recently diverged sequences accepting optional cookies johnson ms dendrogram problem posed california-san diego superoxide dismutase journal finder publish natural gene transfer mckay wm article log maximum parsimony method main content log coli ribosomal proteins molecular data sets multiple alignment article cite

Questions {❓}

Doolittle RF (1981) Similar amino acid sequences: chance or common ancestry?
Leunissen JAM, De Jong WW (1986) Copper/zinc superoxide dismutase: how likely is gene transfer from ponyfish toPhotobacterium leiognathi?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Progressive sequence alignment as a prerequisitetto correct phylogenetic trees
         description:A progressive alignment method is described that utilizes the Needleman and Wunsch pairwise alignment algorithm iteratively to achieve the multiple alignment of a set of protein sequences and to construct an evolutionary tree depicting their relationship. The sequences are assumed a priori to share a common ancestor, and the trees are constructed from difference matrices derived directly from the multiple alignment. The thrust of the method involves putting more trust in the comparison of recently diverged sequences than in those evolved in the distant past. In particular, this rule is followed: “once a gap, always a gap”. The method has been applied to three sets of protein sequences: 7 superoxide dismutases, 11 globins, and 9 tyrosine kinase-like sequences. Multiple alignments and phylogenetic trees for these sets of sequences were determined and compared with trees derived by conventional pairwise treatments. In several instances, the progressive method led to trees that appeared to be more in line with biological expectations than were trees obtained by more commonly used methods.
         datePublished:
         dateModified:
         pageStart:351
         pageEnd:360
         sameAs:https://doi.org/10.1007/BF02603120
         keywords:
            Multiple sequence alignments
            Evolutionary trees
            Evolutionary Biology
            Microbiology
            Plant Sciences
            Plant Genetics and Genomics
            Animal Genetics and Genomics
            Cell Biology
         image:
         isPartOf:
            name:Journal of Molecular Evolution
            issn:
               1432-1432
               0022-2844
            volumeNumber:25
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Da-Fei Feng
               affiliation:
                     name:University of California-San Diego
                     address:
                        name:Department of Chemistry, University of California-San Diego, La Jolla, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Russell F. Doolittle
               affiliation:
                     name:University of California-San Diego
                     address:
                        name:Department of Chemistry, University of California-San Diego, La Jolla, USA
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Progressive sequence alignment as a prerequisitetto correct phylogenetic trees
      description:A progressive alignment method is described that utilizes the Needleman and Wunsch pairwise alignment algorithm iteratively to achieve the multiple alignment of a set of protein sequences and to construct an evolutionary tree depicting their relationship. The sequences are assumed a priori to share a common ancestor, and the trees are constructed from difference matrices derived directly from the multiple alignment. The thrust of the method involves putting more trust in the comparison of recently diverged sequences than in those evolved in the distant past. In particular, this rule is followed: “once a gap, always a gap”. The method has been applied to three sets of protein sequences: 7 superoxide dismutases, 11 globins, and 9 tyrosine kinase-like sequences. Multiple alignments and phylogenetic trees for these sets of sequences were determined and compared with trees derived by conventional pairwise treatments. In several instances, the progressive method led to trees that appeared to be more in line with biological expectations than were trees obtained by more commonly used methods.
      datePublished:
      dateModified:
      pageStart:351
      pageEnd:360
      sameAs:https://doi.org/10.1007/BF02603120
      keywords:
         Multiple sequence alignments
         Evolutionary trees
         Evolutionary Biology
         Microbiology
         Plant Sciences
         Plant Genetics and Genomics
         Animal Genetics and Genomics
         Cell Biology
      image:
      isPartOf:
         name:Journal of Molecular Evolution
         issn:
            1432-1432
            0022-2844
         volumeNumber:25
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Da-Fei Feng
            affiliation:
                  name:University of California-San Diego
                  address:
                     name:Department of Chemistry, University of California-San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Russell F. Doolittle
            affiliation:
                  name:University of California-San Diego
                  address:
                     name:Department of Chemistry, University of California-San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Journal of Molecular Evolution
      issn:
         1432-1432
         0022-2844
      volumeNumber:25
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of California-San Diego
      address:
         name:Department of Chemistry, University of California-San Diego, La Jolla, USA
         type:PostalAddress
      name:University of California-San Diego
      address:
         name:Department of Chemistry, University of California-San Diego, La Jolla, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Da-Fei Feng
      affiliation:
            name:University of California-San Diego
            address:
               name:Department of Chemistry, University of California-San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
      name:Russell F. Doolittle
      affiliation:
            name:University of California-San Diego
            address:
               name:Department of Chemistry, University of California-San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Chemistry, University of California-San Diego, La Jolla, USA
      name:Department of Chemistry, University of California-San Diego, La Jolla, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(114)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.03s.

LINK . SPRINGER . COM {}