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Title:
The genetic basis of developmental stability. I. Relationships between stability, heterozygosity and genomic coadaptation | Genetica
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The genetic basis of developmental stability has been much debated over the last four decades. Two major hypotheses have been developed over this period, one that argues that the level of stability is a reflection of the underlying level of genomic heterozygosity and the other that stability reflects the general level of genomic coadaptation, or genic balance. In this paper I have attempted to critically review the evidence for these hypotheses from both practical and theoretical perspectives. On balance there is little convincing evidence to suggest that heterozygosity plays a significant role in the determination and maintenance of developmental stability, whereas there is considerable support for the genomic coadaptation hypothesis.
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- Developmental stability of rainbow trout hybrids: genomic coadaptation or heterozygosity?
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headline:The genetic basis of developmental stability. I. Relationships between stability, heterozygosity and genomic coadaptation
description:The genetic basis of developmental stability has been much debated over the last four decades. Two major hypotheses have been developed over this period, one that argues that the level of stability is a reflection of the underlying level of genomic heterozygosity and the other that stability reflects the general level of genomic coadaptation, or genic balance. In this paper I have attempted to critically review the evidence for these hypotheses from both practical and theoretical perspectives. On balance there is little convincing evidence to suggest that heterozygosity plays a significant role in the determination and maintenance of developmental stability, whereas there is considerable support for the genomic coadaptation hypothesis.
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Genetic Basis
General Level
Theoretical Perspective
Convincing Evidence
Animal Genetics and Genomics
Plant Genetics and Genomics
Evolutionary Biology
Human Genetics
Microbial Genetics and Genomics
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headline:The genetic basis of developmental stability. I. Relationships between stability, heterozygosity and genomic coadaptation
description:The genetic basis of developmental stability has been much debated over the last four decades. Two major hypotheses have been developed over this period, one that argues that the level of stability is a reflection of the underlying level of genomic heterozygosity and the other that stability reflects the general level of genomic coadaptation, or genic balance. In this paper I have attempted to critically review the evidence for these hypotheses from both practical and theoretical perspectives. On balance there is little convincing evidence to suggest that heterozygosity plays a significant role in the determination and maintenance of developmental stability, whereas there is considerable support for the genomic coadaptation hypothesis.
datePublished:
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pageStart:15
pageEnd:23
sameAs:https://doi.org/10.1007/BF02424502
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Significant Role
Genetic Basis
General Level
Theoretical Perspective
Convincing Evidence
Animal Genetics and Genomics
Plant Genetics and Genomics
Evolutionary Biology
Human Genetics
Microbial Genetics and Genomics
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