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Title:
Identification of a lobe in the adult human pancreas rich in pancreatic polypeptide | Diabetologia
Description:
Systematic sampling of human necropsy pancreases has revealed that pancreatic polypeptide (PP) cells are not distributed equally in the gland. PP-cells are the most abundant cell type in the posterior part of the pancreatic head while they are scarce or absent in the remainder of the gland. The PP-rich part of the head can be separated by blunt dissection from the pancreas as a discrete lobe. This lobe probably originates from the ventral pancreatic bud during embryogenesis. A quantitative study of the immunofluorescent endocrine cell types (insulin, glucagon, somatostatin and pancreatic polypeptide cells) in PP-rich and PP-poor regions of pancreases in 8 subjects with ages ranging from 33 fetal weeks to 80 years, showed that the proportions of the cell types were different in youngs and adults.
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google, scholar, pancreas, pancreatic, polypeptide, article, human, malaisselagae, orci, stefan, privacy, cookies, diabetologia, perrelet, cell, glucagon, content, publish, search, identification, lobe, download, cox, cells, geneva, data, information, journal, research, adult, explore, gland, endocrine, insulin, subjects, islets, langerhans, discover, baetens, distribution, pathol, anat, lancet, antibody, site, optional, personal, parties, policy, find,
Topics {✒️}
horseradish peroxidase-antihorseradish peroxidase soluble antigen-antibody complex pancreatic-polypeptide-rich regions explore progenitor proliferation privacy choices/manage cookies pancreatic polypeptide cells �pancreatic polypeptide”-cells îlots à glucagon main content log related subjects article malaisse-lagae abundant cell type stem cell factor simultaneously synthesizing glucagon european economic area electron microscopic immunocytochemistry electron microscopic cytology human developing pancreas conditions privacy policy ventral pancreatic bud pp-poor regions accepting optional cookies scope submit manuscript cellular storage site pp-rich part human necropsy pancreases search search journal finder publish de mey endocrine pancreas pancreatic polypeptide pancreatic polypeptide adult islets cell types article cite pancreatic islets random distribution regional distribution histology human pancreas pp-cells d-cells privacy policy personal data books a pp-rich cox rights canine pancreas optional cookies manage preferences
Questions {❓}
- Anatomic and hormonal markers for the ventral primordium in the human pancreas?
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mainEntity:
headline:Identification of a lobe in the adult human pancreas rich in pancreatic polypeptide
description:Systematic sampling of human necropsy pancreases has revealed that pancreatic polypeptide (PP) cells are not distributed equally in the gland. PP-cells are the most abundant cell type in the posterior part of the pancreatic head while they are scarce or absent in the remainder of the gland. The PP-rich part of the head can be separated by blunt dissection from the pancreas as a discrete lobe. This lobe probably originates from the ventral pancreatic bud during embryogenesis. A quantitative study of the immunofluorescent endocrine cell types (insulin, glucagon, somatostatin and pancreatic polypeptide cells) in PP-rich and PP-poor regions of pancreases in 8 subjects with ages ranging from 33 fetal weeks to 80 years, showed that the proportions of the cell types were different in youngs and adults.
datePublished:
dateModified:
pageStart:361
pageEnd:365
sameAs:https://doi.org/10.1007/BF01236270
keywords:
Pancreas
islets of Langerhans
insulin
glucagon
somatostatin
pancreatic polypeptide
immunohistochemistry
embryology
Internal Medicine
Metabolic Diseases
Human Physiology
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headline:Identification of a lobe in the adult human pancreas rich in pancreatic polypeptide
description:Systematic sampling of human necropsy pancreases has revealed that pancreatic polypeptide (PP) cells are not distributed equally in the gland. PP-cells are the most abundant cell type in the posterior part of the pancreatic head while they are scarce or absent in the remainder of the gland. The PP-rich part of the head can be separated by blunt dissection from the pancreas as a discrete lobe. This lobe probably originates from the ventral pancreatic bud during embryogenesis. A quantitative study of the immunofluorescent endocrine cell types (insulin, glucagon, somatostatin and pancreatic polypeptide cells) in PP-rich and PP-poor regions of pancreases in 8 subjects with ages ranging from 33 fetal weeks to 80 years, showed that the proportions of the cell types were different in youngs and adults.
datePublished:
dateModified:
pageStart:361
pageEnd:365
sameAs:https://doi.org/10.1007/BF01236270
keywords:
Pancreas
islets of Langerhans
insulin
glucagon
somatostatin
pancreatic polypeptide
immunohistochemistry
embryology
Internal Medicine
Metabolic Diseases
Human Physiology
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