We are analyzing https://link.springer.com/article/10.1007/bf00283614.

Title:
Human δ-aminolevulinate dehydratase: chromosomal localization to 9q34 by in situ hybridization | Human Genetics
Description:
The structural gene for human δ-aminolevulinate dehydratase (ALA-D) has been localized to chromosomal region 9q34 by in situ hybridization using a [125I]-labeled human δ-aminolevulinate dehydratase cDNA. Of the 150 silver grains analyzed, 25% were localized to chromosome 9q, while 12% and 8% were on chromosomes 1p and 13q, respectively. The single chromosomal region q34 had over 90% of the total grains observed on chromosome 9. In contrast, the grains on chromosomes 1p and 13q were dispersed, consistent with the absence of any human ALD-D pseudogenes. Southern blot analysis of somatic cell hybrids informative for ALA-D (Wang et al. 1985) also was consistent and supported the finding of only one locus for this heme biosynthetic enzyme.
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Keywords {🔍}

google, scholar, human, genet, chromosome, dehydratase, gene, δaminolevulinate, article, cell, hum, hybridization, assignment, usa, situ, desnick, regional, mouse, privacy, cookies, content, genetics, chromosomal, astrin, wetmur, bishop, chromosomes, somatic, access, proc, natl, acad, sci, information, publish, search, localization, alad, cdna, acid, genetic, anderson, cytogenet, linkage, analysis, data, log, journal, research, potluri,

Topics {✒️}

month download article/chapter southern blot analysis human δ-aminolevulinate dehydratase hepatic δ-aminolevulinate dehydratase δ-aminolevulinic acid dehydratase δ-aminolveulinic acid dehydratase autosomal glucose-6-phosphate dehydrogenase delta-aminolevulinate dehydrase deficiency human α-l-iduronidase codon-optimized hema gene reveal high-frequency rflps full-length cdna clone δ-aminolevulinate dehydratase somatic cell hybridization related subjects cold spring harbor full article pdf privacy choices/manage cookies human gene map human peripheral blood human porphobilinogen deaminase hereditary hepatic porphyria situ hybridization technique european economic area nail-patella syndrome dna fragments separated ribosomal rna species arredondo-vega fx γ-globin gene mount sinai school mouse erythroleukemia cells check access homologous chromosomal segments instant access alpha-1 acid glycoprotein-1 conditions privacy policy structural gene heme biosynthetic enzyme aminolevulinate dehydratase somatic hybrids total grains observed inbred mouse strains specific enzyme immunoassay accepting optional cookies usage analysis july 1987 volume 76 chromosomal region 9q34 chromosome 11q23→11qter article log journal finder publish

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         headline:Human δ-aminolevulinate dehydratase: chromosomal localization to 9q34 by in situ hybridization
         description:The structural gene for human δ-aminolevulinate dehydratase (ALA-D) has been localized to chromosomal region 9q34 by in situ hybridization using a [125I]-labeled human δ-aminolevulinate dehydratase cDNA. Of the 150 silver grains analyzed, 25% were localized to chromosome 9q, while 12% and 8% were on chromosomes 1p and 13q, respectively. The single chromosomal region q34 had over 90% of the total grains observed on chromosome 9. In contrast, the grains on chromosomes 1p and 13q were dispersed, consistent with the absence of any human ALD-D pseudogenes. Southern blot analysis of somatic cell hybrids informative for ALA-D (Wang et al. 1985) also was consistent and supported the finding of only one locus for this heme biosynthetic enzyme.
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      headline:Human δ-aminolevulinate dehydratase: chromosomal localization to 9q34 by in situ hybridization
      description:The structural gene for human δ-aminolevulinate dehydratase (ALA-D) has been localized to chromosomal region 9q34 by in situ hybridization using a [125I]-labeled human δ-aminolevulinate dehydratase cDNA. Of the 150 silver grains analyzed, 25% were localized to chromosome 9q, while 12% and 8% were on chromosomes 1p and 13q, respectively. The single chromosomal region q34 had over 90% of the total grains observed on chromosome 9. In contrast, the grains on chromosomes 1p and 13q were dispersed, consistent with the absence of any human ALD-D pseudogenes. Southern blot analysis of somatic cell hybrids informative for ALA-D (Wang et al. 1985) also was consistent and supported the finding of only one locus for this heme biosynthetic enzyme.
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