DOI . ORG {}
Title[redir]:
Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana - ScienceDirect
Description:
We have identified peptides that are relatively resistant to hydrolysis by a recombinant cysteine proteinase, CPB2.8ΔCTE, of Leishmania mexicana, and …
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Keywords {🔍}
peptides, cysteine, cpb, leishmania, mexicana, proteinase, cathepsin, enzyme, peptide, show, cpbδcte, abstract, recombinant, motif, parasite, substrate, trypanosoma, cruzi, amino, library, parasitol, molecular, identified, hydrolysis, inhibition, basichydrophobichydrophobic, proregion, site, cps, genes, cterminal, major, inhibitors, content, biochemical, parasitology, volume, acid, hydrolyzed, extension, specificity, proteinases, cruzain, view, substrates, mol, biochem, access, introduction, references,
Topics {✒️}
motif sequence basic-hydrophobic–hydrophobic basic-hydrophobic-hydrophobic motif basic-hydrophobic–hydrophobic motif section snippets materials danial kahrizi ring-opening n-terminal site reduced amino acids derivatives amino acid stretch c-terminal extension combinatorial peptide library open access content ortho-aminobenzoic acid cysteine protease genes stage-specific proteinases fmoc-glu-eddnp major cysteine proteinase exhibit inhibition constant brazilian research foundations major cysteinyl proteinase wild type parasites wild type levels cysteine proteinase cdna discover specific inhibitors major disease endemic recombinant cysteine proteinase cysteine protease isoforms faa ryl nga antiparasitic drugs directed precise mechanisms involved anti-trypanosomatid agents [22] inco-dc program brazil-dr izaura improve azo dye' electron-deficient acetylenes south korea infection leishmania mexicana mol cysteine proteinase mol proteolytic enzymes expression proteinase inhibition assays human rotavirus circulating complete noncompetitive inhibition binding affinity gene mammalian amastigote form straight line converging cysteine protease inhibitors identify efficient substrates positions p3–p1 p3–p1 sites trypanosoma brucei predicts peptides characteristically contained
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